Simultaneous inhibition of T helper 2 and T regulatory cell differentiation by small molecules enhances bacillus calmette-guerin vaccine efficacy against tuberculosis

Journal of Biological Chemistry

Volumn 289, Issue 48, 2014, Pages 33404-33411

  Bhattacharya, Debapriya ^a   Dwivedi, Ved Prakash ^a   Kumar, Santosh ^a   Reddy, Madhava C ^b   Van Kaer, Luc ^c   Moodley, Prashini ^a   Das, Gobardhan ^a,d  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b YOGI VEMANA UNIVERSITY   (India)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOLOGY; CELLS; CYTOLOGY; IMMUNE SYSTEM; SULFUR COMPOUNDS; VACCINES;

CELL DIFFERENTIATION; CELL MEMORY; CELL RESPONSE; IMMUNE RESPONSE; MYCOBACTERIUM TUBERCULOSIS; PHARMACOLOGICAL INHIBITORS; SMALL MOLECULES; VACCINE EFFICACIES;

T-CELLS;

BCG VACCINE; D 4476; GAMMA INTERFERON; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; SUPLATAST TOSYLATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 4-(4-(2,3-DIHYDROBENZO(1,4)DIOXIN-6-YL)-5-PYRIDIN-2-YL-1H-IMIDAZOL-2-YL)BENZAMIDE; ANTIALLERGIC AGENT; ARYLSULFONIC ACID DERIVATIVE; BENZAMIDE DERIVATIVE; IMIDAZOLE DERIVATIVE; SULFONIUM DERIVATIVE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL LOAD; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG POTENTIATION; IMMUNE RESPONSE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTOPOIESIS; MEMORY CELL; MOUSE; NONHUMAN; PROTECTION; REGULATORY T LYMPHOCYTE; TH2 CELL; TREATMENT DURATION; TUBERCULOSIS; ANIMAL; BAGG ALBINO MOUSE; CELL DIFFERENTIATION; DRUG EFFECTS; IMMUNOLOGY; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; PATHOLOGY; TUBERCULOSIS, PULMONARY;

MYCOBACTERIUM BOVIS BCG;

ANIMALS; ANTI-ALLERGIC AGENTS; ARYLSULFONATES; BENZAMIDES; CELL DIFFERENTIATION; IMIDAZOLES; MICE; MICE, INBRED BALB C; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; SULFONIUM COMPOUNDS; T-LYMPHOCYTES, REGULATORY; TH2 CELLS; TUBERCULOSIS VACCINES; TUBERCULOSIS, PULMONARY;

EID: 84912102852     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.600452     Document Type: Article

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