In Vivo Monitoring of Angiogenesis Inhibition via Down-Regulation of Mir-21 in a VEGFR2-Luc Murine Breast Cancer Model Using Bioluminescent Imaging

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Zhao, Dongliang ^a,b   Tu, Yingfeng ^a,b   Wan, Lin ^a,b   Bu, Lihong ^a,b   Huang, Tao ^a,b   Sun, Xilin ^a,b   Wang, Kai ^a,b   Shen, Baozhong ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b China Key Laboratory of Chemical Engineering Process and Technology for High Efficiency   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTAGOMIR; ANTAGOMIR 21; CASPASE 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA 21; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; UNCLASSIFIED DRUG; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BIOLUMINESCENCE IMAGING; BREAST CANCER; CANCER CELL; CANCER INHIBITION; CAPILLARY DENSITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR IMAGING; MOUSE; NICK END LABELING; NON INVASIVE MEASUREMENT; NONHUMAN; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR VOLUME; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; ANIMALS; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; DOWN-REGULATION; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MICE; MICE, TRANSGENIC; MICRORNAS; NEOVASCULARIZATION, PATHOLOGIC; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84881338063     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071472     Document Type: Article

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