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Volumn 47, Issue 3, 2014, Pages 764-771

Neferine prevented hyperglycemia-induced endothelial cell apoptosis through suppressing ROS/Akt/NF-κB signal

Author keywords

Apoptosis; HUVECs; Neferine; ROS

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ASCORBIC ACID; CASPASE 3; CYTOCHROME C; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEFERINE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; PYRROLIDINE DITHIOCARBAMATE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; BENZYLISOQUINOLINE DERIVATIVE;

EID: 84911966110     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-014-0186-1     Document Type: Article
Times cited : (53)

References (19)
  • 1
    • 47749083574 scopus 로고    scopus 로고
    • Self-monitoring of blood glucose levels in patients with type 2 diabetes mellitus not taking insulin: a meta-analysis
    • PID: 18611098
    • A. Towfigh, M. Romanova, J.E. Weinreb, B. Munjas, M.J. Suttorp, A. Zhou, P.G. Shekelle, Self-monitoring of blood glucose levels in patients with type 2 diabetes mellitus not taking insulin: a meta-analysis. Am. J. Manag. Care 14, 468–475 (2008)
    • (2008) Am. J. Manag. Care , vol.14 , pp. 468-475
    • Towfigh, A.1    Romanova, M.2    Weinreb, J.E.3    Munjas, B.4    Suttorp, M.J.5    Zhou, A.6    Shekelle, P.G.7
  • 2
    • 78851472527 scopus 로고    scopus 로고
    • Effect of linagliptin monotherapy on glycaemic control and markers of beta-cell function in patients with inadequately controlled type 2 diabetes: a randomized controlled trial
    • PID: 21205122
    • S. Del Prato, A.H. Barnett, H. Huisman, D. Neubacher, H.J. Woerle, K.A. Dugi, Effect of linagliptin monotherapy on glycaemic control and markers of beta-cell function in patients with inadequately controlled type 2 diabetes: a randomized controlled trial. Diabetes Obes. Metab. 13, 258–267 (2011)
    • (2011) Diabetes Obes. Metab , vol.13 , pp. 258-267
    • Del Prato, S.1    Barnett, A.H.2    Huisman, H.3    Neubacher, D.4    Woerle, H.J.5    Dugi, K.A.6
  • 3
    • 0032485927 scopus 로고    scopus 로고
    • Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
    • COI: 1:CAS:528:DyaK1cXjsVSrsb8%3D, PID: 9591763
    • S.B. Williams, A.B. Goldfine, F.K. Timimi, H.H. Ting, M.A. Roddy, D.C. Simonson, M.A. Creager, Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo. Circulation 97, 1695–1701 (1998)
    • (1998) Circulation , vol.97 , pp. 1695-1701
    • Williams, S.B.1    Goldfine, A.B.2    Timimi, F.K.3    Ting, H.H.4    Roddy, M.A.5    Simonson, D.C.6    Creager, M.A.7
  • 4
    • 9444224416 scopus 로고    scopus 로고
    • Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart
    • COI: 1:CAS:528:DC%2BD2cXhtVOls7nE, PID: 15561951
    • D.D. Belke, E.A. Swanson, W.H. Dillmann, Decreased sarcoplasmic reticulum activity and contractility in diabetic db/db mouse heart. Diabetes 53, 3201–3208 (2004)
    • (2004) Diabetes , vol.53 , pp. 3201-3208
    • Belke, D.D.1    Swanson, E.A.2    Dillmann, W.H.3
  • 5
    • 27844593740 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway
    • COI: 1:CAS:528:DC%2BD2MXht1GhsLzF, PID: 15970429
    • F.M. Ho, W.W. Lin, B.C. Chen, C.M. Chao, C.R. Yang, L.Y. Lin, C.C. Lai, S.H. Liu, C.S. Liau, High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell. Signal. 18, 391–399 (2006)
    • (2006) Cell. Signal , vol.18 , pp. 391-399
    • Ho, F.M.1    Lin, W.W.2    Chen, B.C.3    Chao, C.M.4    Yang, C.R.5    Lin, L.Y.6    Lai, C.C.7    Liu, S.H.8    Liau, C.S.9
  • 6
    • 14644425394 scopus 로고    scopus 로고
    • High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway
    • COI: 1:CAS:528:DC%2BD2MXhtl2ku7w%3D, PID: 15653566
    • M.L. Sheu, F.M. Ho, R.S. Yang, K.F. Chao, W.W. Lin, S.Y. Lin-Shiau, S.H. Liu, High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arterioscler. Thromb. Vasc. Biol. 25, 539–545 (2005)
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , pp. 539-545
    • Sheu, M.L.1    Ho, F.M.2    Yang, R.S.3    Chao, K.F.4    Lin, W.W.5    Lin-Shiau, S.Y.6    Liu, S.H.7
  • 7
    • 21344462345 scopus 로고    scopus 로고
    • Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process
    • COI: 1:CAS:528:DC%2BD2MXmtVeltrY%3D, PID: 15983220
    • D. Detaille, B. Guigas, C. Chauvin, C. Batandier, E. Fontaine, N. Wiernsperger, X. Leverve, Metformin prevents high-glucose-induced endothelial cell death through a mitochondrial permeability transition-dependent process. Diabetes 54, 2179–2187 (2005)
    • (2005) Diabetes , vol.54 , pp. 2179-2187
    • Detaille, D.1    Guigas, B.2    Chauvin, C.3    Batandier, C.4    Fontaine, E.5    Wiernsperger, N.6    Leverve, X.7
  • 8
    • 84862831138 scopus 로고    scopus 로고
    • Neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 MAPK-mediated p21 stabilization
    • COI: 1:CAS:528:DC%2BC38Xhs1Ggtrs%3D, PID: 22227330
    • X. Zhang, Z. Liu, B. Xu, Z. Sun, Y. Gong, C. Shao, Neferine, an alkaloid ingredient in lotus seed embryo, inhibits proliferation of human osteosarcoma cells by promoting p38 MAPK-mediated p21 stabilization. Eur. J. Pharmacol. 677, 47–54 (2012)
    • (2012) Eur. J. Pharmacol , vol.677 , pp. 47-54
    • Zhang, X.1    Liu, Z.2    Xu, B.3    Sun, Z.4    Gong, Y.5    Shao, C.6
  • 9
    • 84866867861 scopus 로고    scopus 로고
    • Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells
    • COI: 1:CAS:528:DC%2BC38Xhs1WitrzN, PID: 23122111
    • P. Poornima, R.S. Quency, V.V. Padma, Neferine induces reactive oxygen species mediated intrinsic pathway of apoptosis in HepG2 cells. Food Chem. 136, 659–667 (2013)
    • (2013) Food Chem , vol.136 , pp. 659-667
    • Poornima, P.1    Quency, R.S.2    Padma, V.V.3
  • 10
    • 4644339570 scopus 로고    scopus 로고
    • Multidrug resistance reversal in human gastric carcinoma cells by neferine
    • COI: 1:CAS:528:DC%2BD2cXptFSlt7k%3D, PID: 15378795
    • J.G. Cao, X.Q. Tang, S.H. Shi, Multidrug resistance reversal in human gastric carcinoma cells by neferine. World J. Gastroenterol. 10, 3062–3064 (2004)
    • (2004) World J. Gastroenterol , vol.10 , pp. 3062-3064
    • Cao, J.G.1    Tang, X.Q.2    Shi, S.H.3
  • 11
    • 67349276613 scopus 로고    scopus 로고
    • Neferine enhances insulin sensitivity in insulin resistant rats
    • COI: 1:CAS:528:DC%2BD1MXnt1Cjtb0%3D, PID: 19527823
    • Y. Pan, B. Cai, K. Wang, S. Wang, S. Zhou, X. Yu, B. Xu, L. Chen, Neferine enhances insulin sensitivity in insulin resistant rats. J. Ethnopharmacol. 124, 98–102 (2009)
    • (2009) J. Ethnopharmacol , vol.124 , pp. 98-102
    • Pan, Y.1    Cai, B.2    Wang, K.3    Wang, S.4    Zhou, S.5    Yu, X.6    Xu, B.7    Chen, L.8
  • 12
    • 73449146238 scopus 로고    scopus 로고
    • Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis
    • COI: 1:CAS:528:DC%2BC3cXksVejug%3D%3D, PID: 19909737
    • L. Zhao, X. Wang, Q. Chang, J. Xu, Y. Huang, Q. Guo, S. Zhang, W. Wang, X. Chen, J. Wang, Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. Eur. J. Pharmacol. 627, 304–312 (2010)
    • (2010) Eur. J. Pharmacol , vol.627 , pp. 304-312
    • Zhao, L.1    Wang, X.2    Chang, Q.3    Xu, J.4    Huang, Y.5    Guo, Q.6    Zhang, S.7    Wang, W.8    Chen, X.9    Wang, J.10
  • 13
    • 0031290816 scopus 로고    scopus 로고
    • Effects of neferine on platelet aggregation in rabbits
    • COI: 1:CAS:528:DyaK2sXms1Ghu7w%3D, PID: 11243209
    • J. Yu, W.S. Hu, Effects of neferine on platelet aggregation in rabbits. Yao Xue Xue Bao 32(1), 1–4 (1997)
    • (1997) Yao Xue Xue Bao , vol.32 , Issue.1 , pp. 1-4
    • Yu, J.1    Hu, W.S.2
  • 14
    • 0032588317 scopus 로고    scopus 로고
    • NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
    • COI: 1:CAS:528:DyaK1MXlslSqurw%3D, PID: 10454539
    • C.Y. Wang, D.C. Guttridge, M.W. Mayo, A.S. Baldwin Jr, NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol. Cell. Biol. 19, 5923–5929 (1999)
    • (1999) Mol. Cell. Biol , vol.19 , pp. 5923-5929
    • Wang, C.Y.1    Guttridge, D.C.2    Mayo, M.W.3    Baldwin, A.S.4
  • 15
    • 0035714568 scopus 로고    scopus 로고
    • Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells
    • COI: 1:CAS:528:DC%2BD3MXjvFWltbk%3D, PID: 11358951
    • K. Yamamoto, R. Morishita, S. Hayashi, H. Matsushita, H. Nakagami, A. Moriguchi, K. Matsumoto, T. Nakamura, Y. Kaneda, T. Ogihara, Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells. Hypertension 37, 1341–1348 (2001)
    • (2001) Hypertension , vol.37 , pp. 1341-1348
    • Yamamoto, K.1    Morishita, R.2    Hayashi, S.3    Matsushita, H.4    Nakagami, H.5    Moriguchi, A.6    Matsumoto, K.7    Nakamura, T.8    Kaneda, Y.9    Ogihara, T.10
  • 16
    • 84880712614 scopus 로고    scopus 로고
    • Protective effect of neferine against isoproterenol-induced cardiac toxicity
    • COI: 1:CAS:528:DC%2BC3sXms1Ggt7Y%3D, PID: 23274852
    • G. Lalitha, P. Poornima, A. Archanah, V.V. Padma, Protective effect of neferine against isoproterenol-induced cardiac toxicity. Cardiovasc. Toxicol. 13, 168–179 (2013)
    • (2013) Cardiovasc. Toxicol , vol.13 , pp. 168-179
    • Lalitha, G.1    Poornima, P.2    Archanah, A.3    Padma, V.V.4
  • 17
    • 46749156297 scopus 로고    scopus 로고
    • Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
    • COI: 1:CAS:528:DC%2BD1cXot1Wisrc%3D, PID: 18440987
    • T. Yu, S.S. Sheu, J.L. Robotham, Y. Yoon, Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species. Cardiovasc. Res. 79, 341–351 (2008)
    • (2008) Cardiovasc. Res , vol.79 , pp. 341-351
    • Yu, T.1    Sheu, S.S.2    Robotham, J.L.3    Yoon, Y.4
  • 18
    • 43249088314 scopus 로고    scopus 로고
    • Blockade of chronic high glucose-induced endothelial apoptosis by Sasa borealis bamboo extract
    • COI: 1:CAS:528:DC%2BD1cXlsF2htr4%3D
    • Y.J. Choi, H.S. Lim, J.S. Choi, S.Y. Shin, J.Y. Bae, S.W. Kang, I.J. Kang, Y.H. Kang, Blockade of chronic high glucose-induced endothelial apoptosis by Sasa borealis bamboo extract. Exp. Biol. Med. (Maywood) 233, 580–591 (2008)
    • (2008) Exp. Biol. Med. (Maywood) , vol.233 , pp. 580-591
    • Choi, Y.J.1    Lim, H.S.2    Choi, J.S.3    Shin, S.Y.4    Bae, J.Y.5    Kang, S.W.6    Kang, I.J.7    Kang, Y.H.8
  • 19
    • 84884538218 scopus 로고    scopus 로고
    • Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells
    • COI: 1:CAS:528:DC%2BC3sXhtlGksL7F, PID: 23993526
    • P. Poornima, C.F. Weng, V.V. Padma, Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells. Food Chem. 141, 3598–3605 (2013)
    • (2013) Food Chem , vol.141 , pp. 3598-3605
    • Poornima, P.1    Weng, C.F.2    Padma, V.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.