Immunogenic glycoconjugates implicated in parasitic nematode diseases

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1455, Issue 2-3, 1999, Pages 353-362

  Dell, Anne ^a   Haslam, Stuart M ^a   Morris, Howard R ^a   Khoo, Kay Hooi ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

Antigen; Glycoconjugate; Nematode; Structure

Indexed keywords

EPITOPE; GLYCAN; GLYCOCONJUGATE; PARASITE ANTIGEN; PHOSPHORYLCHOLINE;

CUTICLE; FUCOSYLATION; GLYCOCALYX; GLYCOSYLATION; HOST PARASITE INTERACTION; HUMAN; IMMUNOGENICITY; METHYLATION; NEMATODE; NEMATODIASIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; TOXOCARA;

ANIMALS; CARBOHYDRATE SEQUENCE; EPITOPES; HEXOSES; MOLECULAR SEQUENCE DATA; NEMATODE INFECTIONS; TOXOCARA;

NEMATODA;

EID: 0032834853     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(99)00064-2     Document Type: Review

References (54)

1. Allen J.E., Maizels R.M. Immunology of human helminth infection. Int. Arch. Allergy Immunol. 109:1996;3-10.
2. Ashman K., Mather J., Wiltshire C., Jacobs H.J., Meeusen E. Isolation of a larval surface glycoprotein from Haemonchus contortus and its possible role in evading host immunity. Mol. Biochem. Parasitol. 70:1995;175-179.
3. Blaxter M.L., Page A.P., Rudin W., Maizels R.M. Nematode surface coats: actively evading immunity. Parasitol. Today. 8:1992;243-247.
4. Bürglin T.R., Lobos E., Blaxter M.L. Caenorhabditis elegans as a model for parasitic nematodes. Int. J. Parasitol. 28:1998;395-411.
5. Chan M.-S. The global burden of intestinal nematode infections - fifty years on. Parasitol. Today. 13:1997;438-443.
6. R.D. Cummings, A.K. Nyame, Schistosome glycoconjugates, this volume (1999).
7. DeBose-Boyd R.A., Nyame A.K., Cummings R.D. Molecular cloning and characterization of an α1,3 fucosyltransferase, CEFT-1 from Caenorhabditis elegans. Glycobiology. 8:1998;905-917.
8. Deehan M.R., Frame M.J., Parkhousr R.M.E., Seatter S.D., Reid S.D., Harnett M.M., Harnett W. A filarial nematode secreted product differentially modulates expression and activation of protein kinase C isoforms in B lymphocytes. J. Immunol. 160:1998;2692-2699.
9. Ellis L.A., McVay C.S., Probert M.A., Zhang J., Bundle D.R., Appleton J.A. Terminal β-linked tyvelose creates unique epitopes in Trichinella spiralis glycan antigens. Glycobiology. 7:1997;383-390.
10. Finkelman F.D., Shea-Donohue T., Golhill J., Sullivan C.A., Morris S.C., Madden K.B., Gause W.C., Urban J.F. Jr. Cytokine regulation of host defense against parasitic gastrointestinal nematodes: lessons from studies with rodent models. Annu. Rev. Immunol. 15:1997;505.
11. Freedman D.O. Immune dynamics in the pathogenesis of human lymphatic filariasis. Parasitol. Today. 14:1998;229-234.
12. Gems D., Maizels R.M. An abundantly expressed mucin-like protein from Toxocara canis infective larvae: The precursor of the larval surface coat glycoproteins. Proc. Natl. Acad. Sci. USA. 93:1996;1665-1670.
13. Gillespie S.H. The epidemiology and pathogenesis of zoonotic toxocariasis. Parasitol. Today. 4:1988;180-182.
14. Grencis R.K. Th2-mediated host protective immunity to intestinal nematode infections. Phil. Trans. R. Soc. Lond. B Biol. Sci. 352:1997;1377-1384.
15. Hagen F.K., Nehrke K. cDNA cloning and expression of a family of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase sequence homologs from Caenorhabditis elegans. J. Biol. Chem. 273:1998;8268-8277.
16. Harnett W., Harnett M.M. Inhibition of murine B cell proliferation and down-regulation of protein Kinase C levels by a phosphorylcholine-containing filarial excretory-secretory product. J. Immunol. 151:1993;4829-4837.
17. Harnett W., Houston K.M., Amess R., Worms M.J. Acanthocheilonema viteae: phosphorylcholine is attached to the major excretory-secretory product via a N-linked glycan. Exp. Parasitol. 77:1993;498-502.
18. M.M. Harnett, M.R. Deehan, D.W. Williams, W. Harnett, Induction of signaling anergy via the TCR in Jurkat T cells by pre-exposure to a filarial nematode secreted product, Parasite Immunol. (1998) in press.
19. Haslam S.M., Coles G.C., Munn E.A., Smith T.S., Smith H.F., Morris H.R., Dell A. Haemonchus contortus glycoproteins contain N-linked oligosaccharides with novel highly fucosylated core structures. J. Biol. Chem. 271:1996;30561-30570.
20. Haslam S.M., Khoo K.-H., Houston K.M., Harnett W., Morris H.R., Dell A. Characterisation of the phosphorylcholine-containing N-linked oligosaccharides in the excretory-secretory 62 kDa glycoprotein of Acanthocheilonema viteae. Mol. Biochem. Parasitol. 85:1997;53-66.
21. Haslam S.M., Coles G.C., Reason A.J., Morris H.R., Dell A. The novel core fucosylation of Haemonchus contortus N-glycans is stage specific. Mol. Biochem. Parasitol. 93:1998;143-147.
22. Kang S., Cummings R.D., McCall J.W. Characterization of the N-linked oligosaccharides in glycoproteins synthesised by microfilariae of Dirofilaria immitis. J. Parasitol. 79:1993;815-828.
23. Kennedy M.W., Maizels R.M., Meghji M., Young L., Qureshi F., Smith H.V. Species-specific and common epitopes on the secreted and surface antigens of Toxocara cati and Toxocara canis infective larvae. Parasite Immunol. 9:1987;407-420.
24. Kennedy M.W., Qureshi F., Fraser E.M., Haswell-Elkins M.R., Elkins D.B., Smith H.V. Antigenic relationships between the surface-exposed, secreted and somatic materials of the nematode parasites Ascaris lumbricoides, Ascaris suum and Toxocara canis. Clin. Exp. Immunol. 75:1989;493-500.
25. Khoo K.-H., Maizels R.M., Page A.P., Taylor G.W., Rendell N.B., Dell A. Characterization of nematode glycoproteins: The major O-glycans of Toxocara excretory-secretory antigens are O-methylated trisaccharides. Glycobiology. 1:1991;163-171.
26. K.-H. Khoo, H.R. Morris, A. Dell, Structural characterisation of the major glycans of Toxocara canis ES antigens, in: J.W. Lewis, R.M. Maizels (Eds.), Toxocara and Toxocariasis: Clinical, Epidemiological and Molecular Perspectives. Institute of Biology, 1993.
27. 2. Eur. J. Biochem. 213:1993;1193-1204.
28. Lightowlers M.W., Rickard M.D. Excretory-secretory products of helminth parasites: effects on host immune responses. Parasitology. 96:1988;S123-S166.
29. Lochnit G., Dennis R.D., Ulmer A.J., Geyer R. Structural elucidation and monokine-inducing activity of two biologically active zwitterionic glycosphingolipids derived from the porcine parasitic nematode Ascaris suum. J. Biol. Chem. 273:1998;466-474.
30. Lochnit G., Nispel S., Dennis R.D., Geyer R. Structural analysis and immunohistochemical location of two glycosphingolipids from the porcine parasitic nematode Ascaris suum. Glycobiology. 8:1998;891-899.
31. Maizels R.M., Kennedy M.W., Meghji M., Robertson B.D., Smith H.V. Shared carbohydrate epitopes on distinct surface and secreted epitopes of the parasitic nematode Toxocara canis. J. Immunol. 139:1987;207-214.
32. R.M. Maizels, A.E. Bianco, J.E. Flint, W.F. Gregory, M.W. Kennedy, G.E. Lim, B.D. Robertson, M.E. Selkirk, Glycoconjugate antigens from parasitic nematodes, in: A.J. MacInnis (Ed.), Molecular Paradigms for Eradicating Helminthic Parasites, Alan R. Liss, New York, 1987b, pp. 267-279.
33. Maizels R.M., Burke L., Denham D.A. Phosphorylcholine-bearing antigens in filarial nematode parasites: analysis of somatic extracts, in-vitro secretions and infection sera from Brugia malayi and B. pahangi. Parasite Immunol. 9:1987;49-66.
34. R.M. Maizels, M.E. Selkirk, Immunobiology of nematode antigens, in: P.T. Englund, F.A. Sher (Eds.), The Biology of Parasitism, Alan R. Liss, New York, 1988, pp. 285-308.
35. R.M. Maizels, B.D. Robertson, Toxocara canis: secreted glycoconjugate antigens in immunobiology and immunodiagnosis, in: M.W. Kennedy (Ed.), Parasitic Nematodes: Antigens, Membranes and Genes, Taylor and Francis, London, 1990, pp. 95-115.
36. Maizels R.M., Page A.P. Surface associated glycoproteins from Toxocara canis larval parasites. Acta Trop. 47:1990;355-364.
37. Maizels R.M., Bundy D.A.P., Selkirk M.E., Smith D.F., Anderson R.M. Immunological modulation and evasion by helminth parasites in human populations. Nature. 365:1993;797-805.
38. McCarthy J.S., Nutman T.B. Perspective: prospects for development of vaccines against human helminth infections. J. Infect. Dis. 174:1996;1384-1390.
39. McVay C.S., Tsung A., Appleton J.A. Participation of parasite surface glycoproteins in antibody-mediated protection of epithelial cells against Trichinella spiralis. Infect. Immun. 66:1998;1941-1945.
40. Michael E., Bundy D.A., Grenfell B.T. Re-assessing the global prevalence and distribution of lymphatic filariasis. Parasitology. 112:1996;409-428.
41. Molyneux D.H., Davies J.B. Onchocerciasis control: moving towards the millennium. Parasitol. Today. 13:1997;418-424.
42. x expression in other trematodes and nematodes. Glycobiology. 8:1998;615-624.
43. Otubu O.E., Carlisle-Nowak M.S., McGregor D.D., Jacobson R.H., Appleton J.A. Trichinella spiralis: the effect of specific antibody on muscle larvae in the small intestines of weaned rats. Exp. Parasitol. 76:1993;394-400.
44. 2: the role of α1,3-fucosylation of the asparagine bound N-acetylglucosamine. Biochem. J. 284:1992;377-380.
45. D.I. Pritchard, C. Hewitt, R. Moqbel, The relationship between immunological responsiveness controlled by T-helper 2 lymphocytes and infections with parasitic helminths, Parasitology 115, Suppl. (1997) S33-S44.
46. Raleigh J.M., Meeusen E.N.T. Developmentally regulated expression of a Haemonchus contortus surface antigen. Int. J. Parasitol. 26:1996;673-675.
47. Raleigh J.M., Brandon M.R., Meeusen E. Stage-specific expression of surface molecules by the larval stages of Haemonchus contortus. Parasite Immunol. 18:1996;125-132.
48. Ramirez-Soto D., Poretz R.D. The (1-3)-linked α-L-fucosyl group of the N-glycans of the Wistaria floribunda lectin is recognised by a rabbit antiserum. Carbohydr. Res. 213:1991;27-36.
49. Reason A.J., Ellis L.A., Appleton J.A., Wisnewski N., Grieve R.B., McNeil M., Wassom D.L., Morris H.R., Dell A. Novel tyvelose-containing tri- and tetra-antennary N-glycans in the immunodominant antigens of the intracellular parasite Trichinella spiralis. Glycobiology. 4:1994;593-603.
50. M.R.H. Taylor, C.T. Keane, P. O'Connor, E. Mulvihill, C. Holland, The expanded spectrum of toxocaral disease, Lancet i (1988) 692-695.
51. Vassilatis D.K., Polvere R.I., Despommier D.D., Gold A.M., Van der Ploeg L.H.T. Developmental expression of a 43-kDa secreted glycoprotein from Trichinella spiralis. Mol. Biochem. Parasitol. 78:1996;13-23.
52. 2. Allergy. 42:1987;464-470.
53. Wilson I.B.H., Harthill J.E., Mullin N.P., Ashford D.A., Altmann F. Core α1,3-fucose is a key part of the epitope recognized by antibodies reacting against plant N-linked oligosaccharides and is present in a wide variety of plant extracts. Glycobiology. 8:1998;651-661.
54. Wisnewski N., McNeil M., Grieve R.B., Wassom D.L. Characterisation of novel fucosyl- and tyvelosyl-containing glycoconjugates from Trichinella spiralis muscle stage larvae. Mol. Biochem. Parasitol. 61:1993;25-36.