Plasma miRNA levels correlate with sensitivity to bone mineral density in postmenopausal osteoporosis patients

Biomarkers

Volumn 19, Issue 7, 2014, Pages 553-556

  Li, Hongqiu ^a   Wang, Zhe ^a   Fu, Qin ^a   Zhang, Jing ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Bone mineral density; MiRNA; Osteoporosis; Postmenopausal

Indexed keywords

MICRORNA; MICRORNA 133A; MICRORNA 146A; MICRORNA 21; UNCLASSIFIED DRUG; GENETIC MARKER; MIRN133 MICRORNA, HUMAN; MIRN146 MICRORNA, HUMAN; MIRN21 MICRORNA, HUMAN;

ADULT; AGED; ARTICLE; BONE DENSITY; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; OSTEOPENIA; OSTEOPOROSIS; POSTMENOPAUSE; POSTMENOPAUSE OSTEOPOROSIS; PROTEIN EXPRESSION; UPREGULATION; BLOOD; CASE CONTROL STUDY; GENETIC MARKER; GENETICS; METABOLIC BONE DISEASE; MIDDLE AGED; PATHOLOGY; PREDICTIVE VALUE; REAL TIME POLYMERASE CHAIN REACTION;

AGED; BONE DENSITY; BONE DISEASES, METABOLIC; CASE-CONTROL STUDIES; FEMALE; GENETIC MARKERS; HUMANS; MICRORNAS; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; PREDICTIVE VALUE OF TESTS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84912009720     PISSN: 1354750X     EISSN: 13665804     Source Type: Journal    
DOI: 10.3109/1354750X.2014.935957     Document Type: Article

References (23)

1. Bartel DP. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-97.
2. Blondal T, Jensby Nielsen S, Baker A, et al. (2013). Assessing sample and miRNA profile quality in serum and plasma or other biofluids. Methods 59:S1-6.
3. Cummings SR, Melton LJ. (2002). Epidemiology and outcomes of osteoporotic fractures. Lancet 359:1761-7.
4. Khosla S, Melton LJ, Riggs BL. (2011). The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: is a revision needed? J Bone Miner Res 26:441-51
5. Kishimoto T, Eguchi H, Nagano H, et al. (2013). Plasma miR-21 is a novel diagnostic biomarker for biliary tract cancer. Cancer Sci 104: 1626-31.
6. Lei SF, Papasian CJ, Deng HW. (2011). Polymorphisms in predicted miRNA binding sites and osteoporosis. J Bone Miner Res 26:72-8.
7. Levine JP. (2011). Identification, diagnosis, and prevention of osteoporosis. Am J Manag Care 17:S170-6.
8. Murata K, Furu M, Yoshitomi H, et al. (2013). Comprehensive microRNA analysis identifies miR-24 and miR-125a-5p as plasma biomarkers for rheumatoid arthritis. PLoS One 8:e69118.
9. Mizoguchi F, Izu Y, Hayata T, et al. (2010). Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption. J Cell Biochem 109:866-75.
10. Ouyang L, Liu P, Yang S, et al. (2013). A three-plasma miRNA signature serves as novel biomarkers for osteosarcoma. Med Oncol 30:340-7.
11. Sambrook P, Cooper C. (2004). Osteoporosis. Lancet 367:2010-18.
12. Seeliger C, Karpinski K, Haug A, et al. (2014). Five freely circulating miRNAs and bone tissue miRNAs are associated with osteoporotic fractures. J Bone Miner Res 29:1718-28.
13. Singh A, Ali S, Mahdi Abbas A, Srivastava RN. (2013). Evaluation of role of microRNA in osteoporosis. J Pharm Biomed Sci 33: 1439-48.
14. Sugatani T, Hruska KA. (2009). Impaired micro-RNA pathways diminish osteoclast differentiation and function. J Biol Chem 284: 4667-78.
15. Taipaleenmäki H, Bjerre Hokland L, Chen L, et al. (2012). Mechanisms in endocrinology: micro-RNAs: targets for enhancing osteoblast differentiation and bone formation. Eur J Endocrinol 166:359-71.
16. van Wijnen AJ, van de Peppel J, van Leeuwen JP. (2013). MicroRNA functions in osteogenesis and dysfunctions in osteoporosis. Curr Osteoporos Rep 11:72-82.
17. Wang K, Zhang S, Weber J, et al. (2010). Export of microRNAs and microRNA-protective protein by mammalian cells. Nucleic Acids Res 38:7248-59.
18. Wang Y, Li L, Moore BT, et al. (2012). MiR-133a in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis. PLoS One 7:e34641.
19. Xia Z, Chen C, Chen P, et al. (2011). MicroRNAs and their roles in osteoclast differentiation. Front Med 5:414-19.
20. Yang N, Wang G, Hu C, et al. (2013). Tumor necrosis factor a suppresses the mesenchymal stem cell osteogenesis promoter miR-21 in estrogen deficiency-induced osteoporosis. J Bone Miner Res 28: 559-73.
21. Yuan J, Chen L, Chen X, et al. (2012). Identification of serum microRNA-21 as a biomarker for chemosensitivity and prognosis in human osteosarcoma. J Int Med Res 40:2090-7.
22. Zeng Z, Wang J, Zhao L, et al. (2013). Potential role of microRNA-21 in the diagnosis of gastric cancer: a meta-analysis. PLoS One 8: e73278.
23. Zhao D, Tu Y, Wan L, et al. (2013). In vivo monitoring of angiogenesis inhibition via down-regulation of mir-21 in a VEGFR2-luc murine breast cancer model using bioluminescent imaging. PLoS One 8: e71472.