A simple new method for estimating null allele frequency from heterozygote deficiency

Molecular Ecology

Volumn 5, Issue 3, 1996, Pages 453-455

  Brookfield, J F Y ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

DNA profiles; Heterozygote deficiency; Maximum likelihood estimation; Null alleles

Indexed keywords

ALLELE; ANIMAL; ARTICLE; BIOLOGICAL MODEL; GENE DELETION; GENE FREQUENCY; GENETIC PROCEDURES; HETEROZYGOTE; HUMAN; MATHEMATICS; PROBABILITY; STATISTICAL MODEL;

ALLELES; ANIMALS; GENE DELETION; GENE FREQUENCY; GENETIC TECHNIQUES; HETEROZYGOTE; HUMANS; MATHEMATICS; MODELS, GENETIC; MODELS, STATISTICAL; PROBABILITY;

EID: 0030171429     PISSN: 09621083     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-294X.1996.tb00336.x     Document Type: Article

References (6)

1. Callen DF, Thompson AD, Shen Y, Phillips H, Richards RI, Mulley JC, Sutherland GR (1993) Incidence and origin of 'null' alleles in the (AC)n microsatellite markers. American Journal of Human Genetics, 52, 922-927.
2. Chakraborty R, De Andrade M, Daiger SP, Budowle B (1992) Apparent heterozygote deficiencies observed in DNA typing data and their implications in forensic applications. Annals of Human Genetics, 56, 45-57.
3. Chakraborty R, Zhong Y, Jin L, Budowle B (1994) Nondetectability of restriction fragments and independence of DNA fragment sizes within and between loci in RFLP typing of DNA. American Journal of Human Genetics, 55, 391-401.
4. Foltz DJ (1986) Null alleles as a possible cause of heterozygote deficiencies in the oyster Crassostrea virginica and other bivalves. Evolution, 40, 869-870.
5. Neumann K, Wetton JH (1996) Highly polymorphic microsatellites in the house sparrow (Passer domesticus). Molecular Ecology, in press.
6. Pemberton JM, Slate J, Bancroft DR, Barrett JA (1995) Non-amplifying alleles at microsatellite loci: a caution for parentage and population studies. Molecular Ecology, 4, 249-252.