Tolerogenic splenic IDO+ dendritic cells from the mice treated with induced-treg cells suppress collagen-induced arthritis

Journal of Immunology Research

Volumn 2014, Issue , 2014, Pages

  Yang, Jie ^a,b   Yang, Yiming ^b   Fan, Huahua ^b   Zou, Hejian ^a  

^a FUDAN UNIVERSITY   (China)

^b Shanghai Blood Center   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; INDOLEAMINE 2,3 DIOXYGENASE; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 17; INTERLEUKIN 6; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; CD11B ANTIGEN; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CD25+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DEATH; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; ENZYME RELEASE; EX VIVO STUDY; HISTOLOGY; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEROLOGY; SPLEEN CELL; TH17 CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; ARTHRITIS, EXPERIMENTAL; CELL PROLIFERATION; CYTOLOGY; DBA MOUSE; FLOW CYTOMETRY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; PROCEDURES; SPLEEN; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD11B; ARTHRITIS, EXPERIMENTAL; CELL PROLIFERATION; DENDRITIC CELLS; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; IMMUNE TOLERANCE; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INTERLEUKIN-10; MALE; MICE, INBRED DBA; SPLEEN; T-LYMPHOCYTES, REGULATORY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84911360463     PISSN: 23148861     EISSN: 23147156     Source Type: Journal    
DOI: 10.1155/2014/831054     Document Type: Article

References (30)

1. + regulatory T cells. Nature Reviews Immunology 2011 11 2 119 130 10.1038/nri2916 2-s2.0-79251500661
2. Kong N., Lan Q., Chen M., Wang J., Shi W., Horwitz D. A., Quesniaux V., Ryffel B., Liu Z., Brand D., Zou H., Zheng S. G., Antigen-specific transforming growth factor β -induced treg cells, but not natural treg cells, ameliorate autoimmune arthritis in mice by shifting the Th17/treg cell balance from Th17 predominance to treg cell predominance. Arthritis and Rheumatism 2012 64 8 2548 2558 10.1002/art.34513 2-s2.0-84864424816
3. + cells in the recipient. International Immunology 2006 18 2 279 289 10.1093/intimm/dxh368 2-s2.0-31544467631
4. Manicassamy S., Pulendran B., Dendritic cell control of tolerogenic responses. Immunological Reviews 2011 241 1 206 227 10.1111/j.1600-065X.2011.01015.x 2-s2.0-79954506102
5. Yang J., Li R., Ren Y., Yang Y., Xie R., Fan H., Third-party tolerogenic dendritic cells reduce allo-reactivity in vitro and ameliorate the severity of acute graft-versus-host disease in allo-bone marrow transplantation. Scandinavian Journal of Immunology 2013 78 6 486 496 10.1111/sji.12113 2-s2.0-84888410860
6. Yang J., Yang Y., Ren Y., Xie R., Zou H., Fan H., A Mouse model of adoptive immunotherapeutic targeting of autoimmune arthritis using allo-tolerogenic dendritic cells. PLoS ONE 2013 8 10 e77729 10.1371/journal.pone.0077729 2-s2.0-84886239367
7. H17 to regulatory T cells in HIV disease. Science Translational Medicine 2010 2 32 10.1126/scitranslmed.3000632 2-s2.0-77952977625
8. Qin S., Cobbold S. P., Pope H., Elliott J., Kioussis D., Davies J., Waldmann H., 'Infectious' transplantation tolerance. Science 1993 259 5097 974 977 10.1126/science.8094901 2-s2.0-0027479685
9. + Treg cells induce TGF β -dependent tolerogenic dendritic cells that suppress the Murine Lupus-Like Syndrome. Journal of Molecular Cell Biology 2012 4 6 409 419
10. Fallarino F., Grohmann U., Puccetti P., Indoleamine 2,3-dioxygenase: From catalyst to signaling function. European Journal of Immunology 2012 42 8 1932 1937 10.1002/eji.201242572 2-s2.0-84864776540
11. Cobbold S. P., Adams E., Farquhar C. A., Nolan K. F., Howie D., Lui K. O., Fairchild P. J., Mellor A. L., Ron D., Waldmann H., Infectious tolerance via the consumption of essential amino acids and mTOR signaling. Proceedings of the National Academy of Sciences of the United States of America 2009 106 29 12055 12060 10.1073/pnas.0903919106 2-s2.0-67749091321
12. Fantini M. C., Dominitzki S., Rizzo A., Neurath M. F., Becker C., In vitro generation of CD4+ CD25+ regulatory cells from murine naive T cells. Nature Protocols 2007 2 7 1789 1794 10.1038/nprot.2007.258 2-s2.0-34548564632
13. + dendritic cells from orally tolerized mice is responsible for induction of systemic immune tolerance and suppression of collagen-induced arthritis. Cellular Immunology 2012 278 1-2 45 54 10.1016/j.cellimm.2012.06.009 2-s2.0-84868281887
14. Bianco N. R., Kim S. H., Ruffner M. A., Robbins P. D., Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models. Arthritis & Rheumatism 2009 60 2 380 389 10.1002/art.24229 2-s2.0-59649083739
15. + regulatory T cells in the maintenance of immune tolerance. Frontiers in Immunology 2012 3 1 10 10.3389/fimmu.2012.00165 2-s2.0-84871402588
16. Criado G., Šimelyte E., Inglis J. J., Essex D., Williams R. O., Indoleamine 2,3 dioxygenase-mediated tryptophan catabolism regulates accumulation of Th1/Th17 cells in the joint in collagen-induced arthritis. Arthritis & Rheumatism 2009 60 5 1342 1351 10.1002/art.24446 2-s2.0-66049126424
17. Fontenot J. D., Rasmussen J. P., Williams L. M., Dooley J. L., Farr A. G., Rudensky A. Y., Regulatory T cell lineage specification by the forkhead transcription factor Foxp3. Immunity 2005 22 3 329 341 10.1016/j.immuni.2005.01.016 2-s2.0-15244354286
18. Wing K., Sakaguchi S., Regulatory T cells exert checks and balances on self tolerance and autoimmunity. Nature Immunology 2010 11 1 7 13 10.1038/ni.1818 2-s2.0-74049164847
19. Lan R. Y., Ansari A. A., Lian Z.-X., Gershwin M. E., Regulatory T cells: development, function and role in autoimmunity. Autoimmunity Reviews 2005 4 6 351 363 10.1016/j.autrev.2005.01.007 2-s2.0-23144450643
20. Zhou X., Kong N., Wang J., Fan H., Zou H., Horwitz D., Brand D., Liu Z., Zheng S. G., Cutting edge: All-trans retinoic acid sustains the stability and function of natural regulatory T cells in an inflammatory milieu. The Journal of Immunology 2010 185 5 2675 2679 10.4049/jimmunol.1000598 2-s2.0-78049373227
21. Huter E. N., Stummvoll G. H., DiPaolo R. J., Glass D. D., Shevach E. M., Cutting edge: antigen-specific TGF β -induced regulatory T cells suppress Th17-mediated autoimmune disease. The Journal of Immunology 2008 181 12 8209 8213 10.4049/jimmunol.181.12.8209 2-s2.0-58849112222
22. Zheng S. G., Wang J. H., Koss M. N., Quismorio F. Jr., Gray J. D., Horwitz D. A., CD4+ and CD8+ regulatory T cells generated ex vivo with IL-2 and TGF-beta suppress a stimulatory graft-versus-host disease with a lupus-like syndrome. Journal of Immunology 2004 172 3 1531 1539 10.4049/jimmunol.172.3.1531 2-s2.0-1242267910
23. Godebu E., Summers-Torres D., Lin M. M., Baaten B. J. G., Bradley L. M., Polyclonal adaptive regulatory CD4 cells that can reverse type I diabetes become oligoclonal long-term protective memory cells. Journal of Immunology 2008 181 3 1798 1805 10.4049/jimmunol.181.3.1798 2-s2.0-49649095420
24. + regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model. Arthritis Research & Therapy 2008 10 1, article R11 10.1186/ar2361 2-s2.0-39549096220
25. Saas P., Perruche S., Functions of TGF- β -exposed plasmacytoid dendritic cells. Critical Reviews in Immunology 2012 32 6 529 553 10.1615/CritRevImmunol.2013005868 2-s2.0-84873738307
26. Iwasaki A., Kelsall B. L., Freshly isolated peyer's patch, but not spleen, dendritic cells produce interleukin 10 and induce the differentiation of T helper type 2 cells. The Journal of Experimental Medicine 1999 190 2 229 240 10.1084/jem.190.2.229 2-s2.0-0033584234
27. Adikari S. B., Lian H., Link H., Huang Y.-M., Xiao B.-G., Interferon- γ -modified dendritic cells suppress B cell function and ameliorate the development of experimental autoimmune myasthenia gravis. Clinical & Experimental Immunology 2004 138 2 230 236 10.1111/j.1365-2249.2004.02585.x 2-s2.0-8144224918
28. + dendritic cells. European Journal of Immunology 2007 37 4 1064 1071 10.1002/eji.200636690 2-s2.0-34249710405
29. Dürr S., Kindler V., Implication of indolamine 2,3 dioxygenase in the tolerance toward fetuses, tumors, and allografts. Journal of Leukocyte Biology 2013 93 5 681 687 10.1189/jlb.0712347 2-s2.0-84877082935
30. Kwidzinski E., Bechmann I., IDO expression in the brain: a double-edged sword. Journal of Molecular Medicine 2007 85 12 1351 1359 10.1007/s00109-007-0229-7 2-s2.0-36849077601