메뉴 건너뛰기




Volumn 17, Issue 6, 2010, Pages 1025-1033

Nitric oxide repression of Nanog promotes mouse embryonic stem cell differentiation

Author keywords

Differentiation; Embryonic stem cell; Nanog; Nitric oxide; Oct4 repression; Self renewal

Indexed keywords

DIETHYLENETRIAMINE; HEPATOCYTE NUCLEAR FACTOR 1BETA; HEPATOCYTE NUCLEAR FACTOR 3BETA; HISTONE H3; LYSINE; NITRIC OXIDE; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN P53; REPRESSOR PROTEIN; SERINE; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX17; VALPROIC ACID;

EID: 77952238024     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.204     Document Type: Article
Times cited : (59)

References (40)
  • 1
    • 0034028901 scopus 로고    scopus 로고
    • Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells
    • DOI 10.1038/74199
    • Niwa H, Miyazaki J, Smith AG. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet 2000; 24: 372-376. (Pubitemid 30187435)
    • (2000) Nature Genetics , vol.24 , Issue.4 , pp. 372-376
    • Niwa, H.1    Miyazaki, J.-I.2    Smith, A.G.3
  • 2
    • 0037806031 scopus 로고    scopus 로고
    • The homeoprotein nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
    • DOI 10.1016/S0092-8674(03)00393-3
    • Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K et al. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003; 113: 631-642. (Pubitemid 36694188)
    • (2003) Cell , vol.113 , Issue.5 , pp. 631-642
    • Mitsui, K.1    Tokuzawa, Y.2    Itoh, H.3    Segawa, K.4    Murakami, M.5    Takahashi, K.6    Maruyama, M.7    Maeda, M.8    Yamanaka, S.9
  • 3
    • 0038143611 scopus 로고    scopus 로고
    • Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
    • DOI 10.1016/S0092-8674(03)00392-1
    • Chambers I, Colby D, Robertson M, Nichols J, Lee S, Tweedie S et al. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003; 113: 643-655. (Pubitemid 36694189)
    • (2003) Cell , vol.113 , Issue.5 , pp. 643-655
    • Chambers, I.1    Colby, D.2    Robertson, M.3    Nichols, J.4    Lee, S.5    Tweedie, S.6    Smith, A.7
  • 5
    • 33846184752 scopus 로고    scopus 로고
    • Nanog and transcriptional networks in embryonic stem cell pluripotency
    • DOI 10.1038/sj.cr.7310125, PII 7310125
    • Pan G, Thomson JA. Nanog and transcriptional networks in embryonic stem cell pluripotency. Cell Res 2007; 17: 42-49. (Pubitemid 46096423)
    • (2007) Cell Research , vol.17 , Issue.1 , pp. 42-49
    • Pan, G.1    Thomson, J.A.2
  • 6
    • 10944241060 scopus 로고    scopus 로고
    • Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation
    • DOI 10.1242/jcs.01489
    • Hamazaki T, Oka M, Yamanaka S, Terada N. Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation. J Cell Sci 2004; 117 (Part 23): 5681-5686. (Pubitemid 40012213)
    • (2004) Journal of Cell Science , vol.117 , Issue.23 , pp. 5681-5686
    • Hamazaki, T.1    Oka, M.2    Yamanaka, S.3    Terada, N.4
  • 7
    • 13944273471 scopus 로고    scopus 로고
    • P53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression
    • DOI 10.1038/ncb1211
    • Lin T, Chao C, Saito S, Mazur SJ, Murphy ME, Appella E et al. p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression. Nat Cell Biol 2005; 7: 165-171. (Pubitemid 40268131)
    • (2005) Nature Cell Biology , vol.7 , Issue.2 , pp. 165-171
    • Lin, T.1    Chao, C.2    Saito, S.3    Mazur, S.J.4    Murphy, M.E.5    Appella, E.6    Xu, Y.7
  • 8
    • 39749087530 scopus 로고    scopus 로고
    • SIRT1 regulates apoptosis and nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
    • DOI 10.1016/j.stem.2008.01.002, PII S1934590908000039
    • Han MK, Song EK, Guo Y, Ou X, Mantel C, Broxmeyer HE. SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2008; 2: 241-251. (Pubitemid 351298591)
    • (2008) Cell Stem Cell , vol.2 , Issue.3 , pp. 241-251
    • Han, M.-K.1    Song, E.-K.2    Guo, Y.3    Ou, X.4    Mantel, C.5    Broxmeyer, H.E.6
  • 9
    • 0030797585 scopus 로고    scopus 로고
    • Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
    • DOI 10.1016/S0092-8674(00)80521-8
    • Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997; 90: 595-606. (Pubitemid 27357952)
    • (1997) Cell , vol.90 , Issue.4 , pp. 595-606
    • Gu, W.1    Roeder, R.G.2
  • 10
    • 1042302747 scopus 로고    scopus 로고
    • Histone deacetylase activity is required for embryonic stem cell differentiation
    • DOI 10.1002/gene.10250
    • Lee JH, Hart SR, Skalnik DG. Histone deacetylase activity is required for embryonic stem cell differentiation. Genesis 2004; 38: 32-38. (Pubitemid 38197607)
    • (2004) Genesis , vol.38 , Issue.1 , pp. 32-38
    • Lee, J.-H.1    Hart, S.R.L.2    Skalnik, D.G.3
  • 11
    • 35348982301 scopus 로고    scopus 로고
    • Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
    • DOI 10.1101/gad.1588207
    • Loh YH, Zhang W, Chen X, George J, Ng HH. Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev 2007; 21: 2545-2557. (Pubitemid 47607666)
    • (2007) Genes and Development , vol.21 , Issue.20 , pp. 2545-2557
    • Loh, Y.-H.1    Zhang, W.2    Chen, X.3    George, J.4    Ng, H.-H.5
  • 18
    • 34249726101 scopus 로고    scopus 로고
    • Arginine vasopressin-mediated cardiac differentiation: Insights into the role of its receptors and nitric oxide signaling
    • DOI 10.1074/jbc.M610769200
    • Gassanov N, Jankowski M, Danalache B, Wang D, Grygorczyk R, Hoppe UC et al. Arginine vasopressin-mediated cardiac differentiation: insights into the role of its receptors and nitric oxide signaling. J Biol Chem 2007; 282: 11255-11265. (Pubitemid 47100804)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.15 , pp. 11255-11265
    • Gassanov, N.1    Jankowski, M.2    Danalache, B.3    Wang, D.4    Grygorczyk, R.5    Hoppe, U.C.6    Gutkowska, J.7
  • 20
    • 57749107735 scopus 로고    scopus 로고
    • Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells
    • Mujoo K, Sharin VG, Bryan NS, Krumenacker JS, Sloan C, Parveen S et al. Role of nitric oxide signaling components in differentiation of embryonic stem cells into myocardial cells. Proc Natl Acad Sci USA 2008; 105: 18924-18929.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18924-18929
    • Mujoo, K.1    Sharin, V.G.2    Bryan, N.S.3    Krumenacker, J.S.4    Sloan, C.5    Parveen, S.6
  • 21
    • 0037013199 scopus 로고    scopus 로고
    • P53 activation by nitric oxide involves down-regulation of Mdm2
    • DOI 10.1074/jbc.M112068200
    • Wang X, Michael D, de Murcia G, Oren M. p53 Activation by nitric oxide involves down-regulation of Mdm2. J Biol Chem 2002; 277: 15697-15702. (Pubitemid 34967843)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.18 , pp. 15697-15702
    • Wang, X.1    Michael, D.2    De Murcia, G.3    Oren, M.4
  • 22
    • 2542477269 scopus 로고    scopus 로고
    • Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53-and Bax-dependent pathways
    • Yung HW, Bal-Price AK, Brown GC, Tolkovsky AM. Nitric oxide-induced cell death of cerebrocortical murine astrocytes is mediated through p53-and Bax-dependent pathways. J Neurochem 2004; 89: 812-821.
    • (2004) J Neurochem , vol.89 , pp. 812-821
    • Yung, H.W.1    Bal-Price, A.K.2    Brown, G.C.3    Tolkovsky, A.M.4
  • 23
    • 22244454400 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in lymphoblastoid and fibroblast cells dependent on the phosphorylation and activation of p53
    • DOI 10.1158/0008-5472.CAN-04-4254
    • McLaughlin LM, Demple B. Nitric oxide-induced apoptosis in lymphoblastoid and fibroblast cells dependent on the phosphorylation and activation of p53. Cancer Res 2005; 65: 6097-6104. (Pubitemid 40994394)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 6097-6104
    • McLaughlin, L.M.1    Demple, B.2
  • 25
    • 33749633094 scopus 로고    scopus 로고
    • The Grb2/Mek pathway represses nanog in murine embryonic stem cells
    • DOI 10.1128/MCB.00508-06
    • Hamazaki T, Kehoe SM, Nakano T, Terada N. The Grb2/Mek pathway represses Nanog in murine embryonic stem cells. Mol Cell Biol 2006; 26: 7539-7549. (Pubitemid 44547704)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.20 , pp. 7539-7549
    • Hamazaki, T.1    Kehoe, S.M.2    Nakano, T.3    Terada, N.4
  • 26
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, Chen X et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 2006; 38: 431-440.
    • (2006) Nat Genet , vol.38 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3    Vega, V.B.4    Zhang, W.5    Chen, X.6
  • 28
    • 51649129472 scopus 로고    scopus 로고
    • Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells
    • Maimets T, Neganova I, Armstrong L, Lako M. Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells. Oncogene 2008; 27: 5277-5287.
    • (2008) Oncogene , vol.27 , pp. 5277-5287
    • Maimets, T.1    Neganova, I.2    Armstrong, L.3    Lako, M.4
  • 29
    • 41849151748 scopus 로고    scopus 로고
    • Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
    • Kroon E, Martinson LA, Kadoya K, Bang AG, Kelly OG, Eliazer S et al. Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol 2008; 26: 443-452.
    • (2008) Nat Biotechnol , vol.26 , pp. 443-452
    • Kroon, E.1    Martinson, L.A.2    Kadoya, K.3    Bang, A.G.4    Kelly, O.G.5    Eliazer, S.6
  • 31
    • 33750846133 scopus 로고    scopus 로고
    • Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
    • D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG et al. Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 2006; 24: 1392-1401.
    • (2006) Nat Biotechnol , vol.24 , pp. 1392-1401
    • D'Amour, K.A.1    Bang, A.G.2    Eliazer, S.3    Kelly, O.G.4    Agulnick, A.D.5    Smart, N.G.6
  • 32
    • 33646757232 scopus 로고    scopus 로고
    • The complexity of p53 stabilization and activation
    • Lavin MF, Gueven N. The complexity of p53 stabilization and activation. Cell Death Differ 2006; 13: 941-950.
    • (2006) Cell Death Differ , vol.13 , pp. 941-950
    • Lavin, M.F.1    Gueven, N.2
  • 33
    • 0035895904 scopus 로고    scopus 로고
    • Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription
    • Blaydes JP, Luciani MG, Pospisilova S, Ball HM, Vojtesek B, Hupp TR. Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription. J Biol Chem 2001; 276: 4699-4708.
    • (2001) J Biol Chem , vol.276 , pp. 4699-4708
    • Blaydes, J.P.1    Luciani, M.G.2    Pospisilova, S.3    Ball, H.M.4    Vojtesek, B.5    Hupp, T.R.6
  • 34
    • 13544256594 scopus 로고    scopus 로고
    • The post-translational phosphorylation and acetylation modification profile is not the determining factor in targeting endogenous stress-induced p53 to mitochondria
    • Nemajerova A, Erster S, Moll UM. The post-translational phosphorylation and acetylation modification profile is not the determining factor in targeting endogenous stress-induced p53 to mitochondria. Cell Death Differ 2005; 12: 197-200.
    • (2005) Cell Death Differ , vol.12 , pp. 197-200
    • Nemajerova, A.1    Erster, S.2    Moll, U.M.3
  • 35
    • 0035380103 scopus 로고    scopus 로고
    • Mechanisms of transcriptional memory
    • Francis NJ, Kingston RE. Mechanisms of transcriptional memory. Nat Rev 2001; 2: 409-421.
    • (2001) Nat Rev , vol.2 , pp. 409-421
    • Francis, N.J.1    Kingston, R.E.2
  • 36
    • 53549088061 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors
    • Haumaitre C, Lenoir O, Scharfmann R. Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors. Mol Cell Biol 2008; 28: 6373-6383.
    • (2008) Mol Cell Biol , vol.28 , pp. 6373-6383
    • Haumaitre, C.1    Lenoir, O.2    Scharfmann, R.3
  • 37
    • 39549120668 scopus 로고    scopus 로고
    • Nicotinamide induces differentiation of embryonic stem cells into insulin-secreting cells
    • Vaca P, Berna G, Araujo R, Carneiro EM, Bedoya FJ, Soria B et al. Nicotinamide induces differentiation of embryonic stem cells into insulin-secreting cells. Exp Cell Res 2008; 314: 969-974.
    • (2008) Exp Cell Res , vol.314 , pp. 969-974
    • Vaca, P.1    Berna, G.2    Araujo, R.3    Carneiro, E.M.4    Bedoya, F.J.5    Soria, B.6
  • 39
    • 10744225452 scopus 로고    scopus 로고
    • A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells
    • (Oxford, England)
    • Hovatta O, Mikkola M, Gertow K, Stromberg AM, Inzunza J, Hreinsson J et al. A culture system using human foreskin fibroblasts as feeder cells allows production of human embryonic stem cells. Hum Reprod (Oxford, England) 2003; 18: 1404-1409.
    • (2003) Hum Reprod , vol.18 , pp. 1404-1409
    • Hovatta, O.1    Mikkola, M.2    Gertow, K.3    Stromberg, A.M.4    Inzunza, J.5    Hreinsson, J.6
  • 40
    • 33750628012 scopus 로고    scopus 로고
    • Isolation and characterization of residual undifferentiated mouse embryonic stem cells from embryoid body cultures by fluorescence tracking
    • Ensenat-Waser R, Santana A, Vicente-Salar N, Cigudosa JC, Roche E, Soria B et al. Isolation and characterization of residual undifferentiated mouse embryonic stem cells from embryoid body cultures by fluorescence tracking. In Vitro Cell Dev Biol Anim 2006; 42: 115-123.
    • (2006) In Vitro Cell Dev Biol Anim , vol.42 , pp. 115-123
    • Ensenat-Waser, R.1    Santana, A.2    Vicente-Salar, N.3    Cigudosa, J.C.4    Roche, E.5    Soria, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.