Mode of Action of S-Methyl-N, N-Diethylthiocarbamate Sulfoxide (DETC-MeSO) as a Novel Therapy for Stroke in a Rat Model

Molecular Neurobiology

Volumn 50, Issue 2, 2014, Pages 655-672

  Mohammad Gharibani, Payam ^a   Modi, Jigar ^a,b   Menzie, Janet ^a   Genova, Rafaella ^a   Ma, Zhiyuan ^a   Tao, Rui ^a,b   Prentice, Howard ^a,b   Wu, Jang Yen ^a,b,c  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b FLORIDA ATLANTIC UNIVERSITY   (United States)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

DETC MeSO; Endoplasmic reticulum stress; Excitotoxicity; Neuroprotection; Primary cortical neuronal culture; Stroke

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ALPHA2 SPECTRIN; DOPAMINE; FODRIN; GLUTAMATE RECEPTOR ANTAGONIST; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; HEAT SHOCK PROTEIN 27; INITIATION FACTOR 2ALPHA; METHYL N,N DIETHYLTHIOCARBAMATE SULFOXIDE; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPROTECTIVE AGENT; POTASSIUM; STRESS ACTIVATED PROTEIN KINASE; SULFOXIDE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; GLUTAMATE RECEPTOR; S-METHYL-N,N-DIETHYLDITHIOCARBAMOYL SULFOXIDE;

ADULT; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL CULTURE; BRAIN INFARCTION SIZE; CELL HYPOXIA; CELL PROTECTION; CELL SURVIVAL; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE MODEL; DOPAMINE RELEASE; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; EXCITOTOXICITY; FETUS; GLIOSIS; IMMUNOBLOTTING; IN VITRO STUDY; MALE; MICRODIALYSIS; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NEUROSCORE TEST; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIMARY CELL CULTURE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; RAT MODEL; REDUCTION; REOXYGENATION; REPERFUSION; TASK PERFORMANCE; ANIMAL; BRAIN; CELL CULTURE; CELL DEATH; DRUG EFFECTS; FEMALE; NERVE CELL; STROKE;

ANIMALS; APOPTOSIS; BRAIN; CELL DEATH; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RECEPTORS, GLUTAMATE; STROKE; SULFOXIDES;

EID: 84911005681     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8658-0     Document Type: Article

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