Physiologically-based toxicokinetic model for cadmium using markov-chain monte carlo analysis of concentrations in blood, urine, and kidney cortex from living kidney donors

Toxicological Sciences

Volumn 141, Issue 2, 2014, Pages 365-376

  Fransson, Martin Niclas ^a   Barregard, Lars ^b   Sallsten, Gerd ^b   Akerstrom, Magnus ^b   Johanson, Gunnar ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cadmium; Exposure assessment; Physiologically based pharmacokinetics

Indexed keywords

CADMIUM; FERRITIN;

ADULT; AGED; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BODY WEIGHT; FEMALE; FERRITIN BLOOD LEVEL; HALF LIFE TIME; HUMAN; HUMAN TISSUE; KIDNEY CONCENTRATING CAPACITY; KIDNEY CORTEX; KIDNEY DONOR; MALE; MONTE CARLO METHOD; NORMAL HUMAN; PHYSIOLOGICALLY BASED TOXICOKINETIC; PROBABILITY; SMOKING; TOXICOKINETICS; URINARY EXCRETION; BIOLOGICAL MODEL; BLOOD; BODY BURDEN; COMPUTER SIMULATION; KIDNEY TRANSPLANTATION; LIVING DONOR; METABOLISM; MIDDLE AGED; PROCEDURES; REPRODUCIBILITY; RISK ASSESSMENT; URINE; YOUNG ADULT;

ADULT; AGED; BODY BURDEN; CADMIUM; COMPUTER SIMULATION; FEMALE; FERRITINS; HALF-LIFE; HUMANS; KIDNEY CORTEX; KIDNEY TRANSPLANTATION; LIVING DONORS; MALE; MARKOV CHAINS; MIDDLE AGED; MODELS, BIOLOGICAL; MONTE CARLO METHOD; RENAL ELIMINATION; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; TOXICOKINETICS; YOUNG ADULT;

EID: 84911473407     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu129     Document Type: Article

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