A conditional error function approach for subgroup selection in adaptive clinical trials

Statistics in Medicine

Volumn 31, Issue 30, 2012, Pages 4309-4320

  Friede, T ^a   Parsons, N ^b   Stallard, N ^b  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Adaptive design; Closed test procedure; Combination test; Conditional error function; Short term endpoint; Subgroup selection

Indexed keywords

ARTICLE; CASE STUDY; CLINICAL TRIAL (TOPIC); CONDITIONAL ERROR FUNCTION; HUMAN; INTERMETHOD COMPARISON; MOLECULARLY TARGETED THERAPY; NORMAL DISTRIBUTION; PROGRESSION FREE SURVIVAL; SIMULATION; STATISTICAL CONCEPTS;

CLINICAL TRIALS AS TOPIC; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DISEASE-FREE SURVIVAL; EFFECT MODIFIER, EPIDEMIOLOGIC; HUMANS; INDIVIDUALIZED MEDICINE; MOLECULAR TARGETED THERAPY; NEOPLASMS; OUTCOME ASSESSMENT (HEALTH CARE); PATIENT SELECTION; RESEARCH DESIGN; TIME FACTORS;

EID: 84870869525     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.5541     Document Type: Article

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