FUTSCH/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis

Journal of Neuroscience

Volumn 34, Issue 48, 2014, Pages 15962-15974

  Coyne, Alyssa N ^a   Siddegowda, Bhavani Bagevalu ^a   Estes, Patricia S ^a   Johannesmeyer, Jeffrey ^a   Kovalik, Tina ^c   Daniel, Scott G ^a   Pearson, Antony ^a   Bowser, Robert ^c   Zarnescu, Daniela C ^a,b  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

Microtubule stability; Neuromuscular junction; RNA metabolism

Indexed keywords

ALPHA TUBULIN; FUTSCH PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; MICROTUBULE ASSOCIATED PROTEIN 5; RIBONUCLEOPROTEIN; TAR DNA BINDING PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; DROSOPHILA PROTEIN; FUTSCH PROTEIN, DROSOPHILA; MAP1B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; TBPH PROTEIN, DROSOPHILA;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DROSOPHILA; FEMALE; GANGLION; GENE OVEREXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; LARVA; MALE; MICROTUBULE; MOTONEURON; NEUROMUSCULAR SYNAPSE; NEUROPROTECTION; NONHUMAN; PERIKARYON; POLYMERASE CHAIN REACTION; POLYSOME; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION; SPINAL CORD; TDP 43 PROTEINOPATHY; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; GENE TARGETING; GENETICS; METABOLISM; MIDDLE AGED; PROCEDURES; TRANSGENIC ANIMAL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE TARGETING; HUMANS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; RNA, MESSENGER;

EID: 84911877805     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2526-14.2014     Document Type: Article

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