Perinatal Exposure to Lead: Reduction in Alterations of Brain Mitochondrial Antioxidant System with Calcium Supplement

Biological Trace Element Research

Volumn 162, Issue 1-3, 2014, Pages 270-277

  Gottipolu, Rajarami Reddy ^a   Davuljigari, Chand Basha ^a  

^a SRI VENKATESWARA UNIVERSITY   (India)

Author keywords

Calcium supplementation; Cerebellum; Hippocampus; Lead toxicity; Oxidative stress

Indexed keywords

ANTIOXIDANT; CALCIUM; CATALASE; CERULOPLASMIN OXIDASE; COPPER ZINC SUPEROXIDE DISMUTASE; DRINKING WATER; GLUTATHIONE PEROXIDASE; LEAD ACETATE; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL ENZYME; OXIDOREDUCTASE; UNCLASSIFIED DRUG; XANTHINE OXIDASE; LEAD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; BRAIN PROTECTION; BRAIN TOXICITY; BREAST MILK; CEREBELLUM; CERULOPLASMIN OXIDASE BLOOD LEVEL; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; GESTATION PERIOD; HIPPOCAMPUS; LEAD POISONING; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; PERINATAL PERIOD; PRENATAL EXPOSURE; RAT; ANIMAL; BRAIN; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PREGNANCY;

ANIMALS; ANTIOXIDANTS; BRAIN; CALCIUM; DIETARY SUPPLEMENTS; FEMALE; HIPPOCAMPUS; LEAD; MALE; MALONDIALDEHYDE; MITOCHONDRIA; OXIDATIVE STRESS; PREGNANCY; RATS;

EID: 84912029739     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-014-0112-7     Document Type: Article

References (43)

1. Toscano CD, Guilarte TR (2005) Lead neurotoxicity: from exposure to molecular effects. Brain Res Brain Res Rev 49(3):529–554
2. Flora G, Gupta D, Tiwari A (2012) Toxicity of lead: a review with recent updates. Interdiscip Toxicol 5(2):47–58
3. Niu RY, Sun SI, Cheng ST, Li ZG, Wang JD (2009) Decreased learning ability and low hippocampus glutamate in offspring rats exposed to fluoride and lead. Environ Toxicol Pharmacol 28:254–258
4. Needleman H (2009) Low level lead exposure: history and discovery. Ann Epidemiol 19(4):235–238
5. Hu A, Fu H, Ren T, Wang S, Zhou W, Song H et al (2008) Maternal low level lead exposure reduces the expression of PSA-NCAM and the activity of sialyl transferase in the hippocampi of neonatal rat pups. Neurotoxicology 29:675–681
6. Shakila T, Hsiu-Jen W, Joshua WC, William AB, Nuran E (2014) Effects of lead and cadmium on brain endothelial cell survival, monolayer permeability, and crucial oxidative stress markers in an in vitro model of the blood-brain barrier. Toxics 2(2):258–275
7. Yin ST, Tang ML, Su L, Chen L, Hu P, Wang HL et al (2008) Effects of epigallocatechin-3-gallate on lead -induced oxidative damage. Toxicology 249:45–54
8. Prasanthi RPJ, Devi CB, Basha DC, Reddy NS, Reddy GR (2010) Calcium and zinc supplementation protects lead (Pb)-induced perturbations in antioxidant enzymes and lipid peroxidation in developing mouse brain. Int J Dev Neurosci 28:161–167
9. Wang Q, Luo W, Zheng W, Liu Y, Xu H, Zheng G, Dai Z, Zhang W, Chen Y, Chen J (2007) Iron supplement prevents lead-induced disruption of the blood-brain barrier during rat development. Toxicol Appl Pharmacol 219:33–41
10. Basha DC, Rani UM, Devi CB, Kumar MR, Reddy GR (2012) Perinatal lead exposure alters postnatal cholinergic and aminergic system in rat brain: reversal effect of calcium co-administration. Int J Dev Neurosci 30:343–350
11. Nazıroğlu M (2011) TRPM2 cation channels, oxidative stress and neurological diseases: where are we now? Neurochem Res 36(3):355–366
12. Nazıroğlu M, Senol N, Ghazizadeh V, Yürüker V (2014) Neuroprotection induced by N-acetylcysteine and selenium against traumatic brain injury-induced apoptosis and calcium entry in hippocampus of rat. Cell Mol Neurobiol 34(6):895–903
13. Prasanthi RPJ, Reddy GH, Reddy GR (2006) Calcium and zinc supplementation reduces lead toxicity: assessment of behavioral dysfunctions in young and adult mice. Nutr Res 26:537–545
14. Cotman CW, Matthews DA (1971) Synaptic plasma membranes from rat brain synaptosomes: isolation and partial characterization. Biochem Biophys Acta 249:380–394
15. Schosinsky KH, Lehmann HP, Beeler MF (1974) Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride. Clin Chem 20:1556–1563
16. Misra HP, Fridovich I (1972) The role of superoxide anion in the autooxidation of epinephrine and a simple assay for Superoxide dismutase. J Biol Chem 247:3170–3175
17. Tappel ME, Chaudiere J, Tappel AL (1982) Glutathione peroxidase activities of animal tissues. Comp Biochem Physiol 73:945–949
18. Beers RF, Sizer IW (1952) A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 195:133–140
19. Worthington Manual (2004) Xanthine oxidase assay. Worthington Biochemical Corporation, USA, pp 399–401
20. Hiroshi O, Ohisi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by TBA reaction. Anal Biochem 95:351–358
21. Lowry OH, Rosenbrough NJ, Farr AL, Randal RJ (1951) Protein measurement with Folin phenol reagent. J Biol Chem 193:265–275
22. Okado-Matsumoto A, Fridovich I (2001) Assay of superoxide dismutase: cautions relevant to the use of cytochrome c, a sulfonated tetrazolium, and cyanide. Anal Biochem 298(2):337–342
23. Liu CM, Zheng YL, Lu J, Zhang ZF, Fan SH, Wu DM, Ma JQ (2010) Quercetin protects rat liver against lead-induced oxidative stress and apoptosis. Environ Toxicol Pharmacol 29:158–166
24. Ahamed M, Siddiqui MK (2007) Low level lead exposure and oxidative stress: current opinions. Clin Chim Acta 383(1–2):57–64
25. Sivaprasad R, Nagaraj M, Varalakshmi P (2002) Lipoic acid in combination with a chelator ameliorates lead-induced peroxidative damages in rat kidney. Arch Toxicol 76(8):437–441
26. Newairy AS, Abdou HM (2009) Protective role of flax lignans against lead acetate induced oxidative damage and hyperlipidemia in rats. Food Chem Toxicol 47(4):813–818
27. Jaako-Movits K, Zharkovsky T, Romantchik O, Jurgenson M, Merisalu E, Heidmets LT, Zharkovsky A (2005) Developmental lead exposure impairs contextual fear conditioning and reduces adult hippocampal neurogenesis in the rat brain. Int J Dev Neurosci 23(7):627–635
28. Armstrong JS, Jones DP (2002) Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2-overexpressing HL60 cells. FASEB J 16:1263–1265
29. Chaurasia SS, Kar A (1997) Protective effects of vitamin E against lead-induced deterioration of membrane associated type-I iodothyronine 5′-monodeiodinase (5′D-I) activity in male mice. Toxicology 124(3):203–209
30. Xia D, Yu X, Liao S, Shao Q, Mou H, Ma W (2010) Protective effect of Smilax glabra extract against lead-induced oxidative stress in rats. J Ethnopharmacol 130(2):414–420
31. Harris ZL, Takahashi Y, Miyajima H, Serizawa M, Mac Gillivray RT, Gitlin JD (1995) A ceruloplasmi nemi a: molecular characterization of this disorder of iron metabolism. Proc Natl Acad Sci USA 92(7):2539–2543
32. Aksoy H, Taysi S, Altınkaynak K, Bakan E, Bakan N, Kumtepe Y (2003) Anti oxidant potential and transferrin, ceruloplasmin and lipidperoxidation levels in women with pre eclampsia. J Investig Med 51(5):284–287
33. Böyük A, öztekin C, Behçet al, a. Ahmet B, Taysi S (2010) Serum ceruloplasmin oxidase activity and malondialdehyde level in experimental abdominal compartment syndrome-induced rats. Turkiye Klinikleri J Med Sci 30(2)
34. Rendón-Ramírez AL, Maldonado-Vega M, Quintanar-Escorza MA, Hernández G, Arévalo-Rivas BI, Zentella-Dehesa A, Calderón-Salinas JV (2014) Effect of vitamin E and C supplementation on oxidative damage and total antioxidant capacity in lead-exposed workers. Environ Toxicol Pharmacol 37(1):45–54
35. Sandhir R, Gill KD (1994) Lead perturbs calmodulin dependent cyclic AMP metabolism in rat central nervous system. Biochem Mol Biol Int 33(4):729–742
36. Klivenyi P, Andreassen OA, Ferrante RJ, Dedeoglu A, Mueller G, Lancelot E, Bogdanov M, Andersen JK, Jiang D, Beal MF (2000) Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. J Neurosci 20(1):1–7
37. Kodavanti PRS (1999) Reactive oxygen species and antioxidant homeostasis in neurotoxicology. In: Tilson HA, Harry G (eds) Neurotoxicology. Target Organ Toxicology Series. Taylor and Francis, Philadelphia, pp 157–178
38. Struzyńska L, Sułkowski G, Lenkiewicz A, Rafałowska U (2002) Lead stimulates the glutathione system in selective regions of rat brain. Folia Neuropathol 40(4):203–209
39. Zawia NH, Harry GJ (1996) Developmental exposure to lead interferes with glial and neuronal differential gene expression in the rat cerebellum. Toxicol Appl Pharmacol 138(1):43–47
40. Dorea JG, Donangelo CM (2006) Early (in uterus and infant) exposure to mercury and lead. Clin Nutr 25(3):369–376
41. Bruckbauer A, Zemel MB (2009) Dietary calcium and dairy modulation of oxidative stress and mortality in aP2-agouti and wild-type mice. Nutrients 1(1):50–70
42. Flora SJ, Saxena G, Mehta A (2007) Reversal of lead-induced neuronal apoptosis by chelation treatment in rats: role of reactive oxygen species and intracellular Ca (2+). J Pharmacol Exp Ther 322(1):108–116
43. Ettinger AS, Lamadrid-Figueroa H, Téllez-Rojo MM, Mercado-García A, Peterson KE, Schwartz J, Hu H, Hernández-Avila M (2009) Effect of calcium supplementation on blood lead levels in pregnancy: a randomized placebo-controlled trial. Environ Health Perspect 117(1):26–31