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Volumn 13, Issue 6, 2014, Pages 345-356

Adaptive graph-based multiple testing procedures

Author keywords

Adaptive design; Graphical approach; Multiple comparisons; Multiple endpoints; Partial conditional error rate; Treatment selection

Indexed keywords

ALGORITHM; ANALYTIC METHOD; ARTICLE; CASE STUDY; CLINICAL TRIAL (TOPIC); CORRELATION COEFFICIENT; EFFECT SIZE; HUMAN; NORMAL DISTRIBUTION; NULL HYPOTHESIS; PROBABILITY; SAMPLE SIZE; SIMULATION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STATISTICS; STUDY DESIGN; METHODOLOGY; PROCEDURES; STATISTICS AND NUMERICAL DATA;

EID: 84911976013     PISSN: 15391604     EISSN: 15391612     Source Type: Journal    
DOI: 10.1002/pst.1640     Document Type: Article
Times cited : (16)

References (55)
  • 1
    • 79960812381 scopus 로고    scopus 로고
    • Testing non-inferiority and superiority for two endpoints for several treatments with a control
    • Lawrence J. Testing non-inferiority and superiority for two endpoints for several treatments with a control. Pharmaceutical Statistics 2011; 10(4):318-324.
    • (2011) Pharmaceutical Statistics , vol.10 , Issue.4 , pp. 318-324
    • Lawrence, J.1
  • 2
    • 84856554268 scopus 로고    scopus 로고
    • Multiple comparisons to both a negative and a positive control
    • Hasler M. Multiple comparisons to both a negative and a positive control. Pharmaceutical Statistics 2012; 11(1):74-81.
    • (2012) Pharmaceutical Statistics , vol.11 , Issue.1 , pp. 74-81
    • Hasler, M.1
  • 3
    • 84858441562 scopus 로고    scopus 로고
    • An evaluation of methods for testing hypotheses relating to two endpoints in a single clinical trial
    • Su T.L, Glimm E,Whitehead J, Branson M. An evaluation of methods for testing hypotheses relating to two endpoints in a single clinical trial. Pharmaceutical Statistics 2012; 11(2):107-117.
    • (2012) Pharmaceutical Statistics , vol.11 , Issue.2 , pp. 107-117
    • Su, T.L.1    Glimm, E.2    Whitehead, J.3    Branson, M.4
  • 4
    • 0141918127 scopus 로고    scopus 로고
    • EMA. European Medicines Agency: London, UK, [Accessed on 10 September 2014]
    • EMA. Points to consider on multiplicity issues in clinical trials. European Medicines Agency: London, UK, 2002. (Available from: http://www.ema.europa.eu/ema/pages/includes/document/open-document.jsp?webContentId=WC500003640) [Accessed on 10 September 2014].
    • (2002) Points to Consider on Multiplicity Issues in Clinical Trials
  • 5
    • 0007491434 scopus 로고    scopus 로고
    • ICH Steering Committee: Geneva, Switzerland, [Accessed on 10 September 2014]
    • ICH E9: statistical principles for clinical trials. ICH Steering Committee: Geneva, Switzerland, 1998. (Available from: http://www.ich.org/fileadmin/Public-Web-Site/ICH-Products/Guidelines/Efficacy/E9/Step4/E9-Guideline.pdf) [Accessed on 10 September 2014].
    • (1998) ICH E9: Statistical Principles for Clinical Trials
  • 7
    • 0030694389 scopus 로고    scopus 로고
    • Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear statistical significance
    • O'Neill RT. Secondary endpoints cannot be validly analyzed if the primary endpoint does not demonstrate clear statistical significance. Controlled Clinical Trials 1997; 18(6):550-556.
    • (1997) Controlled Clinical Trials , vol.18 , Issue.6 , pp. 550-556
    • O'neill, R.T.1
  • 8
    • 60749089513 scopus 로고    scopus 로고
    • A graphical approach to sequentially rejectivemultiple test procedures
    • Bretz F, Maurer W, Brannath W, Posch M. A graphical approach to sequentially rejectivemultiple test procedures. Statistics in Medicine 2009; 28(4):586-604.
    • (2009) Statistics in Medicine , vol.28 , Issue.4 , pp. 586-604
    • Bretz, F.1    Maurer, W.2    Brannath, W.3    Posch, M.4
  • 9
    • 64549084568 scopus 로고    scopus 로고
    • A recycling framework for the construction of Bonferroni-based multiple tests
    • Burman CF, Sonesson C, Guilbaud O. A recycling framework for the construction of Bonferroni-based multiple tests. Statistics in Medicine 2009; 28(5):739-761.
    • (2009) Statistics in Medicine , vol.28 , Issue.5 , pp. 739-761
    • Burman, C.F.1    Sonesson, C.2    Guilbaud, O.3
  • 10
    • 79956096307 scopus 로고    scopus 로고
    • Test and power considerations for multiple endpoint analyses using sequentially rejective graphical procedures
    • Bretz F, Maurer W, Hommel G. Test and power considerations for multiple endpoint analyses using sequentially rejective graphical procedures. Statistics in Medicine 2011; 30(13):1489-1501.
    • (2011) Statistics in Medicine , vol.30 , Issue.13 , pp. 1489-1501
    • Bretz, F.1    Maurer, W.2    Hommel, G.3
  • 11
    • 0032582081 scopus 로고    scopus 로고
    • Testing strategies in multi-dose experiments including active control
    • Bauer P, Roehmel J, Maurer W, Hothorn L. Testing strategies in multi-dose experiments including active control. Statistics in Medicine 1998; 17:2133-2146.
    • (1998) Statistics in Medicine , vol.17 , pp. 2133-2146
    • Bauer, P.1    Roehmel, J.2    Maurer, W.3    Hothorn, L.4
  • 12
    • 0043136549 scopus 로고    scopus 로고
    • Gatekeeping strategies for clinical trials that do not require all primary effects to be significant
    • Dmitrienko A, Offen WW, Westfall PH. Gatekeeping strategies for clinical trials that do not require all primary effects to be significant. Statistics in Medicine 2003; 22:2387-2400.
    • (2003) Statistics in Medicine , vol.22 , pp. 2387-2400
    • Dmitrienko, A.1    Offen, W.W.2    Westfall, P.H.3
  • 13
    • 0002676309 scopus 로고
    • Multiple comparisons in drug clinical trials and pre-clinical assays: A priori ordered hypotheses
    • Joachim Vollmar (ed.) Gustav Fischer Verlag: New York
    • Maurer W, Hothorn LA, LehmacherW.Multiple comparisons in drug clinical trials and pre-clinical assays: a priori ordered hypotheses. In Biometrie in der Chemisch-Pharmazeutischen Industrie, Joachim Vollmar (ed.) Gustav Fischer Verlag: New York; 1995; pp. 3-18.
    • (1995) Biometrie in der Chemisch-Pharmazeutischen Industrie , pp. 3-18
    • Maurer, W.1    Hothorn, L.A.2    Lehmacher, W.3
  • 14
    • 0042202937 scopus 로고    scopus 로고
    • Optimally weighted, fixed sequence, and gatekeeping multiple testing procedures
    • Westfall PH, Krishen A. Optimally weighted, fixed sequence, and gatekeeping multiple testing procedures. Journal of Statistical Planning and Inference 2001; 99:25-40.
    • (2001) Journal of Statistical Planning and Inference , vol.99 , pp. 25-40
    • Westfall, P.H.1    Krishen, A.2
  • 15
    • 33748538354 scopus 로고    scopus 로고
    • An adaptive hierarchical test procedure for selecting safe and efficient treatments
    • König F, Bauer P, Brannath W. An adaptive hierarchical test procedure for selecting safe and efficient treatments. Biometrical Journal 2006; 48(4):663-678.
    • (2006) Biometrical Journal , vol.48 , Issue.4 , pp. 663-678
    • König, F.1    Bauer, P.2    Brannath, W.3
  • 16
    • 15944368765 scopus 로고    scopus 로고
    • A fixed sequence Bonferroni procedure for testing multiple endpoints
    • Wiens BL. A fixed sequence Bonferroni procedure for testing multiple endpoints. Pharmaceutical Statistics 2003; 2(3):211-215.
    • (2003) Pharmaceutical Statistics , vol.2 , Issue.3 , pp. 211-215
    • Wiens, B.L.1
  • 17
    • 27544506961 scopus 로고    scopus 로고
    • The fallback procedure for evaluating a single family of hypotheses
    • Wiens BL, Dmitrienko A. The fallback procedure for evaluating a single family of hypotheses. Journal of Biopharmaceutical Statistics 2005; 15(6):929-942.
    • (2005) Journal of Biopharmaceutical Statistics , vol.15 , Issue.6 , pp. 929-942
    • Wiens, B.L.1    Dmitrienko, A.2
  • 18
    • 34548604912 scopus 로고    scopus 로고
    • Powerful short-cuts for multiple testing procedureswith special reference to gatekeeping strategies
    • Hommel G, Bretz F, Maurer W. Powerful short-cuts for multiple testing procedureswith special reference to gatekeeping strategies. Statistics in Medicine 2007; 26(22):4063-4073.
    • (2007) Statistics in Medicine , vol.26 , Issue.22 , pp. 4063-4073
    • Hommel, G.1    Bretz, F.2    Maurer, W.3
  • 19
    • 0017146303 scopus 로고
    • On closed testing procedures with special reference to ordered analysis of variance
    • Marcus R, Peritz E, Gabriel KR. On closed testing procedures with special reference to ordered analysis of variance. Biometrika 1976; 63(3):655-660.
    • (1976) Biometrika , vol.63 , Issue.3 , pp. 655-660
    • Marcus, R.1    Peritz, E.2    Gabriel, K.R.3
  • 23
    • 31344446475 scopus 로고    scopus 로고
    • The reassessment of trial perspectives from interimdata-A critical view
    • Bauer P, Koenig F. The reassessment of trial perspectives from interimdata-A critical view. Statistics in medicine 2006; 25(1):23-36.
    • (2006) Statistics in Medicine , vol.25 , Issue.1 , pp. 23-36
    • Bauer, P.1    Koenig, F.2
  • 24
    • 33646257465 scopus 로고    scopus 로고
    • Application of adaptive designs-A review
    • Bauer P, Einfalt J. Application of adaptive designs-A review. Biometrical journal 2006; 48(4):493-506.
    • (2006) Biometrical Journal , vol.48 , Issue.4 , pp. 493-506
    • Bauer, P.1    Einfalt, J.2
  • 25
    • 84861093363 scopus 로고    scopus 로고
    • Adaptive designs for single-arm phase II trials in oncology
    • Englert S, Kieser M. Adaptive designs for single-arm phase II trials in oncology. Pharmaceutical Statistics 2012; 11(3):241-249.
    • (2012) Pharmaceutical Statistics , vol.11 , Issue.3 , pp. 241-249
    • Englert, S.1    Kieser, M.2
  • 26
    • 84858449958 scopus 로고    scopus 로고
    • A practical comparison of blinded methods for sample size reviews in survival data clinical trials
    • Todd S, Valdés-Márquez E,West J. A practical comparison of blinded methods for sample size reviews in survival data clinical trials. Pharmaceutical Statistics 2012; 11(2):141-148.
    • (2012) Pharmaceutical Statistics , vol.11 , Issue.2 , pp. 141-148
    • Todd, S.1    Valdés-Márquez Ewest, J.2
  • 27
    • 84901187825 scopus 로고    scopus 로고
    • A review and re-interpretation of a group-sequential approach to sample size re-estimation in two-stage trials
    • Bowden J, Mander A. A review and re-interpretation of a group-sequential approach to sample size re-estimation in two-stage trials. Pharmaceutical Statistics 2014; 13(3):163-172.
    • (2014) Pharmaceutical Statistics , vol.13 , Issue.3 , pp. 163-172
    • Bowden, J.1    Mander, A.2
  • 28
    • 0033618626 scopus 로고    scopus 로고
    • Combining different phases in the development of medical treatments within a single trial
    • Bauer P, Kieser M. Combining different phases in the development of medical treatments within a single trial. Statistics in Medicine 1999; 18(14):1833-1848.
    • (1999) Statistics in Medicine , vol.18 , Issue.14 , pp. 1833-1848
    • Bauer, P.1    Kieser, M.2
  • 29
    • 0033434895 scopus 로고    scopus 로고
    • Inference on multiple endpoints in clinical trials with adaptive interim analyses
    • Kieser M, Bauer P, Lehmacher W. Inference on multiple endpoints in clinical trials with adaptive interim analyses. Biometrical Journal 1999; 41(3):261-277.
    • (1999) Biometrical Journal , vol.41 , Issue.3 , pp. 261-277
    • Kieser, M.1    Bauer, P.2    Lehmacher, W.3
  • 30
    • 0040374501 scopus 로고    scopus 로고
    • Adaptive modifications of hypotheses after an interim analysis
    • Hommel G. Adaptive modifications of hypotheses after an interim analysis. Biometrical Journal 2001; 43(5):581-589.
    • (2001) Biometrical Journal , vol.43 , Issue.5 , pp. 581-589
    • Hommel, G.1
  • 31
    • 30944469129 scopus 로고    scopus 로고
    • Testing and estimation in flexible group sequential designs with adaptive treatment selection
    • Posch M, Koenig F, Branson M, Brannath W, Dunger-Baldauf C, Bauer P. Testing and estimation in flexible group sequential designs with adaptive treatment selection. Statistics in Medicine 2005; 24(24):3697-3714.
    • (2005) Statistics in Medicine , vol.24 , Issue.24 , pp. 3697-3714
    • Posch, M.1    Koenig, F.2    Branson, M.3    Brannath, W.4    Dunger-Baldauf, C.5    Bauer, P.6
  • 33
    • 79956157675 scopus 로고    scopus 로고
    • An adaptive seamless phase II/III design for oncology trials with subpopulation selection using correlated survival endpoints
    • Jenkins M, Stone A, Jennison C. An adaptive seamless phase II/III design for oncology trials with subpopulation selection using correlated survival endpoints. Pharmaceutical Statistics 2011; 10(4):347-356.
    • (2011) Pharmaceutical Statistics , vol.10 , Issue.4 , pp. 347-356
    • Jenkins, M.1    Stone, A.2    Jennison, C.3
  • 35
    • 84870869525 scopus 로고    scopus 로고
    • A conditional error function approach for subgroup selection in adaptive clinical trials
    • Friede T, Parsons N, Stallard N. A conditional error function approach for subgroup selection in adaptive clinical trials. Statistics in Medicine 2012; 31(30):4309-4320.
    • (2012) Statistics in Medicine , vol.31 , Issue.30 , pp. 4309-4320
    • Friede, T.1    Parsons, N.2    Stallard, N.3
  • 36
    • 84904425514 scopus 로고    scopus 로고
    • Data-driven treatment selection for seamless phase ii/iii trials incorporating early-outcome data
    • Kunz CU, Friede T, Parsons N, Todd S, Stallard N. Data-driven treatment selection for seamless phase ii/iii trials incorporating early-outcome data. Pharmaceutical Statistics 2014; 13(4):238-246.
    • (2014) Pharmaceutical Statistics , vol.13 , Issue.4 , pp. 238-246
    • Kunz, C.U.1    Friede, T.2    Parsons, N.3    Todd, S.4    Stallard, N.5
  • 37
    • 84887412859 scopus 로고    scopus 로고
    • Optimizing trial design in pharmacogenetics research: Comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements
    • Boessen R, Baan F, Groenwold R, Egberts A, Klungel O, Grobbee D, Knol M, Roes K. Optimizing trial design in pharmacogenetics research: comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements. Pharmaceutical Statistics 2013; 12(6):366-374.
    • (2013) Pharmaceutical Statistics , vol.12 , Issue.6 , pp. 366-374
    • Boessen, R.1    Baan, F.2    Groenwold, R.3    Egberts, A.4    Klungel, O.5    Grobbee, D.6    Knol, M.7    Roes, K.8
  • 38
    • 84904500274 scopus 로고    scopus 로고
    • When is a seamless study desirable? Case studies fromdifferent pharmaceutical sponsors
    • Cuffe RL, Lawrence D, Stone A, Vandemeulebroecke M. When is a seamless study desirable? Case studies fromdifferent pharmaceutical sponsors. Pharmaceutical Statistics 2014; 13(4):229-237.
    • (2014) Pharmaceutical Statistics , vol.13 , Issue.4 , pp. 229-237
    • Cuffe, R.L.1    Lawrence, D.2    Stone, A.3    Vandemeulebroecke, M.4
  • 40
    • 84876970942 scopus 로고    scopus 로고
    • Partition testing in confirmatory adaptive designs with structured objectives
    • Sugitani T, Hamasaki T, Hamada C. Partition testing in confirmatory adaptive designs with structured objectives. Biometrical Journal 2013; 55(3):341-359.
    • (2013) Biometrical Journal , vol.55 , Issue.3 , pp. 341-359
    • Sugitani, T.1    Hamasaki, T.2    Hamada, C.3
  • 41
    • 42349113828 scopus 로고    scopus 로고
    • A uniform improvement of Bonferroni-type tests by sequential tests
    • Posch M, Futschik A. A uniform improvement of Bonferroni-type tests by sequential tests. Journal of the American Statistical Association 2008; 103(481):299-308.
    • (2008) Journal of the American Statistical Association , vol.103 , Issue.481 , pp. 299-308
    • Posch, M.1    Futschik, A.2
  • 42
    • 78249253755 scopus 로고    scopus 로고
    • Type i error rate control in adaptive designs for confirmatory clinical trials with treatment selection at interim
    • Posch M, Maurer W, Bretz F. Type I error rate control in adaptive designs for confirmatory clinical trials with treatment selection at interim. Pharmaceutical Statistics 2011; 10(2):96-104.
    • (2011) Pharmaceutical Statistics , vol.10 , Issue.2 , pp. 96-104
    • Posch, M.1    Maurer, W.2    Bretz, F.3
  • 43
    • 80755127019 scopus 로고    scopus 로고
    • Graphical approaches for multiple comparison procedures using weighted Bonferroni, simes, or parametric tests
    • Bretz F, Posch M, Glimm E, Klinglmueller F, Maurer W, Rohmeyer K. Graphical approaches for multiple comparison procedures using weighted Bonferroni, simes, or parametric tests. Biometrical Journal 2011; 53(6):894-913.
    • (2011) Biometrical Journal , vol.53 , Issue.6 , pp. 894-913
    • Bretz, F.1    Posch, M.2    Glimm, E.3    Klinglmueller, F.4    Maurer, W.5    Rohmeyer, K.6
  • 44
    • 70349234337 scopus 로고    scopus 로고
    • Flexible designs for genomewide association studies
    • Scherag A, Hebebrand J, Schäfer H, Müller HH. Flexible designs for genomewide association studies. Biometrics 2009; 65(3): 815-821.
    • (2009) Biometrics , vol.65 , Issue.3 , pp. 815-821
    • Scherag, A.1    Hebebrand, J.2    Schäfer, H.3    Müller, H.H.4
  • 45
    • 0029589385 scopus 로고
    • Designed extension of studies based on conditional power
    • Proschan MA, Hunsberger SA. Designed extension of studies based on conditional power. Biometrics 1995; 51:1315-1324.
    • (1995) Biometrics , vol.51 , pp. 1315-1324
    • Ma, P.1    Hunsberger, S.A.2
  • 46
    • 4344665155 scopus 로고    scopus 로고
    • A general statistical principle for changing a design any time during the course of a trial
    • Müller HH, Schäfer H. A general statistical principle for changing a design any time during the course of a trial. Statistics in Medicine 2004; 23(16):2497-2508.
    • (2004) Statistics in Medicine , vol.23 , Issue.16 , pp. 2497-2508
    • Müller, H.H.1    Schäfer, H.2
  • 51
    • 84863304598 scopus 로고    scopus 로고
    • R Core Team. R Foundation for Statistical Computing: Vienna, Austria .ISBN 3-900051-07-0 [Accessed on 10 September 2014]
    • R Core Team. R: a language and environment for statistical computing. R Foundation for Statistical Computing: Vienna, Austria, 2013. (Available from: http://www.R-project.org/). ISBN 3-900051-07-0 [Accessed on 10 September 2014].
    • (2013) R: A Language and Environment for Statistical Computing
  • 52
    • 11844299859 scopus 로고    scopus 로고
    • Conditional rejection probabilities of student's t-test and design adaptations
    • Posch M, Timmesfeld N, König F, Müller HH. Conditional rejection probabilities of student's t-test and design adaptations. Biometrical Journal 2004; 46(4):389-403.
    • (2004) Biometrical Journal , vol.46 , Issue.4 , pp. 389-403
    • Posch, M.1    Timmesfeld, N.2    König, F.3    Müller, H.H.4
  • 53
    • 0032732411 scopus 로고    scopus 로고
    • Adaptive sample size calculations in group sequential trials
    • Lehmacher W, Wassmer G. Adaptive sample size calculations in group sequential trials. Biometrics 1999; 55(4):1286-1290.
    • (1999) Biometrics , vol.55 , Issue.4 , pp. 1286-1290
    • Lehmacher, W.1    Wassmer, G.2
  • 54
    • 0033458198 scopus 로고    scopus 로고
    • Adaptive two stage designs and the conditional error function
    • Posch M, Bauer P. Adaptive two stage designs and the conditional error function. Biometrical Journal 1999; 41:689-696.
    • (1999) Biometrical Journal , vol.41 , pp. 689-696
    • Posch, M.1    Bauer, P.2
  • 55
    • 84889633483 scopus 로고    scopus 로고
    • Multiple testing in group sequential trials using graphical approaches
    • Maurer W, Bretz F. Multiple testing in group sequential trials using graphical approaches. Statistics in Biopharmaceutical Research 2013; 5(4):311-320.
    • (2013) Statistics in Biopharmaceutical Research , vol.5 , Issue.4 , pp. 311-320
    • Maurer, W.1    Bretz, F.2


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