Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation

ACS Chemical Biology

Volumn 7, Issue 8, 2012, Pages 1367-1376

  Scheck, Rebecca A ^a   Lowder, Melissa A ^a   Appelbaum, Jacob S ^b   Schepartz, Alanna ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIPARTITE TETRACYSTEINE; CYSTEINE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BIOTINYLATION; CELL LABELING; CELL MEMBRANE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; CYTOSOL; ENDOCYTOSIS; ENZYME ACTIVATION; INTERNALIZATION; LIGAND BINDING; MAMMAL CELL; NONHUMAN; PLASTICITY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; SURFACE PROPERTY;

ALLOSTERIC SITE; ANIMALS; BINDING SITES; BIOCHEMISTRY; CELL MEMBRANE; CHO CELLS; CRICETINAE; CYSTEINE; DIMERIZATION; EPIDERMAL GROWTH FACTOR; HUMANS; LIGANDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 84865238071     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300216f     Document Type: Article

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