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Volumn 19, Issue 11, 2014, Pages 19036-19049

Antioxidant mechanism of rutin on hypoxia-induced pulmonary arterial cell proliferation

Author keywords

Hypoxia; NADPH oxidase 4; Proliferation; Reactive oxygen species (ROS); Rutin

Indexed keywords

ANTIOXIDANT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RUTOSIDE;

EID: 84912143891     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules191119036     Document Type: Article
Times cited : (41)

References (33)
  • 2
    • 84859644104 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species in pulmonary hypertension
    • Tabima, D.M.; Frizzell, S.; Gladwin, M.T. Reactive oxygen and nitrogen species in pulmonary hypertension. Free Radic. Biol. Med. 2012, 52, 1970-1986
    • (2012) Free Radic. Biol. Med. , vol.52 , pp. 1970-1986
    • Tabima, D.M.1    Frizzell, S.2    Gladwin, M.T.3
  • 3
    • 0033795729 scopus 로고    scopus 로고
    • Hypoxia-induced pulmonary vascular remodeling: A model for what human disease?
    • Voelkel, N.F.; Tuder, R.M. Hypoxia-induced pulmonary vascular remodeling: A model for what human disease? J. Clin. Invest. 2000, 106, 733-738
    • (2000) J. Clin. Invest. , vol.106 , pp. 733-738
    • Voelkel, N.F.1    Tuder, R.M.2
  • 4
    • 71949129187 scopus 로고    scopus 로고
    • Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
    • Stenmark, K.R.; Meyrick, B.; Galie, N.; Mooi, W.J.; McMurtry, I.F. Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure. Am. J. Physiol. Lung Cell. Mol. Physiol. 2009, 297, L1013-L1032
    • (2009) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.297 , pp. L1013-L1032
    • Stenmark, K.R.1    Meyrick, B.2    Galie, N.3    Mooi, W.J.4    McMurtry, I.F.5
  • 5
    • 4143118866 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pulmonary vascular remodeling: Role in the development of pulmonary hypertension
    • Mandegar, M.; Fung, Y.C.; Huang, W.; Remillard, C.V.; Rubin, L.J.; Yuan, J.X. Cellular and molecular mechanisms of pulmonary vascular remodeling: Role in the development of pulmonary hypertension. Microvasc. Res. 2004, 68, 75-103
    • (2004) Microvasc. Res. , vol.68 , pp. 75-103
    • Mandegar, M.1    Fung, Y.C.2    Huang, W.3    Remillard, C.V.4    Rubin, L.J.5    Yuan, J.X.6
  • 8
    • 84887950782 scopus 로고    scopus 로고
    • The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension
    • Fan, Y.F.; Zhang, R.; Jiang, X.; Wen, L.; Wu, D.C.; Liu, D.; Yuan, P.; Wang, Y.L.; Jing, Z.C. The phosphodiesterase-5 inhibitor vardenafil reduces oxidative stress while reversing pulmonary arterial hypertension. Cardiovasc. Res. 2013, 99, 395-403
    • (2013) Cardiovasc. Res. , vol.99 , pp. 395-403
    • Fan, Y.F.1    Zhang, R.2    Jiang, X.3    Wen, L.4    Wu, D.C.5    Liu, D.6    Yuan, P.7    Wang, Y.L.8    Jing, Z.C.9
  • 9
    • 34147118950 scopus 로고    scopus 로고
    • Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension
    • Konduri, G.G.; Bakhutashvili, I.; Eis, A.; Pritchard, K., Jr. Oxidant stress from uncoupled nitric oxide synthase impairs vasodilation in fetal lambs with persistent pulmonary hypertension. Am. J. Physiol. Heart Circ. Physiol. 2007, 292, H1812-H1820
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.292 , pp. H1812-H1820
    • Konduri, G.G.1    Bakhutashvili, I.2    Eis, A.3    Pritchard, K.4
  • 10
    • 0037131391 scopus 로고    scopus 로고
    • Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes
    • Waypa, G.B.; Marks, J.D.; Mack, M.M.; Boriboun, C.; Mungai, P.T.; Schumacker, P.T. Mitochondrial reactive oxygen species trigger calcium increases during hypoxia in pulmonary arterial myocytes. Circ. Res. 2002, 91, 719-726
    • (2002) Circ. Res. , vol.91 , pp. 719-726
    • Waypa, G.B.1    Marks, J.D.2    Mack, M.M.3    Boriboun, C.4    Mungai, P.T.5    Schumacker, P.T.6
  • 11
    • 0035195281 scopus 로고    scopus 로고
    • ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species
    • Wedgwood, S.; Dettman, R.W.; Black, S.M. ET-1 stimulates pulmonary arterial smooth muscle cell proliferation via induction of reactive oxygen species. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001, 281, L1058-L1067
    • (2001) Am. J. Physiol. Lung Cell. Mol. Physiol. , vol.281 , pp. L1058-L1067
    • Wedgwood, S.1    Dettman, R.W.2    Black, S.M.3
  • 12
    • 84857116578 scopus 로고    scopus 로고
    • Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
    • Ray, P.D.; Huang, B.W.; Tsuji, Y. Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell. Signal. 2012, 24, 981-990
    • (2012) Cell. Signal. , vol.24 , pp. 981-990
    • Ray, P.D.1    Huang, B.W.2    Tsuji, Y.3
  • 13
    • 79251589339 scopus 로고    scopus 로고
    • Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-A-induced apoptosis
    • Basuroy, S.; Tcheranova, D.; Bhattacharya, S.; Leffler, C.W.; Parfenova, H. Nox4 NADPH oxidase-derived reactive oxygen species, via endogenous carbon monoxide, promote survival of brain endothelial cells during TNF-a-induced apoptosis. Am. J. Physiol. Cell Physiol. 2011, 300, C256-C265
    • (2011) Am. J. Physiol. Cell Physiol. , vol.300 , pp. C256-C265
    • Basuroy, S.1    Tcheranova, D.2    Bhattacharya, S.3    Leffler, C.W.4    Parfenova, H.5
  • 15
    • 84875708891 scopus 로고    scopus 로고
    • Vascular remodeling in pulmonary hypertension
    • Shimoda, L.A.; Laurie, S.S. Vascular remodeling in pulmonary hypertension. J. Mol. Med. 2013, 91, 297-309
    • (2013) J. Mol. Med. , vol.91 , pp. 297-309
    • Shimoda, L.A.1    Laurie, S.S.2
  • 16
    • 0031045565 scopus 로고    scopus 로고
    • PCNA: Structure, functions and interactions
    • Kelman, Z. PCNA: Structure, functions and interactions. Oncogene 1997, 14, 629-640
    • (1997) Oncogene , vol.14 , pp. 629-640
    • Kelman, Z.1
  • 17
    • 79956150420 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen (PCNA): A key factor in DNA replication and cell cycle regulation
    • Strzalka, W.; Ziemienowicz, A. Proliferating cell nuclear antigen (PCNA): A key factor in DNA replication and cell cycle regulation. Ann. Bot. 2011, 107, 1127-1140
    • (2011) Ann. Bot. , vol.107 , pp. 1127-1140
    • Strzalka, W.1    Ziemienowicz, A.2
  • 18
    • 84868089977 scopus 로고    scopus 로고
    • Effect of Mitofusin 2 on smooth muscle cells proliferation in hypoxic pulmonary hypertension
    • Zhang, D.; Ma, C.; Li, S.; Ran, Y.; Chen, J.; Lu, P.; Shi, S.; Zhu, D. Effect of Mitofusin 2 on smooth muscle cells proliferation in hypoxic pulmonary hypertension. Microvasc. Res. 2012, 84, 286-296
    • (2012) Microvasc. Res. , vol.84 , pp. 286-296
    • Zhang, D.1    Ma, C.2    Li, S.3    Ran, Y.4    Chen, J.5    Lu, P.6    Shi, S.7    Zhu, D.8
  • 19
    • 84856739946 scopus 로고    scopus 로고
    • Hypoxia-inducible factors in physiology and medicine
    • Semenza, G.L. Hypoxia-inducible factors in physiology and medicine. Cell 2012, 148, 399-408
    • (2012) Cell , vol.148 , pp. 399-408
    • Semenza, G.L.1
  • 20
    • 78751690547 scopus 로고    scopus 로고
    • And the lung: Role of hypoxia-inducible factors in pulmonary development and disease
    • Shimoda, L.A.; Semenza, G.L. HIF and the lung: Role of hypoxia-inducible factors in pulmonary development and disease. Am. J. Respir. Crit. Care Med. 2011, 183, 152-156
    • (2011) Am. J. Respir. Crit. Care Med. , vol.183 , pp. 152-156
    • Shimoda, L.A.1    Hif, L.S.G.2
  • 21
    • 0033947733 scopus 로고    scopus 로고
    • Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions
    • La Casa, C.; Villegas, I.; Alarcón de la Lastra, C.; Motilva, V.; Martin Calero, M.J. Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions. J. Ethnopharmacol. 2000, 71, 45-53
    • (2000) J. Ethnopharmacol. , vol.71 , pp. 45-53
    • La Casa, C.1    Villegas, I.2    Alarcón De La Lastra, C.3    Motilva, V.4    Calero, M.J.5
  • 22
    • 33645103657 scopus 로고    scopus 로고
    • Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats
    • Kamalakkannan, N.; Prince, P.S. Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats. Basic Clin. Pharmacol. Toxicol. 2006, 98, 97-103
    • (2006) Basic Clin. Pharmacol. Toxicol. , vol.98 , pp. 97-103
    • Kamalakkannan, N.1    Prince, P.S.2
  • 23
    • 84875328317 scopus 로고    scopus 로고
    • Mechanisms that underlie the induction of vasodilation in pulmonary artery by rutin
    • Li, Q.; Niu, S.; Wang, R.; Li, Y.; Zhang, R.; Zhu, D. Mechanisms that underlie the induction of vasodilation in pulmonary artery by rutin. Int. Angiol. 2012, 31, 557-564
    • (2012) Int. Angiol. , vol.31 , pp. 557-564
    • Li, Q.1    Niu, S.2    Wang, R.3    Li, Y.4    Zhang, R.5    Zhu, D.6
  • 24
    • 84893484290 scopus 로고    scopus 로고
    • PPARdelta activation inhibits homocysteine-induced p22(phox) expression in EA.hy926 cells through reactive oxygen species/p38MAPK pathway
    • Xiao, G.F.; Xu, S.H.; Chao, Y.; Xie, L.D.; Xu, C.S.; Wang, H.J. PPARdelta activation inhibits homocysteine-induced p22(phox) expression in EA.hy926 cells through reactive oxygen species/p38MAPK pathway. Eur. J. Pharmacol. 2014, 727, 29-34
    • (2014) Eur. J. Pharmacol. , vol.727 , pp. 29-34
    • Xiao, G.F.1    Xu, S.H.2    Chao, Y.3    Xie, L.D.4    Xu, C.S.5    Wang, H.J.6
  • 25
    • 84875109316 scopus 로고    scopus 로고
    • Increased p22(phox)/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn
    • Wedgwood, S.; Lakshminrusimha, S.; Czech, L.; Schumacker, P.T.; Steinhorn, R.H. Increased p22(phox)/Nox4 expression is involved in remodeling through hydrogen peroxide signaling in experimental persistent pulmonary hypertension of the newborn. Antioxid. Redox Signal. 2013, 18, 1765-1776
    • (2013) Antioxid. Redox Signal. , vol.18 , pp. 1765-1776
    • Wedgwood, S.1    Lakshminrusimha, S.2    Czech, L.3    Schumacker, P.T.4    Steinhorn, R.H.5
  • 26
    • 84873110739 scopus 로고    scopus 로고
    • Microtubule proliferation in right ventricular myocytes of rats with monocrotaline-induced pulmonary hypertension
    • Stones, R.; Benoist, D.; Peckham, M.; White, E. Microtubule proliferation in right ventricular myocytes of rats with monocrotaline-induced pulmonary hypertension. J. Mol. Cell. Cardiol. 2013, 56, 91-96
    • (2013) J. Mol. Cell. Cardiol. , vol.56 , pp. 91-96
    • Stones, R.1    Benoist, D.2    Peckham, M.3    White, E.4
  • 27
    • 84861586351 scopus 로고    scopus 로고
    • Novel role for the regulation of mitochondrial fission by hypoxia inducible factor-1a in the control of smooth muscle remodeling and progression of pulmonary hypertension
    • Wolin, M.S. Novel role for the regulation of mitochondrial fission by hypoxia inducible factor-1a in the control of smooth muscle remodeling and progression of pulmonary hypertension. Circ. Res. 2012, 110, 1395-1397
    • (2012) Circ. Res. , vol.110 , pp. 1395-1397
    • Wolin, M.S.1
  • 29
    • 84868251099 scopus 로고    scopus 로고
    • Protective effects of rutin against potassium bromate induced nephrotoxicity in rats
    • Khan, R.A.; Khan, M.R.; Sahreen, S. Protective effects of rutin against potassium bromate induced nephrotoxicity in rats. BMC Complement. Altern. Med. 2012, 12, doi:10.1186/1472-6882-12-204
    • (2012) BMC Complement. Altern. Med. , pp. 12
    • Khan, R.A.1    Khan, M.R.2    Sahreen, S.3
  • 31
    • 79958211266 scopus 로고    scopus 로고
    • Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats
    • Panchal, S.K.; Poudyal, H.; Arumugam, T.V.; Brown, L. Rutin attenuates metabolic changes, nonalcoholic steatohepatitis, and cardiovascular remodeling in high-carbohydrate, high-fat diet-fed rats. J. Nutr. 2011, 141, 1062-1069
    • (2011) J. Nutr. , vol.141 , pp. 1062-1069
    • Panchal, S.K.1    Poudyal, H.2    Arumugam, T.V.3    Brown, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.