Absence of mature microRNAs inactivates the response of gene expression to carcinogenesis induced by N-ethyl-N-nitrosourea in mouse liver

Journal of Applied Toxicology

Volumn 34, Issue 12, 2014, Pages 1409-1417

  Luan, Yang ^a   Qi, Xinming ^b   Xu, Liang ^c   Ren, Jin ^b   Chen, Tao ^d  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c Zhangjiang Hi Tech Park   (China)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Carcinogenesis; Dicer1 knockout; Gene expression; Microarray; MicroRNAs

Indexed keywords

BRCA1 PROTEIN; DICER; ETHYLNITROSOUREA; MICRORNA; PROTEIN P53; BRAP PROTEIN, MOUSE; DEAD BOX PROTEIN; DICER1 PROTEIN, MOUSE; RIBONUCLEASE III; TRANSCRIPTOME; UBIQUITIN PROTEIN LIGASE;

AGE; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CONTROLLED STUDY; GENE EXPRESSION; GENE FUNCTION; GENOMICS; HISTOPATHOLOGY; KNOCKOUT MOUSE; LIVER CARCINOGENESIS; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; WILD TYPE MOUSE; ANIMAL; CHEMICALLY INDUCED; CLUSTER ANALYSIS; DRUG EFFECTS; EXPERIMENTAL LIVER NEOPLASM; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; PRINCIPAL COMPONENT ANALYSIS;

ANIMALS; CLUSTER ANALYSIS; DEAD-BOX RNA HELICASES; ETHYLNITROSOUREA; GENE EXPRESSION PROFILING; LIVER NEOPLASMS, EXPERIMENTAL; MICE, KNOCKOUT; MICRORNAS; PRINCIPAL COMPONENT ANALYSIS; RIBONUCLEASE III; SIGNAL TRANSDUCTION; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES;

EID: 84911805163     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2973     Document Type: Article

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