Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination

Journal of Neuroscience

Volumn 34, Issue 13, 2014, Pages 4453-4465

  Wahl, Stacey E ^a   McLane, Lauren E ^a   Bercury, Kathryn K ^b   Macklin, Wendy B ^b   Wood, Teresa L ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Differentiation; mTOR; Myelination; Oligodendrocyte; Signaling

Indexed keywords

GREEN FLUORESCENT PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MYELIN; MYELIN ASSOCIATED GLYCOPROTEIN; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN; PROTEOLIPID PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; CEREBELLUM; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; MYELINATION; NONHUMAN; OLIGODENDROGLIA; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; SPINAL CORD; WESTERN BLOTTING;

DIFFERENTIATION; MTOR; MYELINATION; OLIGODENDROCYTE; SIGNALING;

2',3'-CYCLIC NUCLEOTIDE 3'-PHOSPHODIESTERASE; AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CELL COUNT; CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GREEN FLUORESCENT PROTEINS; INTEGRASES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MYELIN PROTEINS; MYELIN SHEATH; OLIGODENDROGLIA; TOR SERINE-THREONINE KINASES;

EID: 84897826499     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4311-13.2014     Document Type: Article

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