메뉴 건너뛰기




Volumn 110, Issue 11, 2012, Pages 1395-1397

Novel role for the regulation of mitochondrial fission by hypoxia inducible factor-1α in the control of smooth muscle remodeling and progression of pulmonary hypertension

Author keywords

differentiation; disease; energy metabolism; pulmonary circulation; smooth muscle proliferation

Indexed keywords

CALCIUM; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; DYNAMIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; POTASSIUM CHANNEL KV1.5; PROTEIN DRP1; PROTEIN MDIVI 1; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

EID: 84861586351     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.270801     Document Type: Review
Times cited : (13)

References (11)
  • 1
    • 84861640093 scopus 로고    scopus 로고
    • Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension
    • Marsboom G, Toth PT, Ryan JJ, et al. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res. 2012;110:1484-1497.
    • (2012) Circ Res , vol.110 , pp. 1484-1497
    • Marsboom, G.1    Toth, P.T.2    Ryan, J.J.3
  • 2
    • 34249689057 scopus 로고    scopus 로고
    • Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
    • Taguchi N, Ishihara N, Jofuku A, Oka T, Mihara K. Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J Biol Chem. 2007;282:11521-11529.
    • (2007) J Biol Chem , vol.282 , pp. 11521-11529
    • Taguchi, N.1    Ishihara, N.2    Jofuku, A.3    Oka, T.4    Mihara, K.5
  • 3
    • 33745155785 scopus 로고    scopus 로고
    • An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: Similarities to human pulmonary arterial hypertension
    • Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thebaud B, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: Similarities to human pulmonary arterial hypertension. Circulation. 2006;113:2630-2641.
    • (2006) Circulation , vol.113 , pp. 2630-2641
    • Bonnet, S.1    Michelakis, E.D.2    Porter, C.J.3    Andrade-Navarro, M.A.4    Thebaud, B.5    Haromy, A.6    Harry, G.7    Moudgil, R.8    McMurtry, M.S.9    Weir, E.K.10    Archer, S.L.11
  • 4
    • 6344257102 scopus 로고    scopus 로고
    • Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
    • McMurtry MS, Bonnet S, Wu X, Dyck JR, Haromy A, Hashimoto K, Michelakis ED. Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res. 2004;95:830-840.
    • (2004) Circ Res , vol.95 , pp. 830-840
    • McMurtry, M.S.1    Bonnet, S.2    Wu, X.3    Dyck, J.R.4    Haromy, A.5    Hashimoto, K.6    Michelakis, E.D.7
  • 5
    • 78649413837 scopus 로고    scopus 로고
    • Mitochondrial fusion and fission in cell life and death
    • Westermann B. Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol. 2010;11:872-884.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 872-884
    • Westermann, B.1
  • 6
    • 36348989007 scopus 로고    scopus 로고
    • Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway
    • Guo X, Chen KH, Guo Y, Liao H, Tang J, Xiao RP. Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway. Circ Res. 2007;101:1113-1122.
    • (2007) Circ Res , vol.101 , pp. 1113-1122
    • Guo, X.1    Chen, K.H.2    Guo, Y.3    Liao, H.4    Tang, J.5    Xiao, R.P.6
  • 7
    • 84255192658 scopus 로고    scopus 로고
    • Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death
    • Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF Jr, Stanley WC, Walsh K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol. 2012;302:H167-H179.
    • (2012) Am J Physiol Heart Circ Physiol , vol.302
    • Papanicolaou, K.N.1    Ngoh, G.A.2    Dabkowski, E.R.3    O'Connell, K.A.4    Stanley, W.C.5    Walsh, K.6
  • 9
    • 84856109625 scopus 로고    scopus 로고
    • Mitochondrial fusion is essential for organelle function and cardiac homeostasis
    • Chen Y, Liu Y, Dorn GW II. Mitochondrial fusion is essential for organelle function and cardiac homeostasis. Circ Res. 2011;109: 1327-1331.
    • (2011) Circ Res , vol.109 , pp. 1327-1331
    • Chen, Y.1    Liu, Y.2    Dorn, G.W.I.I.3
  • 10
    • 84856739946 scopus 로고    scopus 로고
    • Hypoxia-inducible factors in physiology and medicine
    • Semenza GL. Hypoxia-inducible factors in physiology and medicine. Cell. 2012;148:399-408.
    • (2012) Cell , vol.148 , pp. 399-408
    • Semenza, G.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.