Triiodothyronine activates lactate oxidation without impairing fatty acid oxidation and improves weaning from extracorporeal membrane oxygenation

Circulation Journal

Volumn 78, Issue 12, 2014, Pages 2867-2875

  Kajimoto, Masaki ^a   Ledee, Dolena R ^a   Xu, Chun ^a   Kajimoto, Hidemi ^a   Isern, Nancy G ^b   Portman, Michael A ^a,c  

^a SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

ECMO; Myocardial metabolism; Pediatric

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; FATTY ACID; LACTIC ACID; LIOTHYRONINE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PYRUVATE DEHYDROGENASE; PYRUVIC ACID; TROPONIN I; LACTIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CARBOXYLATION; CITRIC ACID CYCLE; CONTROLLED STUDY; CORONARY ARTERY OCCLUSION; EXTRACORPOREAL MEMBRANE OXYGENATION DEVICE; FATTY ACID OXIDATION; HEART FUNCTION; HEART INJURY; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE INJURY; HEART MUSCLE METABOLISM; HEART MUSCLE OXYGEN CONSUMPTION; HEART OUTPUT; ISOTOPE LABELING; LIOTHYRONINE BLOOD LEVEL; MALE; METABOLIC FLUX ANALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PHOSPHATE METABOLISM; PIGLET; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; REPERFUSION INJURY; SURVIVAL; WESTERN BLOTTING; ANIMAL; ARTIFICIAL VENTILATION; BIOSYNTHESIS; DRUG EFFECTS; DRUG SCREENING; EXTRACORPOREAL OXYGENATION; HEART CONTRACTION; HEART MUSCLE; HEMODYNAMICS; METABOLISM; MYOCARDIAL REPERFUSION INJURY; OXIDATION REDUCTION REACTION; OXYGEN CONSUMPTION; PIG; PROCEDURES; RANDOMIZATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CITRIC ACID CYCLE; DRUG EVALUATION; EXTRACORPOREAL MEMBRANE OXYGENATION; FATTY ACIDS; HEMODYNAMICS; LACTATES; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; PYRUVIC ACID; RANDOM ALLOCATION; SUS SCROFA; SWINE; TRIIODOTHYRONINE; VENTILATOR WEANING;

EID: 84911892969     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-14-0821     Document Type: Article

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