The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation

Developmental Biology

Volumn 394, Issue 1, 2014, Pages 39-53

  Mulherkar, Shalaka ^a   Uddin, Mohammad Danish ^b   Couvillon, Anthony D ^c,e   Sillitoe, Roy V ^a,d   Tolias, Kimberley F ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF HOUSTON   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d TEXAS CHILDREN S HOSPITAL   (United States)

^e CELL SIGNALING TECHNOLOGY   (United States)

Author keywords

Bergmann glia; Cell shape changes; Foliation; Granule cell precursors; Granule cells; Rho GTPases

Indexed keywords

RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; ABR PROTEIN, MOUSE; ANTIESTROGEN; BCR PROTEIN, MOUSE; BREAKPOINT CLUSTER REGION PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NEUROPEPTIDE; RAC1 PROTEIN, MOUSE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, MOUSE; TAMOXIFEN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; BRAIN DEVELOPMENT; CELL MIGRATION; CELL SHAPE; CEREBELLUM; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE DELETION; GRANULE CELL; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; SIGNAL TRANSDUCTION; ANIMAL; BERGMANN GLIA LAYER; BIOSYNTHESIS; C57BL MOUSE; CELL MOTION; CELL SHAPE CHANGES; FOLIATION; GENETICS; GLIA; GRANULE CELL PRECURSORS; GRANULE CELLS; KNOCKOUT MOUSE; MORPHOGENESIS; PHYSIOLOGY; PRENATAL DEVELOPMENT; RHO GTPASES;

MUS;

BERGMANN GLIA; CELL SHAPE CHANGES; FOLIATION; GRANULE CELL PRECURSORS; GRANULE CELLS; RHO GTPASES;

ANIMALS; BASEMENT MEMBRANE; BODY PATTERNING; CELL MOVEMENT; CEREBELLUM; ESTROGEN ANTAGONISTS; GTPASE-ACTIVATING PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHOGENESIS; NEUROGLIA; NEUROPEPTIDES; PROTO-ONCOGENE PROTEINS C-BCR; RAC1 GTP-BINDING PROTEIN; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; TAMOXIFEN;

EID: 84911005769     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2014.08.004     Document Type: Article

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