Characterization and genotyping of the DRB1 gene of the major histocompatibility complex (MHC) in the Marmota monax, animal model of hepatitis B

Molecular Immunology

Volumn 63, Issue 2, 2015, Pages 505-512

  Moreno Cugnon, Leire ^a   Esparza Baquer, Aitor ^a   Larruskain, Amaia ^a,d   García Etxebarria, Koldo ^a   Menne, Stephan ^b   González Aseguinolaza, Gloria ^c   Jugo, Begoña M ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF NAVARRA   (Spain)

^d Progenika Biopharma SA   (Spain)

Author keywords

Antigen binding site; DRB1 gene; Duplication; Hepatitis B virus; Major histocompatibility complex; Positive selection

Indexed keywords

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY COMBINING SITE; ARTICLE; DRB1 GENE; DRB1A GENE; DRB1B GENE; EXON; GENE; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC VARIABILITY; GENOTYPE; HEPATITIS B; HETEROZYGOSITY; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; WOODCHUCK; WOODCHUCK HEPATITIS; WOODCHUCK HEPATITIS VIRUS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DISEASE MODEL; DNA SEQUENCE; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; MARMOTA; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; PHYLOGENY; PHYSIOLOGY; SEQUENCE ALIGNMENT; VIROLOGY;

ANIMALIA; HEPATITIS B VIRUS; MARMOTA MONAX;

HLA DRB1 ANTIGEN; PRIMER DNA;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; DISEASE MODELS, ANIMAL; DNA PRIMERS; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS, WOODCHUCK; HLA-DRB1 CHAINS; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MARMOTA; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

EID: 84912006402     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2014.10.011     Document Type: Article

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