Role of ERK1/2 MAPK signaling in the maintenance of myelin and axonal integrity in the adult CNS

Journal of Neuroscience

Volumn 34, Issue 48, 2014, Pages 16031-16045

  Ishii, Akihiro ^a   Furusho, Miki ^a   Dupree, Jeffrey L ^b   Bansal, Rashmi ^a  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Myelin; Oligodendrocytes

Indexed keywords

2', 3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; CALCIUM BINDING PROTEIN; CASPASE 3; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; GANGLIOSIDE GALACTOSYLTRANSFERASE; GLIAL FIBRILLARY ACIDIC PROTEIN; IONIZED CALCIUM BINDING ADAPTER MOLECULE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MYRF; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; ASTROCYTOSIS; CELL PROLIFERATION; CELL VIABILITY ASSAY; CENTRAL GRAY MATTER; CENTRAL NERVOUS SYSTEM FUNCTION; CONTROLLED STUDY; DOWN REGULATION; ELECTRON MICROSCOPY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; IMMUNOFLUORESCENCE; INTRACELLULAR SIGNALING; MALE; MICROGLIA; MOTOR DYSFUNCTION; MOUSE; MRNA EXPRESSION ASSAY; MYELIN SHEATH; MYELINATION; NERVE FIBER DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; OLIGODENDROGLIA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTAROD TEST; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SPINAL CORD VENTRAL HORN; TRANSGENIC MOUSE; UPREGULATION; WHITE MATTER; AGE; ANIMAL; AXON; BRAIN; CENTRAL NERVOUS SYSTEM; CYTOLOGY; KNOCKOUT MOUSE; PHYSIOLOGY; SPINAL CORD;

AGE FACTORS; ANIMALS; AXONS; BRAIN; CENTRAL NERVOUS SYSTEM; MAP KINASE SIGNALING SYSTEM; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MYELIN SHEATH; OLIGODENDROGLIA; SPINAL CORD;

EID: 84911928769     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3360-14.2014     Document Type: Article

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