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This study presents data related to tick bites inducing the IgE Ab response to alpha-gal. The report is the first example of a response to an ectoparasite giving rise to an important form of food allergy. The results also document that tick bites can induce high titers of IgE antibodies to a single oligosaccharide epitope
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COI: 1:CAS:528:DC%2BC2cXht1ajtbbK, PID: 24750173, The prevalence of sIgE to alpha-gal has not been a lingering question. The prevalence of alpha-gal sIgE antibodies in two general adult European populations (Denmark and Spain) was found to be 5.5 and 8.1 %, respectively. The presence of alpha-gal sIgE antibodies was associated with a history of tick bites, atopy, and cat ownership
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