Channel cytoplasmic loops alter voltage-dependent sodium channel activation in an isoform-specific manner

Journal of Physiology

Volumn 535, Issue 2, 2001, Pages 371-381

  Bennett, Eric S ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; PAPAIN; SODIUM CHANNEL; SODIUM ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHANNEL GATING; CHIMERA; CONTROLLED STUDY; CYTOPLASM; DEPOLARIZATION; ELECTRIC POTENTIAL; HEART; HUMAN; HYPERPOLARIZATION; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE;

ANIMALS; CHO CELLS; CRICETINAE; CYTOPLASM; HUMANS; ION CHANNEL GATING; ISOMERISM; MEMBRANE POTENTIALS; MUSCLE, SKELETAL; MYOCARDIUM; PAPAIN; PATCH-CLAMP TECHNIQUES; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SODIUM CHANNELS;

EID: 0035449511     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.t01-1-00371.x     Document Type: Article

References (44)

1. Mechanism of modulation of the voltage-gated skeletal and cardiac muscle sodium channels by fatty acids
2. Contribution of sialic acid to the voltage dependence of sodium channel gating: A possible electrostatic mechanism
3. + channels
4. Molecular mechanism for an inherited cardiac arrhythmia
5. A sodium channel defect in hyperkalemic periodic paralysis: Potassium-induced failure of inactivation
6. Structure and function of voltage-gated ion channels
7. Electrophysiological characteristics of cloned skeletal and cardiac muscle sodium channels
8. Sodium channel mutations in paramyotonia congenita uncouple inactivation from activation
9. Emerging roles for cysteine proteases in human biology
10. Chimeric study of sodium channels from rat skeletal and cardiac muscle
11. Calcium-activated neutral protease (Calpain) system: Structure, function, and regulation
12. + channel mutation causing hyperkalemic periodic paralysis
13. Electrophysiological study of chimeric sodium channels from heart and skeletal muscle
14. Insertion of a SNS-specific tetrapeptide in S3-S4 linker of D4 accelerates recovery from inactivation of skeletal muscle voltage-gated Na channel μ 1 in HEK293 cell
15. 3 subunit
16. + channel-linked long-QT syndrome
17. + channels expressed in a mammalian cell line
18. Resurgence of sodium channel research
19. Inactivation defects caused by myotonia-associated mutations in the sodium channel III-IV linker
20. Normal and abnormal consequences of apoptosis in the human heart
21. Cloned potassium channels from eukaryotes and prokaryotes
22. Paramyotonia congenita mutations reveal different roles for segments S3 and S4 of domain D4 in hSkM1 sodium channel gating
23. Structure, function and expression of voltage-dependent sodium channels
24. Proteolytic activities that mediate apoptosis
25. Single-channel analysis of inactivation-defective rat skeletal muscle sodium channels containing the F1304Q mutation
26. + channel mutation in adult human skeletal muscle
27. + channels
28. Structure and function of voltage-gated sodium channels
29. + channels
30. Caspases: The proteases of the apoptotic pathway
31. Functional association of the beta 1 subunit with human cardiac (hH1) and rat skeletal muscle (mu1) sodium channel alpha subunit expressed in Xenopus oocytes
32. Cardiac sodium channels (hH1) are intrinsically more sensitive to block by lidocaine than are skeletal muscle (mu 1) channels
33. Characterisation of the isoform-specific differences in the gating of neuronal and muscle sodium channels
34. + channel chimaeras
35. Mutations in an S4 segment of the adult skeletal muscle sodium channel cause paramyotonia congenita
36. Identification of a mutation in the gene causing hyperkalemic periodic paralysis
37. Voltage- and frequency-dependent pentobarbital suppression of brain and muscle sodium channels expressed in a mammalian cell line
38. Calpain: New perspectives in molecular diversity and physiological-pathological involvement
39. Gating of skeletal and cardiac muscle sodium channels in mammalian cells
40. Structural determinants of slow inactivation in human cardiac and skeletal muscle sodium channels
41. Comparison of heterologously expressed human cardiac and skeletal muscle sodium channel
42. + channel mutations in the congenital long QT syndrome
43. + channel
44. Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity