Pathogenesis of experimental Ebola virus infection in guinea pigs

Journal of Infectious Diseases

Volumn 179, Issue SUPPL. 1, 1999, Pages

  Connolly, Brett M ^a   Steele, Keith E ^a   Davis, Kelly J ^a   Geisbert, Thomas W ^a   Kell, Wayne M ^a   Jaax, Nancy K ^a   Jahrling, Peter B ^a,b  

^a U S ARMY   (United States)

^b USAM RIID   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; DATA ANALYSIS; EBOLA VIRUS; ELECTRON MICROSCOPY; FIBROBLAST; GUINEA PIG; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; PATHOGENESIS; PHAGOCYTE; PRIORITY JOURNAL; VIRUS INFECTION;

EID: 0032993240     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/514305     Document Type: Conference Paper

References (50)

1. 1. Martini GA. Marburg virus disease: clinical syndrome. In: Martini GA, Siegert R, eds. Marburg virus disease. New York City: Springer-Verlag, 1971:1-9.
2. 2. Murphy FA, Simpson DIH, Whitfield SG, Zlotnik I, Carter GB. Marburg virus infection in monkeys. Lab Invest 1971;24:279-91.
3. 3. Gear JSS, Casal GA, Gear AJ, et al. Outbreak of Marburg virus disease in Johannesburg. Br Med J 1975;4:489-93.
4. 4. Bowen ETW, Platt GS, Lloyd G, Baskerville A, Harris WJ, Vell EC. Viral haemorrhagic fever in southern Sudan and northern Zaire. Lancet 1977; 1:571-3.
5. 5. Baskerville A, Bowen ET, Platt GS, McArdell LB, Simpson DI. The pathology of experimental Ebola virus infection in monkeys. J Pathol 1978;125:131-8.
6. 6. World Health Organization. Ebola haemorrhagic fever in Zaire, 1976. Bull WHO 1978;56:271-93.
7. 7. World Health Organization. Ebola haemorrhagic fever in Sudan, 1976. Bull WHO 1978;56:247-70.
8. 8. Smith DH, Francis DP, Simpson DIH. African haemorrhagic fever in the Southern Sudan, 1976. The clinical manifestations. In: Pattyn SR, ed. Ebola virus hemorrhagic fever. Amsterdam: Elsevier/North Holland Biomedical Press, 1978:21-6.
9. 9. Dietrich M, Schumacher HH, Peters D, Knobloch J. Human pathology of Ebola virus infection in the Sudan. In: Pattyn SR, ed. Ebola virus hemorrhagic fever. New York City: Elsevier/North Holland Biomedical Press, 1978:37-42.
10. 10. Baskerville A, Fisher-Hoch SP, Neild GH, Dowsett AB. Ultrastructural pathology of experimental Ebola haemorrhagic fever virus infection. J Pathol 1985;147:199-209.
11. 11. Fisher-Hoch SP, Platt GS, Neild GH, et al. Pathophysiology of shock and hemorrhage in a fulminating viral infection (Ebola). J Infect Dis 1985; 152:887-94.
12. 12. McCormick JB, Bauer SP, Elliot LH, Webb PA, Johnson KM. Biologic differences between strains of Ebola virus from Zaire and Sudan. J Infect Dis 1983;149:264-7.
13. 13. Richman DD, Cleveland PH, McCormick JB, Johnson KM. Antigenic analysis of strains of Ebola virus: identification of two Ebola virus serotypes. J Infect Dis 1983;149:268-71.
14. 14. Cox NJ, McCormick JB, Johnson KM, Kiley MP. Evidence for two subtypes of Ebola virus based on oligonucleotide mapping of RNA. J Infect Dis 1983;149:272-5.
15. 15. Jahrling PB, Geisbert TW, Dalgard DW, et al. Preliminary report: isolation of Ebola virus from monkeys imported to USA. Lancet 1990;335: 502-5.
16. 16. World Health Organization. Ebola virus - update. Wkly Epidemiol Rec 1990;65:43.
17. 17. World Health Organization. Viral hemorrhagic fever in imported monkeys. Wkly Epidemiol Rec 1992;67:142-3.
18. 18. Hayes CG, Burans JP, Ksiazek TG. Outbreak of fatal illness among captive macaques in the Philippines caused by an Ebola-related filovirus. Am J Trop Med Hyg 1992;46:664-71.
19. 19. Centers for Disease Control and Prevention. Ebola-Reston virus infection among quarantined nonhuman primates - Texas, 1996;45:314-6.
20. 20. Centers for Disease Control and Prevention. Update: filovirus infections among persons with occupational exposure to nonhuman primates. MMWR 1990;39:266-7.
21. 21. Centers for Disease Control and Prevention. Update: filovirus infection in animal handlers. MMWR 1990;39:221.
22. 22. Le Guenno B, Formenty P, Wyers M, Gounon P, Walker F, Boesch C. Isolation and partial characterisation of a new strain of Ebola virus. Lancet 1995;345:1271-4.
23. 23. Centers for Disease Control and Prevention. Outbreak of Ebola viral hemorrhagic fever -Zaire, 1995. MMWR 1995;44:381-2.
24. 24. Centers for Disease Control and Prevention. Update: outbreak of Ebola viral hemorrhagic fever -Zaire, 1995. MMWR 1995;44:399.
25. 25. Choo V: Ebola fever outbreak confirmed in Gabon. Lancet 1996;347:528.
26. 26. World Health Organization. Outbreak of Ebola haemorrhagic fever in Gabon officially declared over. Wkly Epidemiol Rec 1996;71:125-6.
27. 27. Bowen ETW, Platt GS, Lloyd G, Raymond RT, Simpson DIH. A comparative study of strains of Ebola virus isolated from southern Sudan and northern Zaire in 1976. J Med Vir 1980;6:129-38.
28. 28. Pereboeva LA, Tkachev VK, Kolesnikova LV, Krendeleva L, Ryabchikova EI, Smolina MP. The ultrastructural changes in guinea pig organs during the serial passage of the Ebola virus. Vopr Virusol 1993;38: 179-82.
29. 29. Ryabchikova EI, Baranova SG, Tkachev VK, Grazhdantseva AA. The morphological changes in Ebola infection in guinea pigs. Vopr Virusol 1993;38:176-9.
30. 30. Ryabchikova E, Kolesnikova L. Smolina M, et al. Ebola virus infection in guinea pigs: presumable role of granulomatous inflammation in pathogenesis. Arch Virol 1996;141:909-21.
31. 31. Jahrling PB, Smith S, Hesse RA, Rhoderick JB. Pathogenesis of Lassa virus infection in guinea pigs. Infect Immun 1982;37:771-8.
32. 32. Kenyon RH, Condie RM, Jahrling PB, Peters CJ. Protection of guinea pigs against experimental Argentine hemorrhagic fever by purified human IgG: importance of elimination of infected cells. Microb Path 1990; 9:219-26.
33. 33. Hall WC, Geisbert TW, Huggins JW, Jahrling PB. Experimental infection of guinea pigs with Venezuelan hemorrhagic fever virus (Guanarito): a model of human disease. Am J Trop Med Hyg 1996;55:81-8.
34. 34. Jaax NK, Davis KJ, Geisbert TW, et al. Lethal experimental infection of rhesus monkeys with Ebola-Zaire (Mayinga) virus by the oral and conjunctival route of exposure. Arch Pathol Lab Med 1996;120: 140-55.
35. 35. Davis KJ, Anderson AO, Geisbert TW, et al. Pathology of experimental Ebola virus infection in African green monkeys. Involvement of fibroblastic reticular cells. 1997. Arch Path Lab Med 121:805-19.
36. 36. Connolly BM, Jenson AB, Peters CJ, Geyer SJ, Barth JF, McPherson RA. Pathogenesis of Pichinde virus in strain 13 guinea pigs: an immunocytochemical, virological and clinical chemistry study. Am J Trop Med Hyg 1993;49:10-24.
37. 3H-labelled nick translated cloned DNA probes. Biol Cell 1985;53:1-12.
38. 38. Pringle JH, Primrose L, Kind CN, Talbot IC, Lauder I. In situ hybridization demonstration of poly-adenylated RNA sequences in formalin-fixed paraffin sections using a biotinylated oligonucleotide poly d(T) probe. J Pathol 1989;158:279-86.
39. 39. Jahrling PB, Geisbert TW, Dalgard DW, et al. Preliminary report: isolation of Ebola virus from monkeys imported to USA. Lancet 1990;335: 502-5.
40. 40. Geisbert TW, Jahrling PR. Differentiation of filoviruses by electron microscopy. Virus Res 1995;39:129-50.
41. 41. Bowen ETW, Platt GS, Simpson DIH, McArdell LB, Raymond RT. Ebola haemorrhagic fever: experimental infection in monkeys. Trans Royal Soc Trop Med Hyg 1978;72:188-91.
42. 42. Johnson E, Jaax N, White J, Jahrling P. Lethal experimental infections of rhesus monkeys by aerosolized Ebola virus. Int J Exp Pathol 1995;76: 227-36.
43. 43. Sanchez A, Kiley MP, Holoway BP, Auperin DD. Sequence analysis of Ebola virus genome; organisation, genetic elements, and comparison with the genome of Marburg virus. Virus Res 1993;29:215-40.
44. 44. Sanchez A, Trappier SG, Mahy BWJ, Peters CJ, Nichal ST. The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing. Proc Natl Acad Sci USA 1996;93:3602-7.
45. 45. Yang Z, Delgado R, Xu I, Todd RF, Nabel EG, Sanchez A, Nabel GJ. Distinct cellular interactions of secreted and transmembrane Ebola virus glycoproteins. Science 1998;279:1034-7.
46. 46. Peters CJ, Sanchez A, Rollin PE, Ksiazek TG, Murphy FA. Filoviridae: Marburg and Ebola viruses. In: Fields BN, Knipe BM, Howley PM, eds. Fields virology. Philadelphia: Lippincott-Raven Publishers, 1996: 1191-76.
47. 47. Fisher-Hoch SP, Brammer TL, Trappier SG, et al. Pathogenic potential of filoviruses: role of geographic origin of primate host and virus strain. J Infect Dis 1992;166:753-63.
48. 48. Feldmann H, Bugany H, Mahner F, Klenk HD, Drenckhahn D, Schnittler HJ. Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages. J Virol 1996;70:2208-14.
49. 49. Clampitt RB, Hart RJ. The tissue activities of some diagnostic enzymes in ten mammalian species. J Comp Pathol 1978;88:607-21.
50. 50. Hoffmann WE, Kramer J, Main AR, Torres JL. Clinical enzymology. In: Loeb WF, Quimby FW. The clinical chemistry of laboratory animals. 1st ed. New York City: Pergamon Press, 1989:237-78.