3, 3′-diindolylmethane alleviates steatosis and the progression of NASH partly through shifting the imbalance of Treg/Th17 cells to Treg dominance

International Immunopharmacology

Volumn 23, Issue 2, 2014, Pages 489-498

  Liu, Yun ^a   She, Weimin ^a   Wang, Fuping ^a   Li, Jing ^b   Wang, Jiyao ^a   Jiang, Wei ^a  

^a FUDAN UNIVERSITY   (China)

^b TONGJI HOSPITAL OF TONGJI UNIVERSITY   (China)

Author keywords

3,3' diindolylmethane; Aryl hydrocarbon receptor; Nonalcoholic steatohepatitis; Regulatory T cells; Th17 cells; Toll like receptor 4

Indexed keywords

3,3' DIINDOLYLMETHANE; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; NEUTRALIZING ANTIBODY; TOLL LIKE RECEPTOR 4; 3,3'-DIINDOLYLMETHANE; CHOLINE; INDOLE DERIVATIVE; METHIONINE; TLR4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; FATTY LIVER; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; REGULATORY T LYMPHOCYTE; TH17 CELL; UPREGULATION; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DEFICIENCY; DIET; DRUG EFFECTS; GENETICS; LIVER; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; PHYSIOLOGY; SPLEEN;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHOLINE; DIET; FEMALE; INDOLES; LIVER; METHIONINE; MICE; MICE, INBRED C57BL; NON-ALCOHOLIC FATTY LIVER DISEASE; SPLEEN; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; TOLL-LIKE RECEPTOR 4;

EID: 84912107546     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.09.024     Document Type: Article

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