Eupatorin-induced cell death in human leukemia cells is dependent on caspases and activates the mitogen- Activated protein kinase pathway

PLoS ONE

Volumn 9, Issue 11, 2014, Pages

  Vez, Sara Esté ^a   Marrero, María Teresa ^a   Quintana, José ^a   Vez, Francisco Esté ^a  

^a UNIVERSITY OF LAS PALMAS DE GRAN CANARIA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; EUPATORIN; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; ANTINEOPLASTIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; LEUKEMIA CELL; MITOCHONDRION; PROTEIN CLEAVAGE; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL DIVISION; CELL PROLIFERATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HL 60 CELL LINE; METABOLISM; PHOSPHORYLATION; PROTEIN DEGRADATION; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASES; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; FLAVONOIDS; G2 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEOLYSIS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84911473409     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0112536     Document Type: Article

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