KN-93, an inhibitor of calcium/calmodulin-dependent protein kinase IV, promotes generation and function of Foxp3+ regulatory T cells in MRL/lpr mice

Autoimmunity

Volumn 47, Issue 7, 2014, Pages 445-450

  Koga, Tomohiro ^a   Mizui, Masayuki ^a   Yoshida, Nobuya ^a   Otomo, Kotaro ^a   Lieberman, Linda A ^a   Crispín, José C ^a   Tsokos, George C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calcium calmodulin dependent protein kinase IV; KN 93; Organ damage; Regulatory T cells; Systemic lupus erythematosus

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE; INTERLEUKIN 2; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; TRANSCRIPTION FACTOR FOXP3; BENZYLAMINE DERIVATIVE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE IV; CAMK4 PROTEIN, MOUSE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; INFLAMMATORY CELL; KIDNEY DISEASE; KIDNEY INJURY; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SKIN DISEASE; SYSTEMIC LUPUS ERYTHEMATOSUS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL COUNT; CONVALESCENCE; DRUG EFFECTS; ENZYMOLOGY; IMMUNOLOGY; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE;

ANIMALS; BENZYLAMINES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 4; CELL COUNT; FORKHEAD TRANSCRIPTION FACTORS; INTERLEUKIN-2; LUPUS ERYTHEMATOSUS, SYSTEMIC; MICE, INBRED MRL LPR; PROTEIN KINASE INHIBITORS; RECOVERY OF FUNCTION; SULFONAMIDES; T-LYMPHOCYTES, REGULATORY;

EID: 84911999334     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2014.915954     Document Type: Article

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