-
1
-
-
77950953984
-
PlGF blockade does not inhibit angiogenesis during primary tumor growth
-
Bais C., Wu X., Yao J., Yang S., Crawford Y., McCutcheon K., Tan C., Kolumam G., Vernes J.M., Eastham-Anderson J., et al. PlGF blockade does not inhibit angiogenesis during primary tumor growth. Cell 2010, 141:166-177.
-
(2010)
Cell
, vol.141
, pp. 166-177
-
-
Bais, C.1
Wu, X.2
Yao, J.3
Yang, S.4
Crawford, Y.5
McCutcheon, K.6
Tan, C.7
Kolumam, G.8
Vernes, J.M.9
Eastham-Anderson, J.10
-
2
-
-
0037236642
-
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
-
Brancaccio M., Fratta L., Notte A., Hirsch E., Poulet R., Guazzone S., De Acetis M., Vecchione C., Marino G., Altruda F., et al. Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat. Med. 2003, 9:68-75.
-
(2003)
Nat. Med.
, vol.9
, pp. 68-75
-
-
Brancaccio, M.1
Fratta, L.2
Notte, A.3
Hirsch, E.4
Poulet, R.5
Guazzone, S.6
De Acetis, M.7
Vecchione, C.8
Marino, G.9
Altruda, F.10
-
3
-
-
0033822747
-
CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension
-
Bush E., Maeda N., Kuziel W.A., Dawson T.C., Wilcox J.N., DeLeon H., Taylor W.R. CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension. Hypertension 2000, 36:360-363.
-
(2000)
Hypertension
, vol.36
, pp. 360-363
-
-
Bush, E.1
Maeda, N.2
Kuziel, W.A.3
Dawson, T.C.4
Wilcox, J.N.5
DeLeon, H.6
Taylor, W.R.7
-
4
-
-
84869045313
-
Placental growth factor and cardiac inflammation
-
Carnevale D., Lembo G. Placental growth factor and cardiac inflammation. Trends Cardiovasc. Med. 2012, 22:209-212.
-
(2012)
Trends Cardiovasc. Med.
, vol.22
, pp. 209-212
-
-
Carnevale, D.1
Lembo, G.2
-
5
-
-
80052970975
-
Placental growth factor regulates cardiac inflammation through the tissue inhibitor of metalloproteinases-3/tumor necrosis factor-α-converting enzyme axis: crucial role for adaptive cardiac remodeling during cardiac pressure overload
-
Carnevale D., Cifelli G., Mascio G., Madonna M., Sbroggiò M., Perrino C., Persico M.G., Frati G., Lembo G. Placental growth factor regulates cardiac inflammation through the tissue inhibitor of metalloproteinases-3/tumor necrosis factor-α-converting enzyme axis: crucial role for adaptive cardiac remodeling during cardiac pressure overload. Circulation 2011, 124:1337-1350.
-
(2011)
Circulation
, vol.124
, pp. 1337-1350
-
-
Carnevale, D.1
Cifelli, G.2
Mascio, G.3
Madonna, M.4
Sbroggiò, M.5
Perrino, C.6
Persico, M.G.7
Frati, G.8
Lembo, G.9
-
6
-
-
84555177773
-
PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism
-
Carnevale D., Vecchione C., Mascio G., Esposito G., Cifelli G., Martinello K., Landolfi A., Selvetella G., Grieco P., Damato A., et al. PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism. Cardiovasc. Res. 2012, 93:200-209.
-
(2012)
Cardiovasc. Res.
, vol.93
, pp. 200-209
-
-
Carnevale, D.1
Vecchione, C.2
Mascio, G.3
Esposito, G.4
Cifelli, G.5
Martinello, K.6
Landolfi, A.7
Selvetella, G.8
Grieco, P.9
Damato, A.10
-
7
-
-
83655167191
-
Overexpression of tissue inhibitor of metalloproteinase 3 in macrophages reduces atherosclerosis in low-density lipoprotein receptor knockout mice
-
Casagrande V., Menghini R., Menini S., Marino A., Marchetti V., Cavalera M., Fabrizi M., Hribal M.L., Pugliese G., Gentileschi P., et al. Overexpression of tissue inhibitor of metalloproteinase 3 in macrophages reduces atherosclerosis in low-density lipoprotein receptor knockout mice. Arterioscler. Thromb. Vasc. Biol. 2012, 32:74-81.
-
(2012)
Arterioscler. Thromb. Vasc. Biol.
, vol.32
, pp. 74-81
-
-
Casagrande, V.1
Menghini, R.2
Menini, S.3
Marino, A.4
Marchetti, V.5
Cavalera, M.6
Fabrizi, M.7
Hribal, M.L.8
Pugliese, G.9
Gentileschi, P.10
-
8
-
-
69349103215
-
Shattuck Lecture. The hypertension paradox-more uncontrolled disease despite improved therapy
-
Chobanian A.V. Shattuck Lecture. The hypertension paradox-more uncontrolled disease despite improved therapy. N.Engl. J. Med. 2009, 361:878-887.
-
(2009)
N.Engl. J. Med.
, vol.361
, pp. 878-887
-
-
Chobanian, A.V.1
-
9
-
-
81255195551
-
Under pressure: the search for the essential mechanisms of hypertension
-
Coffman T.M. Under pressure: the search for the essential mechanisms of hypertension. Nat. Med. 2011, 17:1402-1409.
-
(2011)
Nat. Med.
, vol.17
, pp. 1402-1409
-
-
Coffman, T.M.1
-
10
-
-
20144388724
-
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system
-
Crowley S.D., Gurley S.B., Oliverio M.I., Pazmino A.K., Griffiths R., Flannery P.J., Spurney R.F., Kim H.S., Smithies O., Le T.H., Coffman T.M. Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. J.Clin. Invest. 2005, 115:1092-1099.
-
(2005)
J.Clin. Invest.
, vol.115
, pp. 1092-1099
-
-
Crowley, S.D.1
Gurley, S.B.2
Oliverio, M.I.3
Pazmino, A.K.4
Griffiths, R.5
Flannery, P.J.6
Spurney, R.F.7
Kim, H.S.8
Smithies, O.9
Le, T.H.10
Coffman, T.M.11
-
12
-
-
84863903383
-
Myocardial infarction accelerates atherosclerosis
-
Dutta P., Courties G., Wei Y., Leuschner F., Gorbatov R., Robbins C.S., Iwamoto Y., Thompson B., Carlson A.L., Heidt T., et al. Myocardial infarction accelerates atherosclerosis. Nature 2012, 487:325-329.
-
(2012)
Nature
, vol.487
, pp. 325-329
-
-
Dutta, P.1
Courties, G.2
Wei, Y.3
Leuschner, F.4
Gorbatov, R.5
Robbins, C.S.6
Iwamoto, Y.7
Thompson, B.8
Carlson, A.L.9
Heidt, T.10
-
13
-
-
33845667407
-
Plgf-/-eNos-/- mice show defective angiogenesis associated with increased oxidative stress in response to tissue ischemia
-
Gigante B., Morlino G., Gentile M.T., Persico M.G., De Falco S. Plgf-/-eNos-/- mice show defective angiogenesis associated with increased oxidative stress in response to tissue ischemia. FASEB J. 2006, 20:970-972.
-
(2006)
FASEB J.
, vol.20
, pp. 970-972
-
-
Gigante, B.1
Morlino, G.2
Gentile, M.T.3
Persico, M.G.4
De Falco, S.5
-
14
-
-
79953743181
-
AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure
-
Gurley S.B., Riquier-Brison A.D., Schnermann J., Sparks M.A., Allen A.M., Haase V.H., Snouwaert J.N., Le T.H., McDonough A.A., Koller B.H., Coffman T.M. AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure. Cell Metab. 2011, 13:469-475.
-
(2011)
Cell Metab.
, vol.13
, pp. 469-475
-
-
Gurley, S.B.1
Riquier-Brison, A.D.2
Schnermann, J.3
Sparks, M.A.4
Allen, A.M.5
Haase, V.H.6
Snouwaert, J.N.7
Le, T.H.8
McDonough, A.A.9
Koller, B.H.10
Coffman, T.M.11
-
15
-
-
34948825774
-
Role of the Tcell in the genesis of angiotensin II induced hypertension and vascular dysfunction
-
Guzik T.J., Hoch N.E., Brown K.A., McCann L.A., Rahman A., Dikalov S., Goronzy J., Weyand C., Harrison D.G. Role of the Tcell in the genesis of angiotensin II induced hypertension and vascular dysfunction. J.Exp. Med. 2007, 204:2449-2460.
-
(2007)
J.Exp. Med.
, vol.204
, pp. 2449-2460
-
-
Guzik, T.J.1
Hoch, N.E.2
Brown, K.A.3
McCann, L.A.4
Rahman, A.5
Dikalov, S.6
Goronzy, J.7
Weyand, C.8
Harrison, D.G.9
-
16
-
-
84872282761
-
The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension
-
Harrison D.G. The mosaic theory revisited: common molecular mechanisms coordinating diverse organ and cellular events in hypertension. J.Am. Soc. Hypertens. 2013, 7:68-74.
-
(2013)
J.Am. Soc. Hypertens.
, vol.7
, pp. 68-74
-
-
Harrison, D.G.1
-
17
-
-
77949775126
-
Role of the adaptive immune system in hypertension
-
Harrison D.G., Vinh A., Lob H., Madhur M.S. Role of the adaptive immune system in hypertension. Curr. Opin. Pharmacol. 2010, 10:203-207.
-
(2010)
Curr. Opin. Pharmacol.
, vol.10
, pp. 203-207
-
-
Harrison, D.G.1
Vinh, A.2
Lob, H.3
Madhur, M.S.4
-
18
-
-
2442710252
-
Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling
-
Ishibashi M., Hiasa K., Zhao Q., Inoue S., Ohtani K., Kitamoto S., Tsuchihashi M., Sugaya T., Charo I.F., Kura S., et al. Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling. Circ. Res. 2004, 94:1203-1210.
-
(2004)
Circ. Res.
, vol.94
, pp. 1203-1210
-
-
Ishibashi, M.1
Hiasa, K.2
Zhao, Q.3
Inoue, S.4
Ohtani, K.5
Kitamoto, S.6
Tsuchihashi, M.7
Sugaya, T.8
Charo, I.F.9
Kura, S.10
-
19
-
-
0034100147
-
Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases
-
Kim S., Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal diseases. Pharmacol. Rev. 2000, 52:11-34.
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 11-34
-
-
Kim, S.1
Iwao, H.2
-
20
-
-
34548152814
-
Splanchnic circulation is a critical neural target in angiotensin II salt hypertension in rats
-
King A.J., Osborn J.W., Fink G.D. Splanchnic circulation is a critical neural target in angiotensin II salt hypertension in rats. Hypertension 2007, 50:547-556.
-
(2007)
Hypertension
, vol.50
, pp. 547-556
-
-
King, A.J.1
Osborn, J.W.2
Fink, G.D.3
-
21
-
-
43049097195
-
Global burden of blood-pressure-related disease, 2001
-
International Society ofHypertension
-
Lawes C.M., Vander Hoorn S., Rodgers A. Global burden of blood-pressure-related disease, 2001. Lancet 2008, 371:1513-1518. International Society ofHypertension.
-
(2008)
Lancet
, vol.371
, pp. 1513-1518
-
-
Lawes, C.M.1
Vander Hoorn, S.2
Rodgers, A.3
-
22
-
-
80053655134
-
Renal proximal tubule angiotensin AT1A receptors regulate blood pressure
-
Li H., Weatherford E.T., Davis D.R., Keen H.L., Grobe J.L., Daugherty A., Cassis L.A., Allen A.M., Sigmund C.D. Renal proximal tubule angiotensin AT1A receptors regulate blood pressure. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2011, 301:R1067-R1077.
-
(2011)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.301
, pp. R1067-R1077
-
-
Li, H.1
Weatherford, E.T.2
Davis, D.R.3
Keen, H.L.4
Grobe, J.L.5
Daugherty, A.6
Cassis, L.A.7
Allen, A.M.8
Sigmund, C.D.9
-
23
-
-
0033539947
-
Inhibition of the putative tumor suppressor gene TIMP-3 by tumor-derived p53 mutants and wild type p53
-
Loging W.T., Reisman D. Inhibition of the putative tumor suppressor gene TIMP-3 by tumor-derived p53 mutants and wild type p53. Oncogene 1999, 18:7608-7615.
-
(1999)
Oncogene
, vol.18
, pp. 7608-7615
-
-
Loging, W.T.1
Reisman, D.2
-
24
-
-
0036344495
-
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
-
Luttun A., Tjwa M., Moons L., Wu Y., Angelillo-Scherrer A., Liao F., Nagy J.A., Hooper A., Priller J., De Klerck B., et al. Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat. Med. 2002, 8:831-840.
-
(2002)
Nat. Med.
, vol.8
, pp. 831-840
-
-
Luttun, A.1
Tjwa, M.2
Moons, L.3
Wu, Y.4
Angelillo-Scherrer, A.5
Liao, F.6
Nagy, J.A.7
Hooper, A.8
Priller, J.9
De Klerck, B.10
-
25
-
-
84867735325
-
Synapses, signals, CDs, and cytokines: interactions of the autonomic nervous system and immunity in hypertension
-
Madhur M.S., Harrison D.G. Synapses, signals, CDs, and cytokines: interactions of the autonomic nervous system and immunity in hypertension. Circ. Res. 2012, 111:1113-1116.
-
(2012)
Circ. Res.
, vol.111
, pp. 1113-1116
-
-
Madhur, M.S.1
Harrison, D.G.2
-
26
-
-
77955171998
-
Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension
-
Marvar P.J., Thabet S.R., Guzik T.J., Lob H.E., McCann L.A., Weyand C., Gordon F.J., Harrison D.G. Central and peripheral mechanisms of T-lymphocyte activation and vascular inflammation produced by angiotensin II-induced hypertension. Circ. Res. 2010, 107:263-270.
-
(2010)
Circ. Res.
, vol.107
, pp. 263-270
-
-
Marvar, P.J.1
Thabet, S.R.2
Guzik, T.J.3
Lob, H.E.4
McCann, L.A.5
Weyand, C.6
Gordon, F.J.7
Harrison, D.G.8
-
27
-
-
70249085585
-
Stromal cell contributions to the homeostasis and functionality of the immune system
-
Mueller S.N., Germain R.N. Stromal cell contributions to the homeostasis and functionality of the immune system. Nat. Rev. Immunol. 2009, 9:618-629.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 618-629
-
-
Mueller, S.N.1
Germain, R.N.2
-
29
-
-
77952634073
-
Angiotensin II upregulates the expression of placental growth factor in human vascular endothelial cells and smooth muscle cells
-
Pan P., Fu H., Zhang L., Huang H., Luo F., Wu W., Guo Y., Liu X. Angiotensin II upregulates the expression of placental growth factor in human vascular endothelial cells and smooth muscle cells. BMC Cell Biol. 2010, 11:36.
-
(2010)
BMC Cell Biol.
, vol.11
, pp. 36
-
-
Pan, P.1
Fu, H.2
Zhang, L.3
Huang, H.4
Luo, F.5
Wu, W.6
Guo, Y.7
Liu, X.8
-
30
-
-
0043156082
-
Placenta growth factor activates monocytes and correlates with sickle cell disease severity
-
Perelman N., Selvaraj S.K., Batra S., Luck L.R., Erdreich-Epstein A., Coates T.D., Kalra V.K., Malik P. Placenta growth factor activates monocytes and correlates with sickle cell disease severity. Blood 2003, 102:1506-1514.
-
(2003)
Blood
, vol.102
, pp. 1506-1514
-
-
Perelman, N.1
Selvaraj, S.K.2
Batra, S.3
Luck, L.R.4
Erdreich-Epstein, A.5
Coates, T.D.6
Kalra, V.K.7
Malik, P.8
-
31
-
-
0037423858
-
VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism
-
Pipp F., Heil M., Issbrücker K., Ziegelhoeffer T., Martin S., van den Heuvel J., Weich H., Fernandez B., Golomb G., Carmeliet P., et al. VEGFR-1-selective VEGF homologue PlGF is arteriogenic: evidence for a monocyte-mediated mechanism. Circ. Res. 2003, 92:378-385.
-
(2003)
Circ. Res.
, vol.92
, pp. 378-385
-
-
Pipp, F.1
Heil, M.2
Issbrücker, K.3
Ziegelhoeffer, T.4
Martin, S.5
van den Heuvel, J.6
Weich, H.7
Fernandez, B.8
Golomb, G.9
Carmeliet, P.10
-
32
-
-
84861204062
-
Regulation of Th1/Th2 polarization by tissue inhibitor of metalloproteinase-3 via modulating dendritic cells
-
Shao Q., Ning H., Lv J., Liu Y., Zhao X., Ren G., Feng A., Xie Q., Sun J., Song B., et al. Regulation of Th1/Th2 polarization by tissue inhibitor of metalloproteinase-3 via modulating dendritic cells. Blood 2012, 119:4636-4644.
-
(2012)
Blood
, vol.119
, pp. 4636-4644
-
-
Shao, Q.1
Ning, H.2
Lv, J.3
Liu, Y.4
Zhao, X.5
Ren, G.6
Feng, A.7
Xie, Q.8
Sun, J.9
Song, B.10
-
33
-
-
55249097716
-
Intracellular signals of Tcell costimulation
-
Song J., Lei F.T., Xiong X., Haque R. Intracellular signals of Tcell costimulation. Cell. Mol. Immunol. 2008, 5:239-247.
-
(2008)
Cell. Mol. Immunol.
, vol.5
, pp. 239-247
-
-
Song, J.1
Lei, F.T.2
Xiong, X.3
Haque, R.4
-
35
-
-
0017194521
-
Evidence for an initial, thymus independent and a chronic, thymus dependent phase of DOCA and salt hypertension in mice
-
Svendsen U.G. Evidence for an initial, thymus independent and a chronic, thymus dependent phase of DOCA and salt hypertension in mice. Acta Pathol. Microbiol. Scand. [A] 1976, 84:523-528.
-
(1976)
Acta Pathol. Microbiol. Scand. [A]
, vol.84
, pp. 523-528
-
-
Svendsen, U.G.1
-
36
-
-
68149119072
-
Identification of splenic reservoir monocytes and their deployment to inflammatory sites
-
Swirski F.K., Nahrendorf M., Etzrodt M., Wildgruber M., Cortez-Retamozo V., Panizzi P., Figueiredo J.L., Kohler R.H., Chudnovskiy A., Waterman P., et al. Identification of splenic reservoir monocytes and their deployment to inflammatory sites. Science 2009, 325:612-616.
-
(2009)
Science
, vol.325
, pp. 612-616
-
-
Swirski, F.K.1
Nahrendorf, M.2
Etzrodt, M.3
Wildgruber, M.4
Cortez-Retamozo, V.5
Panizzi, P.6
Figueiredo, J.L.7
Kohler, R.H.8
Chudnovskiy, A.9
Waterman, P.10
-
37
-
-
77950960449
-
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease
-
Van de Veire S., Stalmans I., Heindryckx F., Oura H., Tijeras-Raballand A., Schmidt T., Loges S., Albrecht I., Jonckx B., Vinckier S., et al. Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell 2010, 141:178-190.
-
(2010)
Cell
, vol.141
, pp. 178-190
-
-
Van de Veire, S.1
Stalmans, I.2
Heindryckx, F.3
Oura, H.4
Tijeras-Raballand, A.5
Schmidt, T.6
Loges, S.7
Albrecht, I.8
Jonckx, B.9
Vinckier, S.10
-
38
-
-
0035913903
-
HSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H., Dessain S.K., Ng Eaton E., Imai S.I., Frye R.A., Pandita T.K., Guarente L., Weinberg R.A. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 2001, 107:149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
39
-
-
78650711240
-
Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension
-
Vinh A., Chen W., Blinder Y., Weiss D., Taylor W.R., Goronzy J.J., Weyand C.M., Harrison D.G., Guzik T.J. Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension. Circulation 2010, 122:2529-2537.
-
(2010)
Circulation
, vol.122
, pp. 2529-2537
-
-
Vinh, A.1
Chen, W.2
Blinder, Y.3
Weiss, D.4
Taylor, W.R.5
Goronzy, J.J.6
Weyand, C.M.7
Harrison, D.G.8
Guzik, T.J.9
-
40
-
-
80052961896
-
Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction
-
Wenzel P., Knorr M., Kossmann S., Stratmann J., Hausding M., Schuhmacher S., Karbach S.H., Schwenk M., Yogev N., Schulz E., et al. Lysozyme M-positive monocytes mediate angiotensin II-induced arterial hypertension and vascular dysfunction. Circulation 2011, 124:1370-1381.
-
(2011)
Circulation
, vol.124
, pp. 1370-1381
-
-
Wenzel, P.1
Knorr, M.2
Kossmann, S.3
Stratmann, J.4
Hausding, M.5
Schuhmacher, S.6
Karbach, S.H.7
Schwenk, M.8
Yogev, N.9
Schulz, E.10
-
41
-
-
0005183084
-
Electrical stimulation of preganglionic nerve increases tyrosine hydroxylase activity in sympathetic ganglia
-
Zigmond R.E., Ben-Ari Y. Electrical stimulation of preganglionic nerve increases tyrosine hydroxylase activity in sympathetic ganglia. Proc. Natl. Acad. Sci. USA 1977, 74:3078-3080.
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 3078-3080
-
-
Zigmond, R.E.1
Ben-Ari, Y.2
|