Antinociceptive effects of combination of Tramadol and Acetaminophen on painful diabetic neuropathy in streptozotocin-induced diabetic rats

Acta Anaesthesiologica Taiwanica

Volumn 49, Issue 1, 2011, Pages 16-20

  Gong, Ya Hong ^a   Yu, Xue Rong ^a   Liu, Hui Li ^b   Yang, Nan ^c   Zuo, Ping Ping ^c   Huang, Yu Guang ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

^c INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

acetaminophen; diabetes mellitus; drug interactions; pain: neuropathic; Tramadol

Indexed keywords

PARACETAMOL; PARACETAMOL PLUS TRAMADOL; STREPTOZOCIN; TRAMADOL;

ALGOMETER; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; ELECTRONIC VON FREY TEST; EXPERIMENTAL TEST; HOT PLATE TEST; HYPERALGESIA; HYPERGLYCEMIA; MALE; NONHUMAN; PAIN THRESHOLD; RANDOMIZED CONTROLLED TRIAL; RAT; SINGLE DRUG DOSE; STREPTOZOCIN DIABETES; TAIL FLICK TEST;

ACETAMINOPHEN; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; DRUG THERAPY, COMBINATION; MALE; PAIN; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; TRAMADOL;

EID: 79953275338     PISSN: 18754597     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aat.2011.01.003     Document Type: Article

References (30)

1. Jensen TS, Backonja MM, Hernandez JS, Tesfaye S, Valensi P, Ziegler D. New perspectives on the management of diabetic peripheral neuropathic pain. Diab Vasc Dis Res 2006;3:108-19. (Pubitemid 44638385)
2. Schmader KE. Epidemiology and impact on quality of life of postherpetic neuralgia and painful diabetic neuropathy. Clin J Pain 2002;18:350-4. (Pubitemid 35291575)
3. Sator-Katzenschlager SM, Schiesser AW, Kozek-Langenecker SA, Benetka G, Langer G, Kress HG. Does pain relief improve pain behavior and mood in chronic pain patients? Anesth Analg 2003;97:791-7.
4. Veves A, Backonja M, Malik RA. Painful diabetic neuropathy: epidemiology, natural history, early diagnosis, and treatment options. Pain Med 2008;9: 660-74.
5. Christoph T, Kogel B, Strassburger W, Schug SA. Tramadol has a better potency ratio relative to morphine in neuropathic than in nociceptive pain models. Drugs R D 2007;8:51-7. (Pubitemid 46191807)
6. De Decker K, Cordonnier J, Jacobs W, Coucke V, Schepens P, Jorens PG. Fatal intoxication due to tramadol alone: case report and review of the literature. Forensic Sci Int 2008;175:79-82. (Pubitemid 351172649)
7. Vivancos Jr GG, Verri WA, Cunha TM, Schivo IR, Parada CA, Cunha FQ, et al. An electronic pressure-meter nociception paw test for rats. Braz J Med Biol Res 2004;37:391-9. (Pubitemid 38444530)
8. Rees DA, Alcolado JC. Animal models of diabetes mellitus. Diabet Med 2005;22:359-70. (Pubitemid 40516231)
9. Morrow TJ. Animal models of painful diabetic neuropathy: the STZ rat model. Curr Protoc Neurosci; 2004 [Chapter 9]: Unit 9.18.
10. Kamei J, Zushida K, Morita K, Sasaki M, Tanaka S. Role of vanilloid VR1 receptor in thermal allodynia and hyperalgesia in diabetic mice. Eur J Pharmacol 2001;422:83-6. (Pubitemid 32595578)
11. Davidson E, Coppey L, Lu B, Arballo V, Calcutt NA, Gerard C, et al. The roles of streptozotocin neurotoxicity and neutral endopeptidase in murine experimental diabetic neuropathy. Exp Diabetes Res 2009;2009:431980.
12. Tolle T, Xu X, Sadosky AB. Painful diabetic neuropathy: a cross-sectional survey of health state impairment and treatment patterns. J Diabetes Complications 2006;20:26-33. (Pubitemid 43028410)
13. Fox A, Eastwood C, Gentry C, Manning D, Urban L. Critical evaluation of the streptozotocin model of painful diabetic neuropathy in the rat. Pain 1999;81: 307-16. (Pubitemid 29257901)
14. Malcangio M, Tomlinson DR. A pharmacologic analysis of mechanical hyperalgesia in streptozotocin/diabetic rats. Pain 1998;76:151-7. (Pubitemid 28304951)
15. Kamiya H, Murakawa Y, Zhang W, Sima AA. Unmyelinated fiber sensory neuropathy differs in type 1 and type 2 diabetes. Diabetes Metab Res Rev 2005;21:448-58. (Pubitemid 41320656)
16. Freshwater JD, Svensson CI, Malmberg AB, Calcutt NA. Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes 2002;51:2249-55. (Pubitemid 34729032)
17. Courteix C, Bardin M, Massol J, Fialip J, Lavarenne J, Eschalier A. Daily insulin treatment relieves long-term hyperalgesia in streptozocin diabetic rats. Neuroreport 1996;7:1922-4. (Pubitemid 26348193)
18. Gardoni F, Kamal A, Bellone C, Biessels GJ, Ramakers GM, Cattabeni F, et al. Effects of streptozotocin-diabetes on the hippocampal NMDA receptor complex in rats. J Neurochem 2002;80:438-47. (Pubitemid 36383027)
19. Sounvoravong S, Nakashima MN, Wada M, Nakashima K. Decrease in serotonin concentration in raphe magnus nucleus and attenuation of morphine analgesia in two mice models of neuropathic pain. Eur J Pharmacol 2004;484:217-23. (Pubitemid 38117213)
20. Anjaneyulu M, Chopra K. Fluoxetine attenuates thermal hyperalgesia through 5-HT1/2 receptors in streptozotocin-induced diabetic mice. Eur J Pharmacol 2004;497:285-92. (Pubitemid 39164893)
21. Kuhad A, Bishnoi M, Chopra K. Anti-nociceptive effect of duloxetine in mouse model of diabetic neuropathic pain. Indian J Exp Biol 2009;47:193-7.
22. Harati Y, Gooch C, Swenson M, Edelman S, Greene D, Raskin P, et al. Doubleblind randomized trial of tramadol for the treatment of the pain of diabetic neuropathy. Neurology 1998;50:1842-6. (Pubitemid 28283262)
23. Alloui A, Chassaing C, Schmidt J, Ardid D, Dubray C, Cloarec A, et al. Paracetamol exerts a spinal, tropisetron-reversible, antinociceptive effect in an inflammatory pain model in rats. Eur J Pharmacol 2002;443:71-7. (Pubitemid 34603599)
24. Pelissier T, Alloui A, Caussade F, Dubray C, Cloarec A, Lavarenne J, et al. Paracetamol exerts a spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine3 receptors: in vivo and in vitro evidence. J Pharmacol Exp Ther 1996;278:8-14. (Pubitemid 27167073)
25. Hama AT, Sagen J. Cannabinoid receptor-mediated antinociception with acetaminophen drug combinations in rats with neuropathic spinal cord injury pain. Neuropharmacology 2010;58:758-66.
26. Filitz J, Ihmsen H, Gunther W, Troster A, Schwilden H, Schuttler J, et al. Supraadditive effects of tramadol and acetaminophen in a human pain model. Pain 2008;136:262-70. (Pubitemid 351680244)
27. Rosenthal NR, Silverfield JC, Wu SC, Jordan D, Kamin M. Tramadol/acetaminophen combination tablets for the treatment of pain associated with osteoarthritis flare in an elderly patient population. J Am Geriatr Soc 2004;52:374-80. (Pubitemid 38339517)
28. Smith AB, Ravikumar TS, Kamin M, Jordan D, Xiang J, Rosenthal N. Combination tramadol plus acetaminophen for postsurgical pain. Am J Surg 2004;187: 521-7. (Pubitemid 38373810)
29. Fricke Jr JR, Karim R, Jordan D, Rosenthal N. A double-blind, single-dose comparison of the analgesic efficacy of tramadol/acetaminophen combination tablets, hydrocodone/acetaminophen combination tablets, and placebo after oral surgery. Clin Ther 2002;24:953-68. (Pubitemid 34734741)
30. Tallarida RJ. Drug synergism and dose-effect data analysis. Boca Raton (FL): Chapman & Hall/CRC Press; 2000.