Compensatory frontoparietal activity during working memory: An endophenotype of obsessive-compulsive disorder

Biological Psychiatry

Volumn 76, Issue 11, 2014, Pages 878-887

  De Vries, Froukje E ^a   De Wit, Stella J ^a   Cath, Danielle C ^b,c   Van Der Werf, Ysbrand D ^a,d,e   Van Der Borden, Vionne ^a   Van Rossum, Thomas B ^a   Van Balkom, Anton J L M ^a   Van Der Wee, Nic J A ^f   Veltman, Dick J ^a   Van Den Heuvel, Odile A ^a,d  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b Altrecht Academic Anxiety Center   (Netherlands)

^c UTRECHT UNIVERSITY   (Netherlands)

^d VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^e NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^f LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Endophenotype; fMRI; frontoparietal; n back; obsessive compulsive disorder; working memory

Indexed keywords

ADULT; AGED; AMYGDALOID NUCLEUS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENDOPHENOTYPE; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; LIMBIC CORTEX; MALE; OBSESSIVE COMPULSIVE DISORDER; PARIETAL CORTEX; PRECUNEUS; SIBLING; TASK PERFORMANCE; WORKING MEMORY; ADOLESCENT; BRAIN MAPPING; FRONTAL LOBE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PARIETAL LOBE; PATHOPHYSIOLOGY; PHYSIOLOGY; SHORT TERM MEMORY; SPATIAL MEMORY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BRAIN MAPPING; ENDOPHENOTYPES; FEMALE; FRONTAL LOBE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMORY, SHORT-TERM; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PARIETAL LOBE; SIBLINGS; SPATIAL MEMORY; YOUNG ADULT;

EID: 84911458090     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.11.021     Document Type: Article

References (69)

1. G. Nestadt, J. Samuels, M. Riddle, O.J. Bienvenu III, K.Y. Liang, and M. LaBuda A family study of obsessive-compulsive disorder Arch Gen Psychiatry 57 2000 358 363
2. D.S. van Grootheest, D.C. Cath, A.T. Beekman, and D.I. Boomsma Twin studies on obsessive-compulsive disorder: A review Twin Res Hum Genet 8 2005 450 458
3. D.S. van Grootheest, M. Bartels, C.E. van Beijsterveldt, D.C. Cath, A.T. Beekman, J.J. Hudziak, and D.I. Boomsma Genetic and environmental contributions to self-report obsessive-compulsive symptoms in Dutch adolescents at ages 12, 14, and 16 J Am Acad Child Adolesc Psychiatry 47 2008 1182 1188
4. L. Menzies, S.R. Chamberlain, A.R. Laird, S.M. Thelen, B.J. Sahakian, and E.T. Bullmore Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: The orbitofronto-striatal model revisited Neurosci Biobehav Rev 32 2008 525 549
5. M. Melloni, C. Urbistondo, L. Sedeno, C. Gelormini, R. Kichic, and A. Ibanez The extended fronto-striatal model of obsessive compulsive disorder: Convergence from event-related potentials, neuropsychology and neuroimaging Front Hum Neurosci 6 2012 259
6. Gottesman II, and T.D. Gould The endophenotype concept in psychiatry: Etymology and strategic intentions Am J Psychiatry 160 2003 636 645
7. S.R. Chamberlain, and L. Menzies Endophenotypes of obsessive-compulsive disorder: Rationale, evidence and future potential Expert Rev Neurother 9 2009 1133 1146
8. S.R. Chamberlain, N.A. Fineberg, L.A. Menzies, A.D. Blackwell, E.T. Bullmore, T.W. Robbins, and B.J. Sahakian Impaired cognitive flexibility and motor inhibition in unaffected first-degree relatives of patients with obsessive-compulsive disorder Am J Psychiatry 164 2007 335 338
9. S.J. de Wit, F.E. de Vries, Y.D. van der Werf, D.C. Cath, D.J. Heslenfeld, and E.M. Veltman Presupplementary motor area hyperactivity during response inhibition: A candidate endophenotype of obsessive-compulsive disorder Am J Psychiatry 169 2012 1100 1108
10. G. Rajender, M.S. Bhatia, K. Kanwal, S. Malhotra, T.B. Singh, and D. Chaudhary Study of neurocognitive endophenotypes in drug-naive obsessive-compulsive disorder patients, their first-degree relatives and healthy controls Acta Psychiatr Scand 124 2011 152 161
11. P. Cavedini, C. Zorzi, M. Piccinni, M.C. Cavallini, and L. Bellodi Executive dysfunctions in obsessive-compulsive patients and unaffected relatives: Searching for a new intermediate phenotype Biol Psychiatry 67 2010 1178 1184
12. R. Delorme, V. Gousse, I. Roy, A. Trandafir, F. Mathieu, and M.C. Mouren-Simeoni Shared executive dysfunctions in unaffected relatives of patients with autism and obsessive-compulsive disorder Eur Psychiatry 22 2007 32 38
13. P.L. Remijnse, O.A. van den Heuvel, and D.J. Veltman Neuroimaging in obsessive-compulsive disorder Curr Med Imag Rev 1 2005 331 351
14. O.A. van den Heuvel, D.J. Veltman, H.J. Groenewegen, D.C. Cath, A.J. van Balkom, and J. van Hartskamp Frontal-striatal dysfunction during planning in obsessive-compulsive disorder Arch Gen Psychiatry 62 2005 301 309
15. B.M. Gu, J.Y. Park, D.H. Kang, S.J. Lee, S.Y. Yoo, and H.J. Jo Neural correlates of cognitive inflexibility during task-switching in obsessive-compulsive disorder Brain 131 2008 155 164
16. M. Yucel, B.J. Harrison, S.J. Wood, A. Fornito, R.M. Wellard, and J. Pujol Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder Arch Gen Psychiatry 64 2007 946 955
17. K.D. Fitzgerald, R.C. Welsh, W.J. Gehring, J.L. Abelson, J.A. Himle, I. Liberzon, and S.F. Taylor Error-related hyperactivity of the anterior cingulate cortex in obsessive-compulsive disorder Biol Psychiatry 57 2005 287 294
18. O.M. Kocak, A.Y. Ozpolat, C. Atbasoglu, and M. Cicek Cognitive control of a simple mental image in patients with obsessive-compulsive disorder Brain Cogn 76 2011 390 399
19. L. Menzies, G.B. Williams, S.R. Chamberlain, C. Ooi, N. Fineberg, and J. Suckling White matter abnormalities in patients with obsessive-compulsive disorder and their first-degree relatives Am J Psychiatry 165 2008 1308 1315
20. L. Menzies, S. Achard, S.R. Chamberlain, N. Fineberg, C.H. Chen, and N. del Campo Neurocognitive endophenotypes of obsessive-compulsive disorder Brain 130 2007 3223 3236
21. S.R. Chamberlain, L. Menzies, A. Hampshire, J. Suckling, N.A. Fineberg, and N. del Campo Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives Science 321 2008 421 422
22. A.M. Owen, K.M. McMillan, A.R. Laird, and E. Bullmore N-back working memory paradigm: A meta-analysis of normative functional neuroimaging studies Hum Brain Mapp 25 2005 46 59
23. R. Purcell, P. Maruff, M. Kyrios, and C. Pantelis Cognitive deficits in obsessive-compulsive disorder on tests of frontal-striatal function Biol Psychiatry 43 1998 348 357
24. N.J. van der Wee, N.F. Ramsey, J.M. Jansma, D.A. Denys, H.J. van Megen, H.M. Westenberg, and R.S. Kahn Spatial working memory deficits in obsessive compulsive disorder are associated with excessive engagement of the medial frontal cortex Neuroimage 20 2003 2271 2280
25. C.R. Savage, L. Baer, N.J. Keuthen, H.D. Brown, S.L. Rauch, and M.A. Jenike Organizational strategies mediate nonverbal memory impairment in obsessive-compulsive disorder Biol Psychiatry 45 1999 905 916
26. Y.W. Shin, J.S. Kwon, J.J. Kim, D.H. Kang, T. Youn, and K.W. Kang Altered neural circuit for working memory before and after symptom provocation in patients with obsessive-compulsive disorder Acta Psychiatr Scand 113 2006 420 429
27. K. Koch, G. Wagner, C. Schachtzabel, G. Peikert, C.C. Schultz, H. Sauer, and R.G. Schlösser Aberrant anterior cingulate activation in obsessive-compulsive disorder is related to task complexity Neuropsychologia 50 2012 958 964
28. T. Nakao, A. Nakagawa, E. Nakatani, M. Nabeyama, H. Sanematsu, and T. Yoshiura Working memory dysfunction in obsessive-compulsive disorder: A neuropsychological and functional MRI study J Psychiatr Res 43 2009 784 791
29. I. Henseler, O. Gruber, S. Kraft, C. Krick, W. Reith, and P. Falkai Compensatory hyperactivations as markers of latent working memory dysfunctions in patients with obsessive-compulsive disorder: An fMRI study J Psychiatry Neurosci 33 2008 209 215
30. A.K. Kuelz, F. Hohagen, and U. Voderholzer Neuropsychological performance in obsessive-compulsive disorder: A critical review Biol Psychol 65 2004 185 236
31. B. Harkin, and K. Kessler The role of working memory in compulsive checking and OCD: A systematic classification of 58 experimental findings Clin Psychol Rev 31 2011 1004 1021
32. O.A. van den Heuvel, D. Mataix-Cols, G. Zwitser, D.C. Cath, Y.D. van der Werf, and H.J. Groenewegen Common limbic and frontal-striatal disturbances in patients with obsessive compulsive disorder, panic disorder and hypochondriasis Psychol Med 41 2011 2399 2410
33. D.H. Kang, J.H. Jang, J.Y. Han, J.H. Kim, W.H. Jung, and J.S. Choi Neural correlates of altered response inhibition and dysfunctional connectivity at rest in obsessive-compulsive disorder Prog Neuropsychopharmacol Biol Psychiatry 40 2013 340 346
34. J. Schuurmans, A.J. van Balkom, H.J. van Megen, J.H. Smit, M. Eikelenboom, and D.C. Cath The Netherlands Obsessive Compulsive Disorder Association (NOCDA) study: Design and rationale of a longitudinal naturalistic study of the course of OCD and clinical characteristics of the sample at baseline Int J Methods Psychiatr Res 21 2012 273 285
35. M.B. First, R.L. Spitzer, M. Gibbon, and J.B. Williams Structured Clinical Interview for DSM-IV Axis I Disorders - Patient Edition (SCID-I/P, Version 2.0) 1996 New York State Psychiatric Institute, Biometrics Research Department New York
36. E.B. Foa, J.D. Huppert, S. Leiberg, R. Langner, R. Kichic, G. Hajcak, and P.M. Salkovskis The Obsessive-Compulsive Inventory: Development and validation of a short version Psychol Assess 14 2002 485 496
37. W.K. Goodman, L.H. Price, S.A. Rasmussen, C. Mazure, P. Delgado, G.R. Heninger, and D.S. Charney The Yale-Brown Obsessive Compulsive Scale. II. Validity Arch Gen Psychiatry 46 1989 1012 1016
38. S.A. Montgomery, and M. Asberg A new depression scale designed to be sensitive to change Br J Psychiatry 134 1979 382 389
39. A.T. Beck, N. Epstein, G. Brown, and R.A. Steer An inventory for measuring clinical anxiety: Psychometric properties J Consult Clin Psychol 56 1988 893 897
40. R.C. Oldfield The assessment and analysis of handedness: The Edinburgh Inventory Neuropsychologia 9 1971 97 113
41. B. Schmand, D. Bakker, R. Saan, and J. Louman [The Dutch Reading Test for Adults: A measure of premorbid intelligence level] Tijdschr Gerontol Geriatr 22 1991 15 19
42. H.E. Nelson The National Adult Reading Test (NART): Test Manual 1982 NFER-NELSON Publishing Company, Ltd Windsor, UK
43. A. Gevins, and B. Cutillo Spatiotemporal dynamics of component processes in human working memory Electroencephalogr Clin Neurophysiol 87 1993 128 143
44. M. Brett, J. Anton, R. Valabregue, and J.B. Poline Region of interest analysis using an SPM toolbox Neuroimage 16 2002 2
45. K.J. Worsley, S. Marrett, P. Neelin, A.C. Vandal, K.J. Friston, and A.C. Evans A unified statistical approach for determining significant signals in images of cerebral activation Hum Brain Mapp 4 1996 58 73
46. J.H. Callicott, A. Bertolino, V.S. Mattay, F.J. Langheim, J. Duyn, and R. Coppola Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited Cereb Cortex 10 2000 1078 1092
47. Z.N. Mannie, C.J. Harmer, P.J. Cowen, and R. Norbury A functional magnetic resonance imaging study of verbal working memory in young people at increased familial risk of depression Biol Psychiatry 67 2010 471 477
48. D.G. McLaren, M.L. Ries, G. Xu, and S.C. Johnson A generalized form of context-dependent psychophysiological interactions (gPPI): A comparison to standard approaches Neuroimage 61 2012 1277 1286
49. O.A. van den Heuvel, P.L. Remijnse, D. Mataix-Cols, H. Vrenken, H.J. Groenewegen, and H.B. Uylings The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems Brain 132 2009 853 868
50. J. Pujol, C. Soriano-Mas, P. Alonso, N. Cardoner, J.M. Menchon, J. Deus, and J. Vallejo Mapping structural brain alterations in obsessive-compulsive disorder Arch Gen Psychiatry 61 2004 720 730
51. N.J. Schneider-Garces, B.A. Gordon, C.R. Brumback-Peltz, E. Shin, Y. Lee, and B.P. Sutton Span, CRUNCH, and beyond: Working memory capacity and the aging brain J Cogn Neurosci 22 2010 655 669
52. M. D'Esposito, B.R. Postle, and B. Rypma Prefrontal cortical contributions to working memory: Evidence from event-related fMRI studies Exp Brain Res 133 2000 3 11
53. J.M. Jansma, N.F. Ramsey, R. Coppola, and R.S. Kahn Specific versus nonspecific brain activity in a parametric N-back task Neuroimage 12 2000 688 697
54. P.A. Reuter-Lorenz, and K.A. Cappell Neurocognitive aging and the compensation hypothesis Curr Dir Psychol Sci 17 2008 177 182
55. S. Moritz, M. Kloss, H. Jahn, M. Schick, and I. Hand Impact of comorbid depressive symptoms on nonverbal memory and visuospatial performance in obsessive-compulsive disorder Cogn Neuropsychiatry 8 2003 261 272
56. T. Johnstone, C.M. Van Reekum, H.L. Urry, N.H. Kalin, and R.J. Davidson Failure to regulate: Counterproductive recruitment of top-down prefrontal-subcortical circuitry in major depression J Neurosci 27 2007 8877 8884
57. E.R. Stern, R.C. Welsh, R. Gonzalez, K.D. Fitzgerald, J.L. Abelson, and S.F. Taylor Subjective uncertainty and limbic hyperactivation in obsessive-compulsive disorder Hum Brain Mapp 34 2013 1956 1970
58. P.R. Goldin, T. Manber-Ball, K. Werner, R. Heimberg, and J.J. Gross Neural mechanisms of cognitive reappraisal of negative self-beliefs in social anxiety disorder Biol Psychiatry 66 2009 1091 1099
59. A. den Braber, D. van 't Ent, D.C. Cath, J. Wagner, D.I. Boomsma, and E.J. de Geus Brain activation during cognitive planning in twins discordant or concordant for obsessive-compulsive symptoms Brain 133 2010 3123 3140
60. P.R. Szeszko, B.A. Ardekani, M. Ashtari, A.K. Malhotra, D.G. Robinson, R.M. Bilder, and K.O. Lim White matter abnormalities in obsessive-compulsive disorder: A diffusion tensor imaging study Arch Gen Psychiatry 62 2005 782 790
61. R.F. Salazar, N.M. Dotson, S.L. Bressler, and C.M. Gray Content-specific fronto-parietal synchronization during visual working memory Science 338 2012 1097 1100
62. E.R. Stern, K.D. Fitzgerald, R.C. Welsh, J.L. Abelson, and S.F. Taylor Resting-state functional connectivity between fronto-parietal and default mode networks in obsessive-compulsive disorder PLoS One 7 2012 e36356
63. A. Gazzaley, J.W. Cooney, J. Rissman, and M. D'Esposito Top-down suppression deficit underlies working memory impairment in normal aging Nat Neurosci 8 2005 1298 1300
64. K.T. Ciesielski, S.L. Rauch, S.P. Ahlfors, M.E. Vangel, S. Wilhelm, B.R. Rosen, and M.S. Hämäläinen Role of medial cortical networks for anticipatory processing in obsessive-compulsive disorder Hum Brain Mapp 33 2012 2125 2134
65. D.E. Linden, I. Habes, S.J. Johnston, S. Linden, R. Tatineni, and L. Subramanian Real-time self-regulation of emotion networks in patients with depression PLoS One 7 2012 e38115
66. H. Klumpp, D.A. Fitzgerald, and K.L. Phan Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder Prog Neuropsychopharmacol Biol Psychiatry 45 2013 83 91
67. V. Paquette, J. Levesque, B. Mensour, J.M. Leroux, G. Beaudoin, P. Bourgouin, and M. Beauregard "Change the mind and you change the brain": Effects of cognitive-behavioral therapy on the neural correlates of spider phobia Neuroimage 18 2003 401 409
68. M.Q. Hoexter, E.C. Miguel, J.B. Diniz, R.G. Shavitt, G.F. Busatto, and J.R. Sato Predicting obsessive-compulsive disorder severity combining neuroimaging and machine learning methods J Affect Disord 150 2013 1213 1216
69. M. Weygandt, C.R. Blecker, A. Schafer, K. Hackmack, J.D. Haynes, and D. Vaitl fMRI pattern recognition in obsessive-compulsive disorder Neuroimage 60 2012 1186 1193