메뉴 건너뛰기




Volumn 15, Issue 5, 2009, Pages 537-552

Fibrates and microvascular complications in diabetes - Insight from the FIELD study

Author keywords

Diabetes; Fenofibrate; Fibrates; Nephropathy; Neuropathy; Retinopathy

Indexed keywords

ATROMID; BEZAFIBRATE; C REACTIVE PROTEIN; CLOFIBRATE; CREATININE; ETOFIBRATE; FENOFIBRATE; FIBRIC ACID DERIVATIVE; FIBRINOGEN; GEMFIBROZIL; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLACEBO; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; ANTILIPEMIC AGENT; CLOFIBRIC ACID;

EID: 64749088854     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161209787315701     Document Type: Review
Times cited : (83)

References (158)
  • 1
    • 33846262603 scopus 로고    scopus 로고
    • Fenofibrate: A review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus
    • Keating GM, Croom KF. Fenofibrate: A review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus. Drugs 2007; 67: 121-53.
    • (2007) Drugs , vol.67 , pp. 121-153
    • Keating, G.M.1    Croom, K.F.2
  • 2
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (The FIELD study): Randomised controlled trial
    • The FIELD Study Investigators
    • The FIELD Study Investigators. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (The FIELD study): Randomised controlled trial. Lancet 2005; 366: 1849-61.
    • (2005) Lancet , vol.366 , pp. 1849-1861
  • 3
    • 36049001784 scopus 로고    scopus 로고
    • Effect of fenofibrate on the ned for laser treatment for diabetic retinopathy (FIELD study): A randomised controlled trial
    • Keech AC, Mitchell P, Summanen PA, O'Day JO, Davis TME, Moffitt MS, et al. Effect of fenofibrate on the ned for laser treatment for diabetic retinopathy (FIELD study): A randomised controlled trial. Lancet 2007; 370: 1687-97.
    • (2007) Lancet , vol.370 , pp. 1687-1697
    • Keech, A.C.1    Mitchell, P.2    Summanen, P.A.3    O'Day, J.O.4    Davis, T.M.E.5    Moffitt, M.S.6
  • 4
    • 65649102450 scopus 로고    scopus 로고
    • Burgess D, Hunt D, Li L, Zhang J, Sy R, Laakso M, et al. Effects of fenofibrate on silent myocardial infarction, hospitalization for acute coronary syndromes and amputation in type 2 diabetes: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Circulation 2007; 116: II_838.
    • Burgess D, Hunt D, Li L, Zhang J, Sy R, Laakso M, et al. Effects of fenofibrate on silent myocardial infarction, hospitalization for acute coronary syndromes and amputation in type 2 diabetes: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Circulation 2007; 116: II_838.
  • 6
    • 33846564694 scopus 로고    scopus 로고
    • Robillard R, Fontaine C, Chinetti G, Fruchart JC, Staels B. Fibrates. Hand Exp Pharmacol 2005; 170: 389-406.
    • Robillard R, Fontaine C, Chinetti G, Fruchart JC, Staels B. Fibrates. Hand Exp Pharmacol 2005; 170: 389-406.
  • 7
    • 0025132245 scopus 로고
    • Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
    • Issemann I, Green S. Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators. Nature 1990, 347: 645-50.
    • (1990) Nature , vol.347 , pp. 645-650
    • Issemann, I.1    Green, S.2
  • 8
    • 0029791412 scopus 로고    scopus 로고
    • PPAR α and PPAR β activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
    • Schoonjans K, Peinado-Onsurbe J, Lefebvre AM, Heyman RA, Briggs M, Deeb S, et al. PPAR α and PPAR β activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J 1996; 15: 5336-48.
    • (1996) EMBO J , vol.15 , pp. 5336-5348
    • Schoonjans, K.1    Peinado-Onsurbe, J.2    Lefebvre, A.M.3    Heyman, R.A.4    Briggs, M.5    Deeb, S.6
  • 9
    • 0030794057 scopus 로고    scopus 로고
    • Peroxisome proliferator- activated receptors, orphans with ligands and functions
    • Schoonjans K, Martin G, Staels B, Auwerx J. Peroxisome proliferator- activated receptors, orphans with ligands and functions. Curr Opin Lipidol 1997; 8: 159-66.
    • (1997) Curr Opin Lipidol , vol.8 , pp. 159-166
    • Schoonjans, K.1    Martin, G.2    Staels, B.3    Auwerx, J.4
  • 10
    • 0038043229 scopus 로고    scopus 로고
    • Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator- activated receptor... activators
    • Vu-Dac N, Gervois P, Jakel H. Apolipoprotein A5, a crucial determinant of plasma triglyceride levels, is highly responsive to peroxisome proliferator- activated receptor... activators. J Biol Chem 2003, 278: 17982-85.
    • (2003) J Biol Chem , vol.278 , pp. 17982-17985
    • Vu-Dac, N.1    Gervois, P.2    Jakel, H.3
  • 11
    • 0038491484 scopus 로고    scopus 로고
    • The human apolipoprotein AV gene is regulated by PPAR.. and contains a novel FXR response element
    • Prieur X, Coste H, Rodriguez JC. The human apolipoprotein AV gene is regulated by PPAR.. and contains a novel FXR response element. J Biol Chem 2003; 278: 25468-80.
    • (2003) J Biol Chem , vol.278 , pp. 25468-25480
    • Prieur, X.1    Coste, H.2    Rodriguez, J.C.3
  • 12
    • 0028817459 scopus 로고
    • Fibrates down-regulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase
    • Staels B, Vu-Dac N, Kosykh V, Saladin R, Fruchart JC, Dallongeville J, Auwerx J. Fibrates down-regulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. J Clin Invest 1995; 95: 705-12.
    • (1995) J Clin Invest , vol.95 , pp. 705-712
    • Staels, B.1    Vu-Dac, N.2    Kosykh, V.3    Saladin, R.4    Fruchart, J.C.5    Dallongeville, J.6    Auwerx, J.7
  • 13
    • 0028036723 scopus 로고
    • Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element
    • Vu-Dac N, Schoonjans K, Laine B, Fruchart JC, Auwerx J, Staels B. Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J Biol Chem 1994, 269: 31012-8.
    • (1994) J Biol Chem , vol.269 , pp. 31012-31018
    • Vu-Dac, N.1    Schoonjans, K.2    Laine, B.3    Fruchart, J.C.4    Auwerx, J.5    Staels, B.6
  • 14
    • 0029119082 scopus 로고
    • Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor
    • Vu-Dac N, Schoonjans K, Kosykh V, Dallongeville J, Fruchart JC, Staels B, et al. Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J Clin Invest 1995, 96: 741-50.
    • (1995) J Clin Invest , vol.96 , pp. 741-750
    • Vu-Dac, N.1    Schoonjans, K.2    Kosykh, V.3    Dallongeville, J.4    Fruchart, J.C.5    Staels, B.6
  • 15
    • 20044396568 scopus 로고    scopus 로고
    • Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation
    • Duez H, Lefebvre B, Poulain P, Torra IP, Percevault F, Luc G, et al. Regulation of human apoA-I by gemfibrozil and fenofibrate through selective peroxisome proliferator-activated receptor alpha modulation. Arterioscler Thromb Vasc Biol 2005; 25: 585-91.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 585-591
    • Duez, H.1    Lefebvre, B.2    Poulain, P.3    Torra, I.P.4    Percevault, F.5    Luc, G.6
  • 16
    • 11844296800 scopus 로고    scopus 로고
    • Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds. A meta-analysis of randomized controlled trials
    • Birjmohun RS, Hutten BA, Kastelein JJP, Stroes ESG. Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds. A meta-analysis of randomized controlled trials. J Am Coll Cardiol 2005; 45: 185-97.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 185-197
    • Birjmohun, R.S.1    Hutten, B.A.2    Kastelein, J.J.P.3    Stroes, E.S.G.4
  • 18
    • 0023232216 scopus 로고
    • Helsinki Heart Study: Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia: Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N
    • Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, et al. Helsinki Heart Study: Primary prevention trial with gemfibrozil in middle-aged men with dyslipidemia: Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N Engl J Med 1987; 317: 1237-45.
    • (1987) Engl J Med , vol.317 , pp. 1237-1245
    • Frick, M.H.1    Elo, O.2    Haapa, K.3    Heinonen, O.P.4    Heinsalmi, P.5    Helo, P.6
  • 19
    • 0031922041 scopus 로고    scopus 로고
    • Cardiovascular outcomes in type 2 diabetes: A double-blind placebo-controlled study of bezafibrate: The St. Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study
    • Elkeles RS, Diamond JR, Poulter C, Dhanjil S, Mahmood S, Richmond W, et al. Cardiovascular outcomes in type 2 diabetes: A double-blind placebo-controlled study of bezafibrate: The St. Mary's, Ealing, Northwick Park Diabetes Cardiovascular Disease Prevention (SENDCAP) Study. Diabetes Care 1998; 21: 641-8.
    • (1998) Diabetes Care , vol.21 , pp. 641-648
    • Elkeles, R.S.1    Diamond, J.R.2    Poulter, C.3    Dhanjil, S.4    Mahmood, S.5    Richmond, W.6
  • 20
    • 0034604225 scopus 로고    scopus 로고
    • Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: The Bezafibrate Infarction Prevention (BIP) study
    • The BIP Study Group
    • The BIP Study Group. Secondary prevention by raising HDL cholesterol and reducing triglycerides in patients with coronary artery disease: The Bezafibrate Infarction Prevention (BIP) study. Circulation 2000; 102: 21-7.
    • (2000) Circulation , vol.102 , pp. 21-27
  • 21
    • 0036093659 scopus 로고    scopus 로고
    • Effects of micronized fenofibrate versus atorvastatin in the treatment of dyslipidaemic patients with low plasma HDL-cholesterol levels: A 12- week randomized trial
    • Despres J-P, Lemieux I, Salomon H, Delaval D. Effects of micronized fenofibrate versus atorvastatin in the treatment of dyslipidaemic patients with low plasma HDL-cholesterol levels: A 12- week randomized trial. J Intern Med 2002; 251: 490-9.
    • (2002) J Intern Med , vol.251 , pp. 490-499
    • Despres, J.-P.1    Lemieux, I.2    Salomon, H.3    Delaval, D.4
  • 22
    • 0029941224 scopus 로고    scopus 로고
    • Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalises the atherogenic, dense LDL profile in combined hyperlipidemia
    • Guerin M, Bruckert E, Dolphin PJ, Turpin G, Chapman MJ. Fenofibrate reduces plasma cholesteryl ester transfer from HDL to VLDL and normalises the atherogenic, dense LDL profile in combined hyperlipidemia. Arterioscler Thromb Vasc Biol 1996; 16: 763-72.
    • (1996) Arterioscler Thromb Vasc Biol , vol.16 , pp. 763-772
    • Guerin, M.1    Bruckert, E.2    Dolphin, P.J.3    Turpin, G.4    Chapman, M.J.5
  • 24
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol: Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group
    • Rubins HB, Robins SJ, Collins D, Fye CL, Anderson JW, Elam MB, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol: Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. N Engl J Med 1999; 341: 410-8.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3    Fye, C.L.4    Anderson, J.W.5    Elam, M.B.6
  • 25
    • 0037049366 scopus 로고    scopus 로고
    • Diabetes, plasma insulin and cardiovascular disease. Subgroup analysis from the Department of Veterans Affairs highdensity lipoprotein intervention trial (VA-HIT)
    • Rubins HB, Robins SJ, Collins D, Nelson DB, Elam MB, Schaefer EJ, et al. Diabetes, plasma insulin and cardiovascular disease. Subgroup analysis from the Department of Veterans Affairs highdensity lipoprotein intervention trial (VA-HIT). Arch Intern Med 2002; 162: 2597-604.
    • (2002) Arch Intern Med , vol.162 , pp. 2597-2604
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3    Nelson, D.B.4    Elam, M.B.5    Schaefer, E.J.6
  • 26
    • 0037121346 scopus 로고    scopus 로고
    • Bezafibrate in men with lower extremity arterial disease: Randomised controlled trial
    • Meade T, Zuhrie R, Cook C, Cooper J. Bezafibrate in men with lower extremity arterial disease: Randomised controlled trial. BMJ 2002; 325: 1139.
    • (2002) BMJ , vol.325 , pp. 1139
    • Meade, T.1    Zuhrie, R.2    Cook, C.3    Cooper, J.4
  • 27
    • 0029845294 scopus 로고    scopus 로고
    • Secondary preventive potential of lipid-lowering drugs: The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT)
    • de Faire U, Ericsson CG, Grip L, Nilsson J, Svane B, Hamsten A. Secondary preventive potential of lipid-lowering drugs: The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT). Eur Heart J 1996; 17: 37-42.
    • (1996) Eur Heart J , vol.17 , pp. 37-42
    • de Faire, U.1    Ericsson, C.G.2    Grip, L.3    Nilsson, J.4    Svane, B.5    Hamsten, A.6
  • 28
    • 0342506477 scopus 로고    scopus 로고
    • Lopid Coronary Angiography Trial (LOCAT) Study Group. Prevention of the angiographic progression of coronary and vein-graft therosclerosis by gemfibrozil after coronary bypass surgery in men with low evels of HDL cholesterol
    • Frick MH, Syvänne M, Nieminen MS, Kauma H, Majahalme S, Virtanen V, et al. Lopid Coronary Angiography Trial (LOCAT) Study Group. Prevention of the angiographic progression of coronary and vein-graft therosclerosis by gemfibrozil after coronary bypass surgery in men with low evels of HDL cholesterol. Circulation 1997; 96: 2137-43.
    • (1997) Circulation , vol.96 , pp. 2137-2143
    • Frick, M.H.1    Syvänne, M.2    Nieminen, M.S.3    Kauma, H.4    Majahalme, S.5    Virtanen, V.6
  • 29
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary- artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study
    • DAIS Investigators
    • DAIS Investigators. Effect of fenofibrate on progression of coronary- artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet 2001; 357: 905-10.
    • (2001) Lancet , vol.357 , pp. 905-910
  • 30
    • 0034782457 scopus 로고    scopus 로고
    • Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (fenofibrate versus atorvastatin trial - FAT)
    • Malik J, Melenovsky V, Wichterle D, Haas T, Simek J, Ceska R, Hradec J. Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (fenofibrate versus atorvastatin trial - FAT). Cardiovasc Res 2001; 52: 290-8.
    • (2001) Cardiovasc Res , vol.52 , pp. 290-298
    • Malik, J.1    Melenovsky, V.2    Wichterle, D.3    Haas, T.4    Simek, J.5    Ceska, R.6    Hradec, J.7
  • 31
    • 49649117315 scopus 로고    scopus 로고
    • Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction
    • Epub ahead of print
    • Chew GT, Watts GF, Davis TM, Stuckey BG, Beilin LJ, Thompson PL, et al. Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction. Diabetes Care 2008; 16. Epub ahead of print
    • (2008) Diabetes Care , pp. 16
    • Chew, G.T.1    Watts, G.F.2    Davis, T.M.3    Stuckey, B.G.4    Beilin, L.J.5    Thompson, P.L.6
  • 32
    • 0036094913 scopus 로고    scopus 로고
    • Pleiotropic actions of peroxisome proliferator- activated receptors in lipid metabolism and atherosclerosis. Arterioscler
    • Barbier O, Pineda Torra I, Dugay Y, Blanquart C, Fruchart JC, Glineur C, Staels B. Pleiotropic actions of peroxisome proliferator- activated receptors in lipid metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol 2002; 22: 717-26.
    • (2002) Thromb Vasc Biol , vol.22 , pp. 717-726
    • Barbier, O.1    Pineda Torra, I.2    Dugay, Y.3    Blanquart, C.4    Fruchart, J.C.5    Glineur, C.6    Staels, B.7
  • 35
    • 33644652183 scopus 로고    scopus 로고
    • Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis
    • Lefebvre P, Chinetti G, Fruchart JC, Staels B. Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis J Clin Invest 2006; 116: 571-80.
    • (2006) J Clin Invest , vol.116 , pp. 571-580
    • Lefebvre, P.1    Chinetti, G.2    Fruchart, J.C.3    Staels, B.4
  • 36
    • 33747253447 scopus 로고    scopus 로고
    • Aspirin and PPAR-alpha activators inhibit monocyte chemoattractant protein-1 expression induced high glucose concentration in human endothelial cells
    • Dragomir E, Tircol M, Manduteanu I, Voinea M, Simionescu M. Aspirin and PPAR-alpha activators inhibit monocyte chemoattractant protein-1 expression induced high glucose concentration in human endothelial cells. Vascul Pharmacol 2006; 44: 440-9.
    • (2006) Vascul Pharmacol , vol.44 , pp. 440-449
    • Dragomir, E.1    Tircol, M.2    Manduteanu, I.3    Voinea, M.4    Simionescu, M.5
  • 37
    • 33646393509 scopus 로고    scopus 로고
    • Effects of short-term fenofibrate treatment on circulating markers of inflammation and hemostasis in patients with impaired glucose tolerance
    • Okopień B, Krysiak R, Herman ZS. Effects of short-term fenofibrate treatment on circulating markers of inflammation and hemostasis in patients with impaired glucose tolerance. J Clin Endocrinol Metab 2006; 91: 1770-8.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 1770-1778
    • Okopień, B.1    Krysiak, R.2    Herman, Z.S.3
  • 38
    • 0344874601 scopus 로고    scopus 로고
    • Chapman MJ. Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives. Atherosclerosis 2003; 171: 1-13.
    • Chapman MJ. Fibrates in 2003: Therapeutic action in atherogenic dyslipidaemia and future perspectives. Atherosclerosis 2003; 171: 1-13.
  • 39
    • 33745685394 scopus 로고    scopus 로고
    • The reduction of inflammatory biomarkers by statin, fibrate, and combination therapy among diabetic patients with mixed dyslipidemia: The DIACOR (Diabetes and Combined Lipid Therapy Regimen) study
    • Muhlestein JB, May HT, Jensen JR, Horne BD, Lanman RB, Lavasani F, et al. The reduction of inflammatory biomarkers by statin, fibrate, and combination therapy among diabetic patients with mixed dyslipidemia: The DIACOR (Diabetes and Combined Lipid Therapy Regimen) study. J Am Coll Cardiol 2006; 48: 396-401.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 396-401
    • Muhlestein, J.B.1    May, H.T.2    Jensen, J.R.3    Horne, B.D.4    Lanman, R.B.5    Lavasani, F.6
  • 40
    • 0041641604 scopus 로고    scopus 로고
    • Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-containing lipoproteins
    • Tsimihodimos V, Kakafika A, Tambaki AP, Bairaktari E, Chapman MJ, Elisaf M, et al. Fenofibrate induces HDL-associated PAF-AH but attenuates enzyme activity associated with apoB-containing lipoproteins. J Lipid Res 2003; 44: 927-34.
    • (2003) J Lipid Res , vol.44 , pp. 927-934
    • Tsimihodimos, V.1    Kakafika, A.2    Tambaki, A.P.3    Bairaktari, E.4    Chapman, M.J.5    Elisaf, M.6
  • 42
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27: 1047-53.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 43
    • 65649105980 scopus 로고    scopus 로고
    • CDC National Health Interview Survey (NHIS) Early Release of Selected Estimates Based on Data From the January-September 2007 National Health Interview Survey
    • CDC National Health Interview Survey (NHIS) Early Release of Selected Estimates Based on Data From the January-September 2007 National Health Interview Survey
  • 44
    • 24144472565 scopus 로고    scopus 로고
    • The burden of mortality attributable to diabetes: Realistic estimates for the year 2000
    • Roglic G, Unwin N, Bennett PH, Mathers C, Tuomilehto J, Nag S, et al. The burden of mortality attributable to diabetes: Realistic estimates for the year 2000. Diabetes Care 2005; 28: 2130-5.
    • (2005) Diabetes Care , vol.28 , pp. 2130-2135
    • Roglic, G.1    Unwin, N.2    Bennett, P.H.3    Mathers, C.4    Tuomilehto, J.5    Nag, S.6
  • 45
    • 42349087252 scopus 로고    scopus 로고
    • Microvascular and Macrovascular Complications of Diabetes
    • Fowler MJ. Microvascular and Macrovascular Complications of Diabetes. Clinical Diabetes 2008; 26: 77-82.
    • (2008) Clinical Diabetes , vol.26 , pp. 77-82
    • Fowler, M.J.1
  • 46
    • 34247606478 scopus 로고    scopus 로고
    • Incidence of coronary heart disease in type 2 diabetic men and women: Impact of microvascular complications, treatment, and geographic location
    • Avogaro A, Giorda C, Maggini M, Mannucci E, Raschetti R, Lombardo F, et al. Incidence of coronary heart disease in type 2 diabetic men and women: Impact of microvascular complications, treatment, and geographic location. Diabetes Care 2007; 30: 1241-7.
    • (2007) Diabetes Care , vol.30 , pp. 1241-1247
    • Avogaro, A.1    Giorda, C.2    Maggini, M.3    Mannucci, E.4    Raschetti, R.5    Lombardo, F.6
  • 47
    • 34447135411 scopus 로고    scopus 로고
    • Diabetic retinopathy and the risk of coronary heart disease. The Atherosclerosis Risk in Communities Study
    • Cheung N, Wang JJ, Klein R, Couper DJ, Sharrett AR, Wong TY. Diabetic retinopathy and the risk of coronary heart disease. The Atherosclerosis Risk in Communities Study. Diabetes Care 2007a; 30: 1742-6.
    • (2007) Diabetes Care , vol.30 , pp. 1742-1746
    • Cheung, N.1    Wang, J.J.2    Klein, R.3    Couper, D.J.4    Sharrett, A.R.5    Wong, T.Y.6
  • 48
    • 33846626856 scopus 로고    scopus 로고
    • Is diabetic retinopathy an independent risk factor for ischemic stroke?
    • Cheung N, Rogers S, Couper DJ. Is diabetic retinopathy an independent risk factor for ischemic stroke? Stroke 2007; 38: 398-401.
    • (2007) Stroke , vol.38 , pp. 398-401
    • Cheung, N.1    Rogers, S.2    Couper, D.J.3
  • 49
    • 38049139343 scopus 로고    scopus 로고
    • Diabetic retinopathy is associated with an increased incidence of cardiovascular events in type 2 diabetic patients
    • Targher G, Bertolini L, Zenari L, Lippi G, Pichiri I, Zoppini G, et al. Diabetic retinopathy is associated with an increased incidence of cardiovascular events in type 2 diabetic patients. Diabetes Med 2008; 25: 45-50.
    • (2008) Diabetes Med , vol.25 , pp. 45-50
    • Targher, G.1    Bertolini, L.2    Zenari, L.3    Lippi, G.4    Pichiri, I.5    Zoppini, G.6
  • 51
    • 33846686823 scopus 로고    scopus 로고
    • Retinopathy predicts cardiovascular mortality in type 2 diabetic men and women
    • Juutilainen A, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Retinopathy predicts cardiovascular mortality in type 2 diabetic men and women. Diabetes Care 2007; 30: 292-9.
    • (2007) Diabetes Care , vol.30 , pp. 292-299
    • Juutilainen, A.1    Lehto, S.2    Rönnemaa, T.3    Pyörälä, K.4    Laakso, M.5
  • 52
    • 65649113769 scopus 로고    scopus 로고
    • Prevention of blindness from Diabetes Mellitus. Report of a WHO consultation in Geneva, 9-11 November 2005. WHO Library Cataloguin- in-publication Data
    • Prevention of blindness from Diabetes Mellitus. Report of a WHO consultation in Geneva, 9-11 November 2005. WHO Library Cataloguin- in-publication Data
  • 55
    • 35348940263 scopus 로고    scopus 로고
    • Etiology and natural history of diabetic retinopathy: An overview
    • Morello CM. Etiology and natural history of diabetic retinopathy: An overview. Am J Health Syst Pharm 2007; 64: S3-7.
    • (2007) Am J Health Syst Pharm , vol.64
    • Morello, C.M.1
  • 57
    • 35548941085 scopus 로고    scopus 로고
    • Diabetic retinopathy: Treatment and prevention
    • Dodson P. Diabetic retinopathy: Treatment and prevention. Diabetes Vasc Dis Res 2007; 4: S9-S11.
    • (2007) Diabetes Vasc Dis Res , vol.4
    • Dodson, P.1
  • 59
    • 0037213037 scopus 로고    scopus 로고
    • Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA, Holman RR; UKPDS GROUP. Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney Int 2003; 63: 225-32.
    • Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA, Holman RR; UKPDS GROUP. Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64). Kidney Int 2003; 63: 225-32.
  • 60
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993; 329: 977-86.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 61
    • 43849108986 scopus 로고    scopus 로고
    • Mild renal impairment and cardiovascular outcomes in type 2 diabetes: Results from the FIELD study
    • Drury P on behalf of the FIELD Study Investigators
    • Drury P on behalf of the FIELD Study Investigators. Mild renal impairment and cardiovascular outcomes in type 2 diabetes: Results from the FIELD study. Diabetologia 2006; 49(Suppl 1): 6-7.
    • (2006) Diabetologia , vol.49 , Issue.SUPPL. 1 , pp. 6-7
  • 62
    • 22844439519 scopus 로고    scopus 로고
    • Associations between retinal microvascular abnormalities and declining renal function in the elderly population: The Cardiovascular Health Study
    • Edwards MS, Wilson DB, Craven TE, Stafford J, Fried LF, Wong TY, et al. Associations between retinal microvascular abnormalities and declining renal function in the elderly population: The Cardiovascular Health Study. Am J Kidney Dis 2005; 46: 214-24.
    • (2005) Am J Kidney Dis , vol.46 , pp. 214-224
    • Edwards, M.S.1    Wilson, D.B.2    Craven, T.E.3    Stafford, J.4    Fried, L.F.5    Wong, T.Y.6
  • 63
    • 0033401063 scopus 로고    scopus 로고
    • The epidemiology of diabetic neuropathy
    • Shaw JE, Zimmet PZ. The epidemiology of diabetic neuropathy. Diabetes Rev 1999; 7: 245-52.
    • (1999) Diabetes Rev , vol.7 , pp. 245-252
    • Shaw, J.E.1    Zimmet, P.Z.2
  • 64
    • 30544436116 scopus 로고    scopus 로고
    • Prevalence of polyneuropathy in impaired glucose tolerance and diabetes. The MONICA/KORA Augsburg Surveys and Myocardial Infarction Registry (KORA-A Study)
    • Ziegler D, Rathmann W, Haastert B, Füchsle-Reiter A, Löwel H, Mielck A. Prevalence of polyneuropathy in impaired glucose tolerance and diabetes. The MONICA/KORA Augsburg Surveys and Myocardial Infarction Registry (KORA-A Study). Diabetologia 2005; 48: A364-5.
    • (2005) Diabetologia , vol.48
    • Ziegler, D.1    Rathmann, W.2    Haastert, B.3    Füchsle-Reiter, A.4    Löwel, H.5    Mielck, A.6
  • 68
    • 0029785455 scopus 로고    scopus 로고
    • The absence of glycemic threshold for the development of long-term complications: The perspective of the Diabetes Control and Complications Trial
    • The Diabetes Control and Complication Trial Research Group
    • The Diabetes Control and Complication Trial Research Group. The absence of glycemic threshold for the development of long-term complications: the perspective of the Diabetes Control and Complications Trial. Diabetes 1996; 45: 1289-98.
    • (1996) Diabetes , vol.45 , pp. 1289-1298
  • 69
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352: 837-53.
    • (1998) Lancet , vol.352 , pp. 837-853
  • 70
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study (UKPDS) Group
    • UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998; 352: 854-65.
    • (1998) Lancet , vol.352 , pp. 854-865
  • 71
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. BMJ 1998; 317: 703-13.
    • (1998) BMJ , vol.317 , pp. 703-713
  • 72
    • 45149131667 scopus 로고    scopus 로고
    • Effects of intensive glucose lowering in type 2 diabetes. N
    • The Action to Control Cardiovascular Risk in Diabetes Study Group
    • The Action to Control Cardiovascular Risk in Diabetes Study Group. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008; 358: 2545-59.
    • (2008) Engl J Med , vol.358 , pp. 2545-2559
  • 73
    • 45149133036 scopus 로고    scopus 로고
    • Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes
    • The ADVANCE Collaborative Group
    • The ADVANCE Collaborative Group. Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med 2008; 358: 2560-72.
    • (2008) N Engl J Med , vol.358 , pp. 2560-2572
  • 74
    • 34250694874 scopus 로고    scopus 로고
    • Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORDEYE)
    • Chew EY, Ambrosius WT, Howard LT, Greven CM, Johnson S, Danis RP, et al. Rationale, design, and methods of the Action to Control Cardiovascular Risk in Diabetes Eye Study (ACCORDEYE). Am J Cardiol 2007; 99: [suppl]103i-111i.
    • (2007) Am J Cardiol , vol.99 , Issue.SUPPL.
    • Chew, E.Y.1    Ambrosius, W.T.2    Howard, L.T.3    Greven, C.M.4    Johnson, S.5    Danis, R.P.6
  • 75
    • 8144221037 scopus 로고    scopus 로고
    • UK Prospective Diabetes Study Group. Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus: UKPDS 69
    • Matthews DR, Stratton IM, Aldington SJ, Holman RR, Kohner EM; UK Prospective Diabetes Study Group. Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus: UKPDS 69. Arch Ophthalmol 2004; 122: 1631-40.
    • (2004) Arch Ophthalmol , vol.122 , pp. 1631-1640
    • Matthews, D.R.1    Stratton, I.M.2    Aldington, S.J.3    Holman, R.R.4    Kohner, E.M.5
  • 76
    • 0036190137 scopus 로고    scopus 로고
    • Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes
    • Schrier RW, Estacio RO, Esler A, Mehler P. Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes. Kidney Int 2002; 61: 1086-97.
    • (2002) Kidney Int , vol.61 , pp. 1086-1097
    • Schrier, R.W.1    Estacio, R.O.2    Esler, A.3    Mehler, P.4
  • 77
    • 39449122983 scopus 로고    scopus 로고
    • A longitudinal study of risk factors for incident albuminuria in diabetic American Indians: The Strong Heart Study
    • Xu J, Lee ET, Devereux RB, Umans JG, Bella JN, Shara NM, et al. A longitudinal study of risk factors for incident albuminuria in diabetic American Indians: The Strong Heart Study. Am J Kidney Dis 2008; 51: 415-24.
    • (2008) Am J Kidney Dis , vol.51 , pp. 415-424
    • Xu, J.1    Lee, E.T.2    Devereux, R.B.3    Umans, J.G.4    Bella, J.N.5    Shara, N.M.6
  • 79
    • 37549072191 scopus 로고    scopus 로고
    • Circulating cholesterol as a modulator of risk for renal injury in patients with type 2 diabetes
    • Earle KA, Harry D, Zitouni K. Circulating cholesterol as a modulator of risk for renal injury in patients with type 2 diabetes. Diabetes Res Clin Pract 2008; 79: 68-73.
    • (2008) Diabetes Res Clin Pract , vol.79 , pp. 68-73
    • Earle, K.A.1    Harry, D.2    Zitouni, K.3
  • 80
    • 41949135184 scopus 로고    scopus 로고
    • Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: The Hoorn Study
    • Van Hecke MV, Dekker JM, Nijpels G, Teerlink T, Jakobs C, Stolk RP, et al. Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: The Hoorn Study. Clin Sci (Lond) 2008; 114: 479-87.
    • (2008) Clin Sci (Lond) , vol.114 , pp. 479-487
    • Van Hecke, M.V.1    Dekker, J.M.2    Nijpels, G.3    Teerlink, T.4    Jakobs, C.5    Stolk, R.P.6
  • 81
    • 30744468605 scopus 로고    scopus 로고
    • Increased serum levels of the specific advanced glycation end product methylglyoxal-derived hydroimidazolone are associated with retinopathy in patients with type 2 diabetes mellitus
    • Fosmark DA, Torjesen PA, Kilhovd BK, Berg TJ, Sandvik L, Hanssen KF, et al. Increased serum levels of the specific advanced glycation end product methylglyoxal-derived hydroimidazolone are associated with retinopathy in patients with type 2 diabetes mellitus. Metabolism 2006; 55: 232-6.
    • (2006) Metabolism , vol.55 , pp. 232-236
    • Fosmark, D.A.1    Torjesen, P.A.2    Kilhovd, B.K.3    Berg, T.J.4    Sandvik, L.5    Hanssen, K.F.6
  • 82
    • 33845499518 scopus 로고    scopus 로고
    • The metabolic syndrome is a risk indicator of microvascular and macrovascular complications in diabetes
    • The Metascreen Writing Committee
    • The Metascreen Writing Committee. The metabolic syndrome is a risk indicator of microvascular and macrovascular complications in diabetes. Diabetes Care 2006; 29: 2701-7.
    • (2006) Diabetes Care , vol.29 , pp. 2701-2707
  • 83
    • 2442447371 scopus 로고    scopus 로고
    • Danish Study Group of Diabetes in Childhood. The significance of the prepubertal diabetes duration for the development of retinopathy and nephropathy in patients with type 1 diabetes
    • Olsen BS, Sjølie AK, Hougaard P, Johannesen J, Marinelli K, Jacobsen BB, Mortensen HB; Danish Study Group of Diabetes in Childhood. The significance of the prepubertal diabetes duration for the development of retinopathy and nephropathy in patients with type 1 diabetes. J Diabetes Complicat 2004; 18: 160-4.
    • (2004) J Diabetes Complicat , vol.18 , pp. 160-164
    • Olsen, B.S.1    Sjølie, A.K.2    Hougaard, P.3    Johannesen, J.4    Marinelli, K.5    Jacobsen, B.B.6    Mortensen, H.B.7
  • 84
    • 36849078895 scopus 로고    scopus 로고
    • Familial risk factors for microvascular complications and differential male-female risk in a large cohort of american families with Type 1 diabetes
    • Monti MC, Lonsdale JT, Montomoli C, Montross R, Schlag E, Greenberg DA. Familial risk factors for microvascular complications and differential male-female risk in a large cohort of american families with Type 1 diabetes. J Clin Endocrinol Metab 2007; 92: 4650-5.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 4650-4655
    • Monti, M.C.1    Lonsdale, J.T.2    Montomoli, C.3    Montross, R.4    Schlag, E.5    Greenberg, D.A.6
  • 85
    • 0036713994 scopus 로고    scopus 로고
    • The role of genetic susceptibility in diabetic nephropathy: Evidence from family studies
    • Fava S, Hattersley AT. The role of genetic susceptibility in diabetic nephropathy: Evidence from family studies. Nephrol Dial Transplant 2002; 17: 1543-6.
    • (2002) Nephrol Dial Transplant , vol.17 , pp. 1543-1546
    • Fava, S.1    Hattersley, A.T.2
  • 86
    • 44349193611 scopus 로고    scopus 로고
    • Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications
    • Tong Z, Yang Z, Patel S, Chen H, Gibbs D, Yang X, et al. Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications. Proc Natl Acad Sci USA 2008; 105: 6998-7003.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6998-7003
    • Tong, Z.1    Yang, Z.2    Patel, S.3    Chen, H.4    Gibbs, D.5    Yang, X.6
  • 87
    • 0035668758 scopus 로고    scopus 로고
    • Risk factors for progression to proliferative diabetic retinopathy in the EURODIAB Prospective Complications Study
    • Porta M, Sjoelie AK, Chaturvedi N, Stevens L, Rottiers R, Veglio M, et al. Risk factors for progression to proliferative diabetic retinopathy in the EURODIAB Prospective Complications Study. Diabetologia 2001; 44: 2203-9.
    • (2001) Diabetologia , vol.44 , pp. 2203-2209
    • Porta, M.1    Sjoelie, A.K.2    Chaturvedi, N.3    Stevens, L.4    Rottiers, R.5    Veglio, M.6
  • 88
    • 0033799246 scopus 로고    scopus 로고
    • Effect of intensive glycemic control on micro-albuminuria in type 2 diabetes. Veterans Affairs Cooperative Study on Glycemic Control and Complications in Type 2 Diabetes Feasibility Trial Investigators
    • Levin SR, Coburn JW, Abraira C, Henderson WG, Colwell JA, Emanuele NV, et al. Effect of intensive glycemic control on micro-albuminuria in type 2 diabetes. Veterans Affairs Cooperative Study on Glycemic Control and Complications in Type 2 Diabetes Feasibility Trial Investigators. Diabetes Care 2000; 23: 1478-85.
    • (2000) Diabetes Care , vol.23 , pp. 1478-1485
    • Levin, S.R.1    Coburn, J.W.2    Abraira, C.3    Henderson, W.G.4    Colwell, J.A.5    Emanuele, N.V.6
  • 89
    • 0035790341 scopus 로고    scopus 로고
    • Risk factors for diabetic neuropathy and foot ulceration
    • Adler A. Risk factors for diabetic neuropathy and foot ulceration. Curr Diabetes Rep 2001; 1: 202-7.
    • (2001) Curr Diabetes Rep , vol.1 , pp. 202-207
    • Adler, A.1
  • 90
    • 33644792249 scopus 로고    scopus 로고
    • Development, progression, and regression of micro-albuminuria in Japanese patients with type 2 diabetes under tight glycemic and blood pressure control: The Kashiwa study
    • Yamada T, Komatsu M, Komiya I, Miyahara Y, Shima Y, Matsuzaki M, et al. Development, progression, and regression of micro-albuminuria in Japanese patients with type 2 diabetes under tight glycemic and blood pressure control: The Kashiwa study. Diabetes Care 2005; 28: 2733-8.
    • (2005) Diabetes Care , vol.28 , pp. 2733-2738
    • Yamada, T.1    Komatsu, M.2    Komiya, I.3    Miyahara, Y.4    Shima, Y.5    Matsuzaki, M.6
  • 92
    • 37349114574 scopus 로고    scopus 로고
    • Risk factors for development and progression of diabetic kidney disease and treatment patterns among diabetic siblings of patients with diabetic kidney disease
    • Bleyer AJ, Sedor JR, Freedman BI, O'Brien A, Russell GB, Graley J, Schelling JR. Risk factors for development and progression of diabetic kidney disease and treatment patterns among diabetic siblings of patients with diabetic kidney disease. Am J Kidney Dis 2008; 51: 29-37.
    • (2008) Am J Kidney Dis , vol.51 , pp. 29-37
    • Bleyer, A.J.1    Sedor, J.R.2    Freedman, B.I.3    O'Brien, A.4    Russell, G.B.5    Graley, J.6    Schelling, J.R.7
  • 93
    • 0037068623 scopus 로고    scopus 로고
    • Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes
    • Lurbe E, Redon J, Kesani A, Pascual JM, Tacons J, Alvarez V, Batlle D. Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes. N Engl J Med 2002; 347: 797-805.
    • (2002) N Engl J Med , vol.347 , pp. 797-805
    • Lurbe, E.1    Redon, J.2    Kesani, A.3    Pascual, J.M.4    Tacons, J.5    Alvarez, V.6    Batlle, D.7
  • 94
    • 33745626108 scopus 로고    scopus 로고
    • Increased prevalence of microvascular complications in type 2 diabetes patients with the metabolic syndrome
    • Abdul-Ghani M, Nawaf G, Nawaf F, Itzhak B, Minuchin O, Vardi P. Increased prevalence of microvascular complications in type 2 diabetes patients with the metabolic syndrome. Isr Med Assoc J 2006; 8: 378-82.
    • (2006) Isr Med Assoc J , vol.8 , pp. 378-382
    • Abdul-Ghani, M.1    Nawaf, G.2    Nawaf, F.3    Itzhak, B.4    Minuchin, O.5    Vardi, P.6
  • 96
    • 0036548892 scopus 로고    scopus 로고
    • Risk factors of developing proliferative retinopathy in type 1 diabetic patients: Role of BMI
    • Dorchy H, Claes C, Verougstraete C. Risk factors of developing proliferative retinopathy in type 1 diabetic patients: Role of BMI. Diabetes Care 2003; 25: 798-9.
    • (2003) Diabetes Care , vol.25 , pp. 798-799
    • Dorchy, H.1    Claes, C.2    Verougstraete, C.3
  • 97
    • 0029973124 scopus 로고    scopus 로고
    • Cigarette smoking and progression of retinopathy and nephropathy in type 1 diabetes
    • Muhlhauser I, Bender R, Bott U, Jorgens V, Grusser M, Wagener W, et al. Cigarette smoking and progression of retinopathy and nephropathy in type 1 diabetes. Diabetes Med 1996; 13: 536-43.
    • (1996) Diabetes Med , vol.13 , pp. 536-543
    • Muhlhauser, I.1    Bender, R.2    Bott, U.3    Jorgens, V.4    Grusser, M.5    Wagener, W.6
  • 98
    • 0037354252 scopus 로고    scopus 로고
    • Cigarette smoking and diabetes
    • Eliasson B. Cigarette smoking and diabetes. Prog Cardiovasc Dis 2003; 45: 405-13.
    • (2003) Prog Cardiovasc Dis , vol.45 , pp. 405-413
    • Eliasson, B.1
  • 99
    • 0037223891 scopus 로고    scopus 로고
    • Cigarette smoking and increased urine albumin excretion are interrelated predictors of nephropathy progression in type 2 diabetes
    • Chuahirun T, Khanna A, Kimball K, Wesson DE. Cigarette smoking and increased urine albumin excretion are interrelated predictors of nephropathy progression in type 2 diabetes. Am J Kidney Dis 2003; 41: 13-21.
    • (2003) Am J Kidney Dis , vol.41 , pp. 13-21
    • Chuahirun, T.1    Khanna, A.2    Kimball, K.3    Wesson, D.E.4
  • 101
    • 44449173148 scopus 로고    scopus 로고
    • Effect of LDL cholesterol and treatment with losartan on end-stage renal disease in the RENAAL study
    • Tershakovec AM, Keane WF, Zhang Z, Lyle PA, Appel GB, McGill JB, et al. Effect of LDL cholesterol and treatment with losartan on end-stage renal disease in the RENAAL study. Diabetes Care 2008; 31: 445-7.
    • (2008) Diabetes Care , vol.31 , pp. 445-447
    • Tershakovec, A.M.1    Keane, W.F.2    Zhang, Z.3    Lyle, P.A.4    Appel, G.B.5    McGill, J.B.6
  • 103
    • 0345249701 scopus 로고    scopus 로고
    • EURODIAB Prospective Complications Study Group. Circulating and urinary transforming growth factor beta1, Amadori albumin, and complications of type 1 diabetes: The EURODIAB prospective complications study
    • Chaturvedi N, Schalkwijk CG, Abrahamian H, Fuller JH, Stehouwer CD; EURODIAB Prospective Complications Study Group. Circulating and urinary transforming growth factor beta1, Amadori albumin, and complications of type 1 diabetes: The EURODIAB prospective complications study. Diabetes Care 2002; 25: 2320-7.
    • (2002) Diabetes Care , vol.25 , pp. 2320-2327
    • Chaturvedi, N.1    Schalkwijk, C.G.2    Abrahamian, H.3    Fuller, J.H.4    Stehouwer, C.D.5
  • 105
    • 0021136256 scopus 로고
    • The Wisconsin Epidemiologic Study of Diabetic Retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years
    • Klein R, Klein BE, Moss SE, Davis MD, DeMets DL. The Wisconsin Epidemiologic Study of Diabetic Retinopathy. II. Prevalence and risk of diabetic retinopathy when age at diagnosis is less than 30 years. Arch Ophthalmol 1984; 102: 520-6.
    • (1984) Arch Ophthalmol , vol.102 , pp. 520-526
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3    Davis, M.D.4    DeMets, D.L.5
  • 106
    • 34547691507 scopus 로고    scopus 로고
    • Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: The 50-year medalist study
    • Keenan HA, Costacou T, Sun JK, Doria A, Cavellerano J, Coney J, et al. Clinical factors associated with resistance to microvascular complications in diabetic patients of extreme disease duration: The 50-year medalist study. Diabetes Care 2007; 30: 1995-7.
    • (2007) Diabetes Care , vol.30 , pp. 1995-1997
    • Keenan, H.A.1    Costacou, T.2    Sun, J.K.3    Doria, A.4    Cavellerano, J.5    Coney, J.6
  • 107
    • 0034956879 scopus 로고    scopus 로고
    • Duration of non-insulin-dependent diabetes mellitus and the TNF-beta NcoI genotype as predictive factors in proliferative diabetic retinopathy
    • Kancaronkováa K, Muzcaroníka J, Karáskováb J, Beráneka M, Hájeka D, Znojila V, et al. Duration of non-insulin-dependent diabetes mellitus and the TNF-beta NcoI genotype as predictive factors in proliferative diabetic retinopathy. Ophthalmologica 2001; 215: 294-8.
    • (2001) Ophthalmologica , vol.215 , pp. 294-298
    • Kancaronkováa, K.1    Muzcaroníka, J.2    Karáskováb, J.3    Beráneka, M.4    Hájeka, D.5    Znojila, V.6
  • 108
    • 14644407375 scopus 로고    scopus 로고
    • Aldose reductase (AC)n gene polymorphism and susceptibility to diabetic retinopathy in Type 2 diabetes in Caucasians
    • Petrovič MG, Peterlin B, Hawlina M, Petrovič D. Aldose reductase (AC)n gene polymorphism and susceptibility to diabetic retinopathy in Type 2 diabetes in Caucasians. J diabetes Complicat 2005; 19: 70-3.
    • (2005) J diabetes Complicat , vol.19 , pp. 70-73
    • Petrovič, M.G.1    Peterlin, B.2    Hawlina, M.3    Petrovič, D.4
  • 109
    • 38949127276 scopus 로고    scopus 로고
    • MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients
    • Maeda M, Yamamoto I, Fukuda M, Motomura T, Nishida M, None S, et al. MTHFR gene polymorphism is susceptible to diabetic retinopathy but not to diabetic nephropathy in Japanese type 2 diabetic patients. J Diabetes Complicat 2008; 22: 119-25.
    • (2008) J Diabetes Complicat , vol.22 , pp. 119-125
    • Maeda, M.1    Yamamoto, I.2    Fukuda, M.3    Motomura, T.4    Nishida, M.5    None, S.6
  • 111
    • 23044433655 scopus 로고    scopus 로고
    • Ethnicity, race, and baseline retinopathy correlates in the Veterans Affairs Diabetes Trial
    • Emanuele N, Sacks J, Klein R, Reda D, Anderson R, Duckworth W, et al. Ethnicity, race, and baseline retinopathy correlates in the Veterans Affairs Diabetes Trial. Diabetes Care 2005; 28: 1954-8.
    • (2005) Diabetes Care , vol.28 , pp. 1954-1958
    • Emanuele, N.1    Sacks, J.2    Klein, R.3    Reda, D.4    Anderson, R.5    Duckworth, W.6
  • 113
    • 0029757496 scopus 로고    scopus 로고
    • Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. ETDRS
    • Chew EY, Klein ML, Ferris FL 3rd, Remaley NA, Murphy RP, Chantry K, et al. Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy. ETDRS Report 22. Arch Ophthalmol 1996; 114: 1079-84.
    • (1996) Arch Ophthalmol , vol.114 , pp. 1079-1084
    • Chew, E.Y.1    Klein, M.L.2    Ferris 3rd, F.L.3    Remaley, N.A.4    Murphy, R.P.5    Chantry, K.6
  • 114
    • 34249719349 scopus 로고    scopus 로고
    • The importance of serum lipids in exudative diabetic macular edema in type 2 diabetic patients
    • Ucgun NI, Yildirim Z, Kilic N, Gursel E. The importance of serum lipids in exudative diabetic macular edema in type 2 diabetic patients. Ann NY Acad Sci 2007; 100: 213-7.
    • (2007) Ann NY Acad Sci , vol.100 , pp. 213-217
    • Ucgun, N.I.1    Yildirim, Z.2    Kilic, N.3    Gursel, E.4
  • 115
    • 0036861529 scopus 로고    scopus 로고
    • The role of serum lipids in exudative diabetic maculopathy: Is there a place for lipid-lowering therapy?
    • Chowdhury TA, Hopkins D, Dodson PM, Vafidis GC. The role of serum lipids in exudative diabetic maculopathy: Is there a place for lipid-lowering therapy? Eye 2002; 16: 689-93.
    • (2002) Eye , vol.16 , pp. 689-693
    • Chowdhury, T.A.1    Hopkins, D.2    Dodson, P.M.3    Vafidis, G.C.4
  • 116
    • 0031917205 scopus 로고    scopus 로고
    • Risk factors for high-risk proliferative diabetic retinopathy and severe visual loss. Early Treatment Diabetic Retinopathy Study
    • Davis MD, Fisher MR, Gangnon RE, Barton F, Aiello LM, Chew EY, et al. Risk factors for high-risk proliferative diabetic retinopathy and severe visual loss. Early Treatment Diabetic Retinopathy Study Report 18. Invest Ophthalmol Vis Sci 1998; 39: 233-52.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 233-252
    • Davis, M.D.1    Fisher, M.R.2    Gangnon, R.E.3    Barton, F.4    Aiello, L.M.5    Chew, E.Y.6
  • 117
    • 0025285964 scopus 로고
    • Factors associated with avoidance of severe complications after 25 yr of IDDM. Pittsburgh Epidemiology of Diabetes Complications Study I
    • Orchard TJ, Dorman JS, Maser RE, Becker DJ, Ellis D, LaPorte RE, et al. Factors associated with avoidance of severe complications after 25 yr of IDDM. Pittsburgh Epidemiology of Diabetes Complications Study I. Diabetes Care 1990; 13: 741-7.
    • (1990) Diabetes Care , vol.13 , pp. 741-747
    • Orchard, T.J.1    Dorman, J.S.2    Maser, R.E.3    Becker, D.J.4    Ellis, D.5    LaPorte, R.E.6
  • 120
    • 0032707181 scopus 로고    scopus 로고
    • Association of plasma fibrinogen level and blood pressure with diabetic retinopathy, and renal complications associated with proliferative diabetic retinopathy, in Type 2 diabetes mellitus
    • Fujisawa T, Ikegami H, Yamato E, Kawaguchi Y, Ueda H, Shintani M, et al. Association of plasma fibrinogen level and blood pressure with diabetic retinopathy, and renal complications associated with proliferative diabetic retinopathy, in Type 2 diabetes mellitus. Diabetes Med 1999; 16: 522-6.
    • (1999) Diabetes Med , vol.16 , pp. 522-526
    • Fujisawa, T.1    Ikegami, H.2    Yamato, E.3    Kawaguchi, Y.4    Ueda, H.5    Shintani, M.6
  • 121
    • 33748309114 scopus 로고    scopus 로고
    • UKPDS Study Group. Risk factors for renal dysfunction in type 2 diabetes. UK Prospective Diabetes Study 74
    • Retnakaran R, Cull CA, Thorne KI, Adler AI, Holman RR; UKPDS Study Group. Risk factors for renal dysfunction in type 2 diabetes. UK Prospective Diabetes Study 74. Diabetes 2006; 55: 1832-9.
    • (2006) Diabetes , vol.55 , pp. 1832-1839
    • Retnakaran, R.1    Cull, C.A.2    Thorne, K.I.3    Adler, A.I.4    Holman, R.R.5
  • 122
    • 1842611390 scopus 로고    scopus 로고
    • Serum triglycerides are a predictive factor for the development and the progression of renal and retinal complications in patients with type 1 diabetes
    • Hadjadj S, Duly-Bouhanick B, Bekherraz A, Bridoux F, Gallois Y, Mauco G, et al. Serum triglycerides are a predictive factor for the development and the progression of renal and retinal complications in patients with type 1 diabetes. Diabetes Metab 2004; 30: 43-51.
    • (2004) Diabetes Metab , vol.30 , pp. 43-51
    • Hadjadj, S.1    Duly-Bouhanick, B.2    Bekherraz, A.3    Bridoux, F.4    Gallois, Y.5    Mauco, G.6
  • 123
    • 4344645765 scopus 로고    scopus 로고
    • Risk factors for renal replacement therapy in the Early Treatment Diabetic Retinopathy Study (ETDRS). ETDRS 26
    • Cusick M, Chew EY, Hoogwerf B, Agrón E, Wu L, Lindley A, et al. Risk factors for renal replacement therapy in the Early Treatment Diabetic Retinopathy Study (ETDRS). ETDRS 26. Kidney Int 2004; 66: 1173-9.
    • (2004) Kidney Int , vol.66 , pp. 1173-1179
    • Cusick, M.1    Chew, E.Y.2    Hoogwerf, B.3    Agrón, E.4    Wu, L.5    Lindley, A.6
  • 125
    • 42149096747 scopus 로고    scopus 로고
    • Predictors of development and progression of microvascular complications in a cohort of Brazilian type 2 diabetic patients
    • Cardoso CR, Salles GF Predictors of development and progression of microvascular complications in a cohort of Brazilian type 2 diabetic patients. J Diabetes Complic 2008; 22: 164-70.
    • (2008) J Diabetes Complic , vol.22 , pp. 164-170
    • Cardoso, C.R.1    Salles, G.F.2
  • 126
    • 0014519590 scopus 로고
    • A double-blind controlled trial of clofibrate in the treatment of diabetic retinopathy
    • Harrold BP, Marmion VJ, Gough KR. A double-blind controlled trial of clofibrate in the treatment of diabetic retinopathy. Diabetes 1969; 18: 285-91.
    • (1969) Diabetes , vol.18 , pp. 285-291
    • Harrold, B.P.1    Marmion, V.J.2    Gough, K.R.3
  • 127
    • 0013772025 scopus 로고
    • A controlled trial of Atromid therapy in exudative diabetic retinopathy
    • Cullen JF, Ireland JT and Oliver MF. A controlled trial of Atromid therapy in exudative diabetic retinopathy. Trans Ophth Soc UK 1964; 84: 281.
    • (1964) Trans Ophth Soc UK , vol.84 , pp. 281
    • Cullen, J.F.1    Ireland, J.T.2    Oliver, M.F.3
  • 129
    • 17744402260 scopus 로고
    • Exudative diabetic retinopathy. The use of clofibrate in the treatment of hard exudates using a reduced but prolonged dosage over several years
    • Article in French
    • Dorne PA. Exudative diabetic retinopathy. The use of clofibrate in the treatment of hard exudates using a reduced but prolonged dosage over several years Arch Ophtalmol (Paris) 1977; 37: 393-400. [Article in French]
    • (1977) Arch Ophtalmol (Paris) , vol.37 , pp. 393-400
    • Dorne, P.A.1
  • 130
    • 0028051624 scopus 로고
    • Regression of hard exudates in diabetic background retinopathy in therapy with etiofibrate antilipemic agent
    • Article in German
    • Freyberger H, Schifferdecker E, Schatz H. Regression of hard exudates in diabetic background retinopathy in therapy with etiofibrate antilipemic agent. Med Klin 1994; 89: 594-97 [Article in German].
    • (1994) Med Klin , vol.89 , pp. 594-597
    • Freyberger, H.1    Schifferdecker, E.2    Schatz, H.3
  • 131
    • 0035166933 scopus 로고    scopus 로고
    • Effect of lipid reduction on the progression of renal disease: A meta-analysis
    • Fried LF, Orchard TJ, Kasiske BL: Effect of lipid reduction on the progression of renal disease: A meta-analysis. Kidney Int 2001; 59: 260-9.
    • (2001) Kidney Int , vol.59 , pp. 260-269
    • Fried, L.F.1    Orchard, T.J.2    Kasiske, B.L.3
  • 132
    • 49749144405 scopus 로고    scopus 로고
    • Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease
    • Fried LF. Effects of HMG-CoA reductase inhibitors (statins) on progression of kidney disease. Kidney Int 2008; 74: 571-6
    • (2008) Kidney Int , vol.74 , pp. 571-576
    • Fried, L.F.1
  • 134
    • 14844292088 scopus 로고    scopus 로고
    • Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: Results from the Diabetes Atherosclerosis Intervention Study (DAIS)
    • for the DAIS Investigators
    • Ansquer JC, Foucher C, Rattier S, Taskinen M-R, Steiner G for the DAIS Investigators. Fenofibrate reduces progression to microalbuminuria over 3 years in a placebo-controlled study in type 2 diabetes: Results from the Diabetes Atherosclerosis Intervention Study (DAIS). Am J Kidney Dis 2005; 45: 485-93.
    • (2005) Am J Kidney Dis , vol.45 , pp. 485-493
    • Ansquer, J.C.1    Foucher, C.2    Rattier, S.3    Taskinen, M.-R.4    Steiner, G.5
  • 135
    • 0141617491 scopus 로고    scopus 로고
    • Effects of fenofibrate on albuminuria in participants with hypertriglyceridemia and/or hyperuricemia: A multicenter, randomised, double-blind, placebo-controlled, crossover study
    • for the fenofibrate study group
    • Kasumi T, Hirano T, Yoshino G for the fenofibrate study group: Effects of fenofibrate on albuminuria in participants with hypertriglyceridemia and/or hyperuricemia: A multicenter, randomised, double-blind, placebo-controlled, crossover study. Curr Ther Res Clin Exp 2003; 64: 434-46.
    • (2003) Curr Ther Res Clin Exp , vol.64 , pp. 434-446
    • Kasumi, T.1    Hirano, T.2    Yoshino, G.3
  • 136
    • 0031437734 scopus 로고    scopus 로고
    • Can reduction in hypertriglyceridaemia slow progression of microalbuminuria in patients with non-insulin-dependent diabetes mellitus?
    • Smulders YM, van Eeden AE, Stehouwer CD, Weijers RN, Slaats EH, Silberbusch J. Can reduction in hypertriglyceridaemia slow progression of microalbuminuria in patients with non-insulin-dependent diabetes mellitus? Eur J Clin Invest 1997; 27: 997-1002.
    • (1997) Eur J Clin Invest , vol.27 , pp. 997-1002
    • Smulders, Y.M.1    van Eeden, A.E.2    Stehouwer, C.D.3    Weijers, R.N.4    Slaats, E.H.5    Silberbusch, J.6
  • 138
    • 9444232789 scopus 로고    scopus 로고
    • Lipid lowering drugs prescription and the risk of peripheral neuropathy: An exploratory case-control study using automated databases
    • Corrao G, Zambon A, Bert L, Botteri E, Leoni O, Contiero P. Lipid lowering drugs prescription and the risk of peripheral neuropathy: An exploratory case-control study using automated databases. J Epidemiol Commun Health 2004; 58: 1047-51.
    • (2004) J Epidemiol Commun Health , vol.58 , pp. 1047-1051
    • Corrao, G.1    Zambon, A.2    Bert, L.3    Botteri, E.4    Leoni, O.5    Contiero, P.6
  • 139
    • 41149125988 scopus 로고    scopus 로고
    • Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: The Fremantle Diabetes Study
    • Davis TME, Yeap BB, Davis WA, Bruce DG. Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: The Fremantle Diabetes Study. Diabetologia 2008; 51: 562-6.
    • (2008) Diabetologia , vol.51 , pp. 562-566
    • Davis, T.M.E.1    Yeap, B.B.2    Davis, W.A.3    Bruce, D.G.4
  • 140
    • 12444318777 scopus 로고    scopus 로고
    • The need for a large-scale trial of fibrate therapy in diabetes: The rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
    • The FIELD Study Investigators
    • The FIELD Study Investigators. The need for a large-scale trial of fibrate therapy in diabetes: The rationale and design of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Cardiovasc Diabetol 2004: 3: 9.
    • (2004) Cardiovasc Diabetol , vol.3 , pp. 9
  • 141
    • 0348048874 scopus 로고    scopus 로고
    • Diabetic retinopathy
    • Frank RN. Diabetic retinopathy. N Engl J Med 2004; 350: 48-58.
    • (2004) N Engl J Med , vol.350 , pp. 48-58
    • Frank, R.N.1
  • 143
    • 7044228789 scopus 로고    scopus 로고
    • A central role for inflammation in the pathogenesis of diabetic retinopathy
    • Joussen AM, Poulaki V, Le ML, Koizumi K, Esser C, Janicki H, et al. A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 2004; 18: 1450-2.
    • (2004) FASEB J , vol.18 , pp. 1450-1452
    • Joussen, A.M.1    Poulaki, V.2    Le, M.L.3    Koizumi, K.4    Esser, C.5    Janicki, H.6
  • 145
    • 84856606464 scopus 로고    scopus 로고
    • Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy
    • Kern TS. Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp Diabetes Res 2007; 95: 103.
    • (2007) Exp Diabetes Res , vol.95 , pp. 103
    • Kern, T.S.1
  • 146
    • 0036174019 scopus 로고    scopus 로고
    • Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo
    • Joussen AM, Poulaki V, Qin W, Kirchhof B, Mitsiades N, Wiegand SJ, et al. Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo. Am J Pathol 2002; 160: 501-9.
    • (2002) Am J Pathol , vol.160 , pp. 501-509
    • Joussen, A.M.1    Poulaki, V.2    Qin, W.3    Kirchhof, B.4    Mitsiades, N.5    Wiegand, S.J.6
  • 147
    • 33845546564 scopus 로고    scopus 로고
    • Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy
    • Demircan N, Safran BG, Soylu M, Ozcan AA, Sizmaz S. Determination of vitreous interleukin-1 (IL-1) and tumour necrosis factor (TNF) levels in proliferative diabetic retinopathy. Eye 2006; 20: 1366-9.
    • (2006) Eye , vol.20 , pp. 1366-1369
    • Demircan, N.1    Safran, B.G.2    Soylu, M.3    Ozcan, A.A.4    Sizmaz, S.5
  • 148
    • 34247108235 scopus 로고    scopus 로고
    • Fenofibrate regulates retinal endothelial cell survival through the AMPK signal transduction pathway
    • Kim J, Ahn JH, Kim JH, Yu YS, Kim HS, Ha J, et al. Fenofibrate regulates retinal endothelial cell survival through the AMPK signal transduction pathway. Exp Eye Res 2007; 84: 886-93.
    • (2007) Exp Eye Res , vol.84 , pp. 886-893
    • Kim, J.1    Ahn, J.H.2    Kim, J.H.3    Yu, Y.S.4    Kim, H.S.5    Ha, J.6
  • 149
    • 41149095864 scopus 로고    scopus 로고
    • PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation
    • Okayasu T, Tomizawa A, Suzuki K, Manaka K, Hattori Y. PPARalpha activators upregulate eNOS activity and inhibit cytokine-induced NF-kappaB activation through AMP-activated protein kinase activation. Life Sci 2008; 82: 884-91.
    • (2008) Life Sci , vol.82 , pp. 884-891
    • Okayasu, T.1    Tomizawa, A.2    Suzuki, K.3    Manaka, K.4    Hattori, Y.5
  • 151
    • 0030319454 scopus 로고    scopus 로고
    • Malondialdehyde serum concentration in type 1 diabetic with and without retinopathy
    • Losada M, Alio JL. Malondialdehyde serum concentration in type 1 diabetic with and without retinopathy. Doc Ophthalmol 1996-1997; 93: 223-9.
    • (1996) Doc Ophthalmol , vol.93 , pp. 223-229
    • Losada, M.1    Alio, J.L.2
  • 152
    • 34547118091 scopus 로고    scopus 로고
    • Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury
    • Chen XR, Besson VC, Palmier B, Garcia Y, Plotkine M, Marchand-Leroux C. Neurological recovery-promoting, anti-inflammatory, and anti-oxidative effects afforded by fenofibrate, a PPAR alpha agonist, in traumatic brain injury. J Neurotrauma 2007; 24: 1119-31.
    • (2007) J Neurotrauma , vol.24 , pp. 1119-1131
    • Chen, X.R.1    Besson, V.C.2    Palmier, B.3    Garcia, Y.4    Plotkine, M.5    Marchand-Leroux, C.6
  • 153
    • 46449103466 scopus 로고    scopus 로고
    • Improvement of inflammatory responses associated with NF-kappaB pathway in kidneys from diabetic rats
    • Chen L, Zhang J, Zhang Y, Wang Y, Wang B. Improvement of inflammatory responses associated with NF-kappaB pathway in kidneys from diabetic rats. Inflamm Res 2008; 57(5): 199-204.
    • (2008) Inflamm Res , vol.57 , Issue.5 , pp. 199-204
    • Chen, L.1    Zhang, J.2    Zhang, Y.3    Wang, Y.4    Wang, B.5
  • 154
    • 33646508121 scopus 로고    scopus 로고
    • PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice
    • Park CW, Zhang Y, Zhang X, Wu J, Chen L, Cha DR, et al. PPARalpha agonist fenofibrate improves diabetic nephropathy in db/db mice. Kidney Int 2006; 69: 1511-7.
    • (2006) Kidney Int , vol.69 , pp. 1511-1517
    • Park, C.W.1    Zhang, Y.2    Zhang, X.3    Wu, J.4    Chen, L.5    Cha, D.R.6
  • 155
    • 45149118530 scopus 로고    scopus 로고
    • PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats
    • Zhao X, Li LY.PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and glomerular hypertrophy in Zucker diabetic fatty rats. Am J Nephrol 2008; 28: 598-606.
    • (2008) Am J Nephrol , vol.28 , pp. 598-606
    • Zhao, X.1    Li, L.Y.2
  • 157
    • 48949117573 scopus 로고    scopus 로고
    • Diabetes, cognitive function, and the blood-brain barrier
    • Huber JD. Diabetes, cognitive function, and the blood-brain barrier. Curr Pharm Des 2008; 14(16): 1594-600.
    • (2008) Curr Pharm Des , vol.14 , Issue.16 , pp. 1594-1600
    • Huber, J.D.1
  • 158
    • 44449100222 scopus 로고    scopus 로고
    • Role of advanced glycation end products (AGEs) and oxidative stress in diabetic retinopathy
    • Yamagishi S, Ueda S, Matsui T, Nakamura K, Okuda S. Role of advanced glycation end products (AGEs) and oxidative stress in diabetic retinopathy. Curr Pharm Des 2008; 14(10): 962-8.
    • (2008) Curr Pharm Des , vol.14 , Issue.10 , pp. 962-968
    • Yamagishi, S.1    Ueda, S.2    Matsui, T.3    Nakamura, K.4    Okuda, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.