Several transport systems contribute to the intestinal uptake of Paraquat, modulating its cytotoxic effects

Toxicology Letters

Volumn 232, Issue 1, 2015, Pages 271-283

  Silva, Renata ^a   Carmo, Helena ^a   Vilas Boas, Vânia ^a   Barbosa, Daniel José ^a   Monteiro, Márcia ^a   de Pinho, Paula Guedes ^a   de Lourdes Bastos, Maria ^a   Remião, Fernando ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

Arginine; Choline; Lysine; Paraquat intestinal uptake; Putrescine; Y+ transport system

Indexed keywords

AMINO ACID; AMINO ACID TRANSPORTER; ARGININE; CHOLINE; LYSINE; N ETHYLMALEIMIDE; PARAQUAT; PUTRESCINE; TRIFLUOPERAZINE; VALINE; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; CARRIER PROTEIN; CHOLINE TRANSPORTER; HERBICIDE; MINOR HISTOCOMPATIBILITY ANTIGEN; SLC1A5 PROTEIN, HUMAN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; EC50; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; INTESTINE ABSORPTION; ION TRAP MASS SPECTROMETRY; CACO-2 CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; INFRARED SPECTROPHOTOMETRY; INTESTINE MUCOSA; KINETICS; MASS FRAGMENTOGRAPHY; METABOLISM; PATHOLOGY;

AMINO ACID TRANSPORT SYSTEM ASC; AMINO ACID TRANSPORT SYSTEM Y+; AMINO ACID TRANSPORT SYSTEM Y+L; CACO-2 CELLS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HERBICIDES; HUMANS; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; KINETICS; MEMBRANE TRANSPORT MODULATORS; MEMBRANE TRANSPORT PROTEINS; MINOR HISTOCOMPATIBILITY ANTIGENS; PARAQUAT; SPECTROPHOTOMETRY, INFRARED;

EID: 84911457479     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.10.015     Document Type: Article

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