Sphingomyelin phosphodiesterase acid-like 3A (SMPDL3A) is a novel nucleotide phosphodiesterase regulated by cholesterol in human macrophages

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32895-32913

  Traini, Mathew ^a   Quinn, Carmel M ^b   Sandoval, Cecilia ^b   Johansson, Erik ^a   Schroder, Kate ^c   Kockx, Maaike ^a   Meikle, Peter J ^d   Jessup, Wendy ^a   Kritharides, Leonard ^a,e  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF QUEENSLAND   (Australia)

^d BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^e Department of Microbiology and Infectious Diseases   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; ESTERS; GENE EXPRESSION; GENES; MACROPHAGES; METABOLISM; NUCLEOTIDES; PHOSPHOLIPIDS; PHYSIOLOGY; PROTEINS; TRANSCRIPTION;

ACID SPHINGOMYELINASE; ANTI-INFLAMMATORIES; ATHEROSCLEROTIC LESIONS; EXTRACELLULAR NUCLEOTIDES; INFLAMMATORY RESPONSE; INFLAMMATORY SIGNALING; PHOSPHODIESTERASE ACTIVITY; PROTEIN EXPRESSIONS;

CELL SIGNALING;

ADENOSINE TRIPHOSPHATE; CHOLESTEROL; CYCLIC AMP; LIVER X RECEPTOR; PHOSPHODIESTERASE; PROTEIN SMPDL3A; UNCLASSIFIED DRUG; NUCLEOTIDE; ORPHAN NUCLEAR RECEPTOR; SMPDL3A PROTEIN, HUMAN; SPHINGOMYELIN PHOSPHODIESTERASE; TRANSCRIPTOME;

ACIDITY; ARTICLE; ATHEROSCLEROSIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME GLYCOSYLATION; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME RELEASE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYDROLYSIS; MACROPHAGE; MOLECULAR PATHOLOGY; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SMPDL3A GENE; UPREGULATION; ANIMAL; BLOOD; CELL CULTURE; CHO CELL LINE; CONFOCAL MICROSCOPY; CRICETULUS; DNA MICROARRAY; DRUG EFFECTS; FOAM CELL; GENETICS; GOLGI COMPLEX; HAMSTER; HEK293 CELL LINE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CELL LINE, TUMOR; CELLS, CULTURED; CHO CELLS; CHOLESTEROL; CRICETINAE; CRICETULUS; CYCLIC AMP; FOAM CELLS; GOLGI APPARATUS; HEK293 CELLS; HUMANS; MACROPHAGES; MICROSCOPY, CONFOCAL; NUCLEOTIDES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORPHAN NUCLEAR RECEPTORS; PHOSPHORIC DIESTER HYDROLASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SPHINGOMYELIN PHOSPHODIESTERASE; TRANSCRIPTOME;

EID: 84911452843     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.612341     Document Type: Article

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