-
1
-
-
68549104124
-
Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases
-
Dong JT, Chen C. Essential role of KLF5 transcription factor in cell proliferation and differentiation and its implications for human diseases. Cell Mol Life Sci 2009;66:2691-706.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2691-2706
-
-
Dong, J.T.1
Chen, C.2
-
2
-
-
1842425769
-
Intestinal tumor progression is associated with altered function of KLF5
-
Bateman NW, Tan D, Pestell RG, et al. Intestinal tumor progression is associated with altered function of KLF5. J Biol Chem 2004;279:12093-101.
-
(2004)
J Biol Chem
, vol.279
, pp. 12093-12101
-
-
Bateman, N.W.1
Tan, D.2
Pestell, R.G.3
-
3
-
-
0037179848
-
A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer
-
Chen C, Bhalala HV, Qiao H, et al. A possible tumor suppressor role of the KLF5 transcription factor in human breast cancer. Oncogene 2002;21: 6567-72.
-
(2002)
Oncogene
, vol.21
, pp. 6567-6572
-
-
Chen, C.1
Bhalala, H.V.2
Qiao, H.3
-
4
-
-
0037405689
-
KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer
-
Chen C, Bhalala HV, Vessella RL, et al. KLF5 is frequently deleted and down-regulated but rarely mutated in prostate cancer. Prostate 2003;55: 81-8.
-
(2003)
Prostate
, vol.55
, pp. 81-88
-
-
Chen, C.1
Bhalala, H.V.2
Vessella, R.L.3
-
5
-
-
37349016202
-
Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
-
Nandan MO, McConnell BB, Ghaleb AM, et al. Kruppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis. Gastroenterology 2008;134: 120-30.
-
(2008)
Gastroenterology
, vol.134
, pp. 120-130
-
-
Nandan, M.O.1
McConnell, B.B.2
Ghaleb, A.M.3
-
6
-
-
33749423046
-
Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis
-
Sur I, Rozell B, Jaks V, et al. Epidermal and craniofacial defects in mice overexpressing Klf5 in the basal layer of the epidermis. J Cell Sci 2006; 119:3593-601.
-
(2006)
J Cell Sci
, vol.119
, pp. 3593-3601
-
-
Sur, I.1
Rozell, B.2
Jaks, V.3
-
7
-
-
0035985280
-
Human Kruppellike factor5/KLF5: Synergy with NF-kappaB/Rel factors and expression in human skin and hair follicles
-
Sur I, Unden AB, Toftgard R. Human Kruppellike factor5/KLF5: synergy with NF-kappaB/Rel factors and expression in human skin and hair follicles. Eur J Cell Biol 2002;81:323-34.
-
(2002)
Eur J Cell Biol
, vol.81
, pp. 323-334
-
-
Sur, I.1
Unden, A.B.2
Toftgard, R.3
-
8
-
-
79954557105
-
Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERbeta and KLF5
-
Nakajima Y, Akaogi K, Suzuki T, et al. Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERbeta and KLF5. Sci Signal 2011;4: ra22.
-
(2011)
Sci Signal
, vol.4
, pp. ra22
-
-
Nakajima, Y.1
Akaogi, K.2
Suzuki, T.3
-
9
-
-
33644559042
-
KLF5 promotes cell proliferation and tumorigenesis through gene regulation in the TSU-Pr1 human bladder cancer cell line
-
Chen C, Benjamin MS, Sun X, et al. KLF5 promotes cell proliferation and tumorigenesis through gene regulation in the TSU-Pr1 human bladder cancer cell line. Int J Cancer 2006;118: 1346-55.
-
(2006)
Int J Cancer
, vol.118
, pp. 1346-1355
-
-
Chen, C.1
Benjamin, M.S.2
Sun, X.3
-
10
-
-
70350575752
-
Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1
-
Zheng HQ, Zhou Z, Huang J, et al. Kruppel-like factor 5 promotes breast cell proliferation partially through upregulating the transcription of fibroblast growth factor binding protein 1. Oncogene 2009;28:3702-13.
-
(2009)
Oncogene
, vol.28
, pp. 3702-3713
-
-
Zheng, H.Q.1
Zhou, Z.2
Huang, J.3
-
11
-
-
66249142717
-
Haploinsufficiency of Kruppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine
-
McConnell BB, Bialkowska AB, Nandan MO, et al. Haploinsufficiency of Kruppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine. Cancer Res 2009;69:4125-33.
-
(2009)
Cancer Res
, vol.69
, pp. 4125-4133
-
-
McConnell, B.B.1
Bialkowska, A.B.2
Nandan, M.O.3
-
12
-
-
77952246162
-
Kruppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations
-
Nandan MO, Ghaleb AM, McConnell BB, et al. Kruppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations. Mol Cancer 2010;9:63.
-
(2010)
Mol Cancer
, vol.9
, pp. 63
-
-
Nandan, M.O.1
Ghaleb, A.M.2
McConnell, B.B.3
-
13
-
-
67650555438
-
Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells
-
Guo P, Zhao KW, Dong XY, et al. Acetylation of KLF5 alters the assembly of p15 transcription factors in transforming growth factor-beta-mediated induction in epithelial cells. J Biol Chem 2009; 284:18184-93.
-
(2009)
J Biol Chem
, vol.284
, pp. 18184-18193
-
-
Guo, P.1
Zhao, K.W.2
Dong, X.Y.3
-
14
-
-
70350502092
-
Opposing effects of KLF5 on the transcription of MYC in epithelial proliferation in the context of transforming growth factor beta
-
Guo P, Dong XY, Zhao KW, et al. Opposing effects of KLF5 on the transcription of MYC in epithelial proliferation in the context of transforming growth factor beta. J Biol Chem 2009; 284:28243-52.
-
(2009)
J Biol Chem
, vol.284
, pp. 28243-28252
-
-
Guo, P.1
Dong, X.Y.2
Zhao, K.W.3
-
15
-
-
65249114297
-
Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification
-
Guo P, Dong XY, Zhang X, et al. Pro-proliferative factor KLF5 becomes anti-proliferative in epithelial homeostasis upon signaling-mediated modification. J Biol Chem 2009;284:6071-8.
-
(2009)
J Biol Chem
, vol.284
, pp. 6071-6078
-
-
Guo, P.1
Dong, X.Y.2
Zhang, X.3
-
16
-
-
78649903609
-
Overexpression of transforming growth factor beta1 in malignant prostate cells is partly caused by a runaway of TGF-beta1 auto-induction mediated through a defective recruitment of protein phos-phatase 2A by TGF-beta type i receptor
-
Yu N, Kozlowski JM, Park, II, et al. Overexpression of transforming growth factor beta1 in malignant prostate cells is partly caused by a runaway of TGF-beta1 auto-induction mediated through a defective recruitment of protein phos-phatase 2A by TGF-beta type I receptor. Urology 2010;76:1519.e8-e13.
-
(2010)
Urology
, vol.76
, pp. 1519e8-e13
-
-
Yu, N.1
Kozlowski, J.M.2
Park, I.I.3
-
17
-
-
0026080110
-
Effects of interferon beta ser and transforming growth factor beta on prostatic cell lines
-
Goldstein D, O'Leary M, Mitchen J, et al. Effects of interferon beta ser and transforming growth factor beta on prostatic cell lines. J Urol 1991;146: 1173-7.
-
(1991)
J Urol
, vol.146
, pp. 1173-1177
-
-
Goldstein, D.1
O'leary, M.2
Mitchen, J.3
-
18
-
-
18844429239
-
Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells
-
Chen C, Sun X, Ran Q, et al. Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells. Oncogene 2005;24:3319-27.
-
(2005)
Oncogene
, vol.24
, pp. 3319-3327
-
-
Chen, C.1
Sun, X.2
Ran, Q.3
-
19
-
-
65449136284
-
TopHat: Discovering splice junctions with RNA-Seq
-
Trapnell C, Pachter L, Salzberg SL. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 2009;25:1105-11.
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
20
-
-
84859885816
-
Differential gene and transcript expression analysis of rnaseq experiments with tophat and cufflinks
-
Trapnell C, Roberts A, Goff L, et al. Differential gene and transcript expression analysis of RNAseq experiments with TopHat and Cufflinks. Nat Protoc 2012;7:562-78.
-
(2012)
Nat Protoc
, vol.7
, pp. 562-578
-
-
Trapnell, C.1
Roberts, A.2
Goff, L.3
-
21
-
-
77958471357
-
Differential expression analysis for sequence count data
-
Anders S, Huber W. Differential expression analysis for sequence count data. Genome Biol 2010; 11:R106.
-
(2010)
Genome Biol
, vol.11
, pp. R106
-
-
Anders, S.1
Huber, W.2
-
22
-
-
84874271270
-
NCBI GEO: Archive for functional genomics data sets-update
-
Barrett T, Wilhite SE, Ledoux P, et al. NCBI GEO: archive for functional genomics data sets-update. Nucleic Acids Res 2013;41:D991-5.
-
(2013)
Nucleic Acids Res
, vol.41
, pp. D991-D995
-
-
Barrett, T.1
Wilhite, S.E.2
Ledoux, P.3
-
23
-
-
0036081355
-
Gene expression omnibus: Ncbi gene expression and hybridization array data repository
-
Edgar R, Domrachev M, Lash AE. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 2002;30:207-10.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 207-210
-
-
Edgar, R.1
Domrachev, M.2
Lash, A.E.3
-
24
-
-
34447628843
-
Pathway mapping tools for analysis of high content data
-
Ekins S, Nikolsky Y, Bugrim A, et al. Pathway mapping tools for analysis of high content data. Methods Mol Biol 2007;356:319-50.
-
(2007)
Methods Mol Biol
, vol.356
, pp. 319-350
-
-
Ekins, S.1
Nikolsky, Y.2
Bugrim, A.3
-
25
-
-
13944271697
-
Antagonists of activin signaling: Mechanisms and potential biological applications
-
Harrison CA, Gray PC, Vale WW, et al. Antagonists of activin signaling: mechanisms and potential biological applications. Trends Endocrinol Metab 2005;16:73-8.
-
(2005)
Trends Endocrinol Metab
, vol.16
, pp. 73-78
-
-
Harrison, C.A.1
Gray, P.C.2
Vale, W.W.3
-
27
-
-
84878749367
-
Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells
-
Xing C, Fu X, Sun X, et al. Different expression patterns and functions of acetylated and unacetylated Klf5 in the proliferation and differentiation of prostatic epithelial cells. PLoS ONE 2013;8: e65538.
-
(2013)
PLoS ONE
, vol.8
, pp. e65538
-
-
Xing, C.1
Fu, X.2
Sun, X.3
-
28
-
-
79751473114
-
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44
-
Liu C, Kelnar K, Liu B, et al. The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. Nat Med 2011;17:211-5.
-
(2011)
Nat Med
, vol.17
, pp. 211-215
-
-
Liu, C.1
Kelnar, K.2
Liu, B.3
-
29
-
-
84863921583
-
MiRNA-708 control of CD44(+) prostate cancer-initiating cells
-
Saini S, Majid S, Shahryari V, et al. miRNA-708 control of CD44(+) prostate cancer-initiating cells. Cancer Res 2012;72:3618-30.
-
(2012)
Cancer Res
, vol.72
, pp. 3618-3630
-
-
Saini, S.1
Majid, S.2
Shahryari, V.3
-
30
-
-
33644871873
-
Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells
-
Chanchevalap S, Nandan MO, McConnell BB, et al. Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells. Nucleic Acids Res 2006;34:1216-23.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 1216-1223
-
-
Chanchevalap, S.1
Nandan, M.O.2
McConnell, B.B.3
-
31
-
-
9144274494
-
Regulation of platelet-derived growth factor-A chain by Kruppel-like factor 5: New pathway of cooperative activation with nuclear factor-kappaB
-
Aizawa K, Suzuki T, Kada N, et al. Regulation of platelet-derived growth factor-A chain by Kruppel-like factor 5: new pathway of cooperative activation with nuclear factor-kappaB. J Biol Chem 2004;279:70-6.
-
(2004)
J Biol Chem
, vol.279
, pp. 70-76
-
-
Aizawa, K.1
Suzuki, T.2
Kada, N.3
-
32
-
-
33744955883
-
KLF5 interacts with P53 in regulating survivin expression in acute lymphoblastic leukemia
-
Zhu N, Gu L, Findley HW, et al. KLF5 interacts with P53 in regulating survivin expression in acute lymphoblastic leukemia. J Biol Chem 2006; 281:14711-8.
-
(2006)
J Biol Chem
, vol.281
, pp. 14711-14718
-
-
Zhu, N.1
Gu, L.2
Findley, H.W.3
-
33
-
-
84883313474
-
Regulation of hypoxia-inducible factor 1alpha (HIF-1alpha) by lysophosphatidic acid is dependent on interplay between p53 and Kruppel-like factor 5
-
Lee SJ, No YR, Dang DT, et al. Regulation of hypoxia-inducible factor 1alpha (HIF-1alpha) by lysophosphatidic acid is dependent on interplay between p53 and Kruppel-like factor 5. J Biol Chem 2013;288:25244-53.
-
(2013)
J Biol Chem
, vol.288
, pp. 25244-25253
-
-
Lee, S.J.1
No, Y.R.2
Dang, D.T.3
-
34
-
-
80054015502
-
Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer
-
Yang Y, Nakagawa H, Tetreault MP, et al. Loss of transcription factor KLF5 in the context of p53 ablation drives invasive progression of human squamous cell cancer. Cancer Res 2011;
-
Cancer Res 2011
-
-
Yang, Y.1
Nakagawa, H.2
Tetreault, M.P.3
-
35
-
-
84869402788
-
P53 mutation alters the effect of the esophageal tumor suppressor KLF5 on keratinocyte proliferation
-
Yang Y, Tarapore RS, Jarmel MH, et al. p53 mutation alters the effect of the esophageal tumor suppressor KLF5 on keratinocyte proliferation. Cell Cycle 2012;11:4033-9.
-
(2012)
Cell Cycle
, vol.11
, pp. 4033-4039
-
-
Yang, Y.1
Tarapore, R.S.2
Jarmel, M.H.3
-
36
-
-
40249093059
-
A core Klf circuitry regulates self-renewal of embryonic stem cells
-
Jiang J, Chan YS, Loh YH, et al. A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat Cell Biol 2008;10:353-60.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 353-360
-
-
Jiang, J.1
Chan, Y.S.2
Loh, Y.H.3
-
37
-
-
74549152665
-
Kruppel-like factor (KLF) 5 mediates cyclin D1 expression and cell proliferation via interaction with c-Jun in Ang II-induced VSMCs
-
Liu Y, Wen JK, Dong LH, et al. Kruppel-like factor (KLF) 5 mediates cyclin D1 expression and cell proliferation via interaction with c-Jun in Ang II-induced VSMCs. Acta Pharmacol Sin 2010;31:10-8.
-
(2010)
Acta Pharmacol Sin
, vol.31
, pp. 10-18
-
-
Liu, Y.1
Wen, J.K.2
Dong, L.H.3
-
38
-
-
70449623252
-
Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cells
-
He M, Han M, Zheng B, et al. Angiotensin II stimulates KLF5 phosphorylation and its interaction with c-Jun leading to suppression of p21 expression in vascular smooth muscle cells. J Biochem 2009;146:683-91.
-
(2009)
J Biochem
, vol.146
, pp. 683-691
-
-
He, M.1
Han, M.2
Zheng, B.3
-
39
-
-
0035971506
-
Jun, the oncoprotein
-
Vogt PK. Jun, the oncoprotein. Oncogene 2001; 20:2365-77.
-
(2001)
Oncogene
, vol.20
, pp. 2365-2377
-
-
Vogt, P.K.1
-
40
-
-
73449090855
-
Estrogeninduced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells
-
Guo P, Dong XY, Zhao KW, et al. Estrogeninduced interaction between KLF5 and estrogen receptor (ER) suppresses the function of ER in ER-positive breast cancer cells. Int J Cancer 2010; 126:81-9.
-
(2010)
Int J Cancer
, vol.126
, pp. 81-89
-
-
Guo, P.1
Dong, X.Y.2
Zhao, K.W.3
-
41
-
-
69449096661
-
Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro
-
Frigo DE, Sherk AB, Wittmann BM, et al. Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. Mol Endocrinol 2009;23:1385-96.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1385-1396
-
-
Frigo, D.E.1
Sherk, A.B.2
Wittmann, B.M.3
-
42
-
-
1842839974
-
Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells
-
Chen C, Zhou Y, Zhou Z, et al. Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells. Gene 2004;330:133-42.
-
(2004)
Gene
, vol.330
, pp. 133-142
-
-
Chen, C.1
Zhou, Y.2
Zhou, Z.3
-
43
-
-
84893055415
-
KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelialmesenchymal transition in epithelial cells
-
Zhang B, Zhang Z, Xia S, et al. KLF5 activates microRNA 200 transcription to maintain epithelial characteristics and prevent induced epithelialmesenchymal transition in epithelial cells. Mol Cell Biol 2013;33:4919-35.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 4919-4935
-
-
Zhang, B.1
Zhang, Z.2
Xia, S.3
-
44
-
-
0035501062
-
TGF-beta signaling in cancer - A double-edged sword
-
Akhurst RJ, Derynck R. TGF-beta signaling in cancer-a double-edged sword. Trends Cell Biol 2001;11:S44-51.
-
(2001)
Trends Cell Biol
, vol.11
, pp. S44-51
-
-
Akhurst, R.J.1
Derynck, R.2
-
45
-
-
77952896646
-
TGFbeta signalling: A complex web in cancer progression
-
Ikushima H, Miyazono K. TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer 2010;10:415-24.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 415-424
-
-
Ikushima, H.1
Miyazono, K.2
-
46
-
-
0034214211
-
Mitogenic conversion of transforming growth factor-beta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer
-
Park BJ, Park JI, Byun DS, et al. Mitogenic conversion of transforming growth factor-beta1 effect by oncogenic Ha-Ras-induced activation of the mitogen-activated protein kinase signaling pathway in human prostate cancer. Cancer Res 2000; 60:3031-8.
-
(2000)
Cancer Res
, vol.60
, pp. 3031-3038
-
-
Park, B.J.1
Park, J.I.2
Byun, D.S.3
-
47
-
-
0031764714
-
A proliferative effect of transforming growth factor-beta1 on a human prostate cancer cell line, TSU-Pr1
-
Lamm ML, Sintich SM, Lee C. A proliferative effect of transforming growth factor-beta1 on a human prostate cancer cell line, TSU-Pr1. Endocrinology 1998;139:787-90.
-
(1998)
Endocrinology
, vol.139
, pp. 787-790
-
-
Lamm, M.L.1
Sintich, S.M.2
Lee, C.3
|