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Volumn 26, Issue 12, 2014, Pages 861-869

An acute injection of corticosterone increases thyrotrophin-releasing hormone expression in the paraventricular nucleus of the hypothalamus but interferes with the rapid hypothalamus pituitary thyroid axis response to cold in male rats

Author keywords

Brown adipose tissue; Cold exposure; Corticosterone; Thyroid axis; Thyrotrophin releasing hormone

Indexed keywords

CORTICOSTERONE; IODIDE PEROXIDASE; IODOTHYRONINE DEIODINASE TYPE II; PRO-THYROTROPIN RELEASING HORMONE; PROTEIN PRECURSOR; PROTIRELIN; PYROGLUTAMIC ACID; THYROTROPIN;

EID: 84910675029     PISSN: 09538194     EISSN: 13652826     Source Type: Journal    
DOI: 10.1111/jne.12224     Document Type: Article
Times cited : (17)

References (50)
  • 1
    • 79955977007 scopus 로고    scopus 로고
    • Physiological importance and control of non-shivering facultative thermogenesis
    • Silva JE. Physiological importance and control of non-shivering facultative thermogenesis. Front Biosci (Schol Ed) 2011; 3: 352-371.
    • (2011) Front Biosci (Schol Ed) , vol.3 , pp. 352-371
    • Silva, J.E.1
  • 3
    • 84900404900 scopus 로고    scopus 로고
    • Thyroid hormone regulation of metabolism
    • Mullur R, Liu YY, Brent GA. Thyroid hormone regulation of metabolism. Physiol Rev 2014; 94: 355-382.
    • (2014) Physiol Rev , vol.94 , pp. 355-382
    • Mullur, R.1    Liu, Y.Y.2    Brent, G.A.3
  • 4
    • 0025612087 scopus 로고
    • Cold exposure elevates cellular levels of messenger ribonucleic acid encoding thyrotropin-releasing hormone in paraventricular nucleus despite elevated levels of thyroid hormones
    • Zoeller RT, Kabeer N, Albers HE. Cold exposure elevates cellular levels of messenger ribonucleic acid encoding thyrotropin-releasing hormone in paraventricular nucleus despite elevated levels of thyroid hormones. Endocrinology 1990; 127: 2955-2962.
    • (1990) Endocrinology , vol.127 , pp. 2955-2962
    • Zoeller, R.T.1    Kabeer, N.2    Albers, H.E.3
  • 5
    • 0027213869 scopus 로고
    • Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus
    • Uribe RM, Redondo JL, Charli JL, Joseph-Bravo P. Suckling and cold stress rapidly and transiently increase TRH mRNA in the paraventricular nucleus. Neuroendocrinology 1993; 58: 140-145.
    • (1993) Neuroendocrinology , vol.58 , pp. 140-145
    • Uribe, R.M.1    Redondo, J.L.2    Charli, J.L.3    Joseph-Bravo, P.4
  • 6
    • 0035676914 scopus 로고    scopus 로고
    • Differential responses of thyrotropin releasing hormone (TRH) neurons to cold exposure or suckling indicate functional heterogeneity of the TRH system in the paraventricular nucleus of the rat hypothalamus
    • Sánchez E, Uribe RM, Corkidi G, Zoeller RT, Cisneros M, Zacarias M, Morales-Chapa C, Charli JL, Joseph-Bravo P. Differential responses of thyrotropin releasing hormone (TRH) neurons to cold exposure or suckling indicate functional heterogeneity of the TRH system in the paraventricular nucleus of the rat hypothalamus. Neuroendocrinology 2001; 74: 407-422.
    • (2001) Neuroendocrinology , vol.74 , pp. 407-422
    • Sánchez, E.1    Uribe, R.M.2    Corkidi, G.3    Zoeller, R.T.4    Cisneros, M.5    Zacarias, M.6    Morales-Chapa, C.7    Charli, J.L.8    Joseph-Bravo, P.9
  • 9
    • 10744221610 scopus 로고    scopus 로고
    • Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis
    • Christoffolete MA, Linardi CC, de Jesus L, Ebina KN, Carvalho SD, Ribeiro MO, Rabelo R, Curcio C, Martins L, Kimura ET, Bianco AC. Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis. Diabetes 2004; 53: 577-584.
    • (2004) Diabetes , vol.53 , pp. 577-584
    • Christoffolete, M.A.1    Linardi, C.C.2    de Jesus, L.3    Ebina, K.N.4    Carvalho, S.D.5    Ribeiro, M.O.6    Rabelo, R.7    Curcio, C.8    Martins, L.9    Kimura, E.T.10    Bianco, A.C.11
  • 10
    • 34748839826 scopus 로고    scopus 로고
    • Cold exposure increases the biosynthesis and proteolytic processing of prothyrotropin-releasing hormone in the hypothalamic paraventricular nucleus via beta-adrenoreceptors
    • Perello M, Stuart RC, Vaslet CA, Nillni EA. Cold exposure increases the biosynthesis and proteolytic processing of prothyrotropin-releasing hormone in the hypothalamic paraventricular nucleus via beta-adrenoreceptors. Endocrinology 2007; 148: 4952-4964.
    • (2007) Endocrinology , vol.148 , pp. 4952-4964
    • Perello, M.1    Stuart, R.C.2    Vaslet, C.A.3    Nillni, E.A.4
  • 11
    • 0026803136 scopus 로고
    • Regulation of corticotropin-releasing hormone receptors and hypothalamic pituitary adrenal axis responsiveness during cold stress
    • Hauger RL, Aguilera G. Regulation of corticotropin-releasing hormone receptors and hypothalamic pituitary adrenal axis responsiveness during cold stress. J Neuroendocrinol 1992; 4: 617-624.
    • (1992) J Neuroendocrinol , vol.4 , pp. 617-624
    • Hauger, R.L.1    Aguilera, G.2
  • 12
    • 84896105340 scopus 로고    scopus 로고
    • Glucocorticoid actions on synapses, circuits, and behavior: implications for the energetics of stress
    • Myers B, McKlveen JM, Herman JP. Glucocorticoid actions on synapses, circuits, and behavior: implications for the energetics of stress. Front Neuroendocrinol 2014; 35: 180-196.
    • (2014) Front Neuroendocrinol , vol.35 , pp. 180-196
    • Myers, B.1    McKlveen, J.M.2    Herman, J.P.3
  • 13
    • 79951775871 scopus 로고    scopus 로고
    • Corticosterone pretreatment suppresses stress-induced hypothalamic-pituitary-adrenal axis activity via multiple actions that vary with time, site of action, and de novo protein synthesis
    • Osterlund C, Spencer R. Corticosterone pretreatment suppresses stress-induced hypothalamic-pituitary-adrenal axis activity via multiple actions that vary with time, site of action, and de novo protein synthesis. J Endocrinol 2011; 208: 311-322.
    • (2011) J Endocrinol , vol.208 , pp. 311-322
    • Osterlund, C.1    Spencer, R.2
  • 14
    • 81855194745 scopus 로고    scopus 로고
    • Inhibitory effects of corticosterone in the hypothalamic paraventricular nucleus (PVN) on stress-induced adrenocorticotrophic hormone secretion and gene expression in the PVN and anterior pituitary
    • Weiser MJ, Osterlund C, Spencer RL. Inhibitory effects of corticosterone in the hypothalamic paraventricular nucleus (PVN) on stress-induced adrenocorticotrophic hormone secretion and gene expression in the PVN and anterior pituitary. J Neuroendocrinol 2011; 23: 1231-1240.
    • (2011) J Neuroendocrinol , vol.23 , pp. 1231-1240
    • Weiser, M.J.1    Osterlund, C.2    Spencer, R.L.3
  • 15
    • 84866696672 scopus 로고    scopus 로고
    • Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioural paradigms producing varying intensities of stress and physical activity
    • Gutiérrez-Mariscal M, Sánchez E, García-Vázquez AI, Rebolledo-Solleiro D, Charli JL, Joseph-Bravo P. Acute response of hypophysiotropic thyrotropin releasing hormone neurons and thyrotropin release to behavioural paradigms producing varying intensities of stress and physical activity. Regul Pept 2012; 179: 61-70.
    • (2012) Regul Pept , vol.179 , pp. 61-70
    • Gutiérrez-Mariscal, M.1    Sánchez, E.2    García-Vázquez, A.I.3    Rebolledo-Solleiro, D.4    Charli, J.L.5    Joseph-Bravo, P.6
  • 18
    • 84897395869 scopus 로고    scopus 로고
    • Central regulation of hypothalamic-pituitary-thyroid axis under physiological and pathophysiological conditions
    • Fekete C, Lechan RM. Central regulation of hypothalamic-pituitary-thyroid axis under physiological and pathophysiological conditions. Endocr Rev 2014; 35: 159-194.
    • (2014) Endocr Rev , vol.35 , pp. 159-194
    • Fekete, C.1    Lechan, R.M.2
  • 19
    • 0021137324 scopus 로고
    • Effect of acute and chronic psychogenic stress on corticoadrenal and pituitary-thyroid hormones in male rats
    • Armario A, Castellanos JM, Balasch J. Effect of acute and chronic psychogenic stress on corticoadrenal and pituitary-thyroid hormones in male rats. Horm Res 1984; 20: 241-245.
    • (1984) Horm Res , vol.20 , pp. 241-245
    • Armario, A.1    Castellanos, J.M.2    Balasch, J.3
  • 20
    • 0030299791 scopus 로고    scopus 로고
    • Age and gender influence basal and stress-modulated hypothalamic-pituitary-thyroidal function in Fischer 344/N rats
    • Cizza G, Brady L, Esclapes M, Blackman M, Gold P, Chrousos G. Age and gender influence basal and stress-modulated hypothalamic-pituitary-thyroidal function in Fischer 344/N rats. Neuroendocrinology 1996; 64: 440-448.
    • (1996) Neuroendocrinology , vol.64 , pp. 440-448
    • Cizza, G.1    Brady, L.2    Esclapes, M.3    Blackman, M.4    Gold, P.5    Chrousos, G.6
  • 21
    • 0029062892 scopus 로고
    • Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone
    • Kakucska I, Qi Y, Lechan RM. Changes in adrenal status affect hypothalamic thyrotropin-releasing hormone gene expression in parallel with corticotropin-releasing hormone. Endocrinology 1995; 136: 2795-2802.
    • (1995) Endocrinology , vol.136 , pp. 2795-2802
    • Kakucska, I.1    Qi, Y.2    Lechan, R.M.3
  • 22
    • 0029994418 scopus 로고    scopus 로고
    • Interrelations between sympathoadrenal system and hypothalamo pituitary-adrenocortical/thyroid systems in rats exposed to cold stress
    • Fukuhara K, Kvetnansky R, Cizza G, Pacak K, Ohara H, Goldstein DS, Kopin IJ. Interrelations between sympathoadrenal system and hypothalamo pituitary-adrenocortical/thyroid systems in rats exposed to cold stress. J Neuroendocrinol 1996; 8: 533-541.
    • (1996) J Neuroendocrinol , vol.8 , pp. 533-541
    • Fukuhara, K.1    Kvetnansky, R.2    Cizza, G.3    Pacak, K.4    Ohara, H.5    Goldstein, D.S.6    Kopin, I.J.7
  • 23
    • 78650432886 scopus 로고    scopus 로고
    • The systemic inhibition of nitric oxide production rapidly regulates TRH concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stress rats
    • Uribe R, Cisneros M, Vargas MA, Lezama L, Cote-Vélez A, Joseph-Bravo P, Charli JL. The systemic inhibition of nitric oxide production rapidly regulates TRH concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stress rats. Brain Res 2011; 1367: 188-197.
    • (2011) Brain Res , vol.1367 , pp. 188-197
    • Uribe, R.1    Cisneros, M.2    Vargas, M.A.3    Lezama, L.4    Cote-Vélez, A.5    Joseph-Bravo, P.6    Charli, J.L.7
  • 24
    • 0016769832 scopus 로고
    • Effect of dexamethasone on the secretion of thyrotropin in the rat: dose and time relation
    • Ranta T. Effect of dexamethasone on the secretion of thyrotropin in the rat: dose and time relation. Endocrinology 1975; 96: 1566-1570.
    • (1975) Endocrinology , vol.96 , pp. 1566-1570
    • Ranta, T.1
  • 25
    • 38749151881 scopus 로고    scopus 로고
    • Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in animals submitted to food restriction or dehydration-induced anorexia and cold exposure
    • Jaimes-Hoy L, de Gortari P, Joseph-Bravo P. Differential response of TRHergic neurons of the hypothalamic paraventricular nucleus (PVN) in animals submitted to food restriction or dehydration-induced anorexia and cold exposure. Horm Behav 2008; 53: 366-377.
    • (2008) Horm Behav , vol.53 , pp. 366-377
    • Jaimes-Hoy, L.1    de Gortari, P.2    Joseph-Bravo, P.3
  • 27
    • 14544298906 scopus 로고    scopus 로고
    • Dexamethasone represses cAMP rapid upregulation of TRH gene transcription: identification of a composite glucocorticoid response element and a cAMP response element in TRH promoter
    • Cote-Vélez A, Pérez-Marténez L, Díaz-Gallardo MY, Pérez-Monter C, Carreón-Rodríguez A, Charli JL, Joseph-Bravo P. Dexamethasone represses cAMP rapid upregulation of TRH gene transcription: identification of a composite glucocorticoid response element and a cAMP response element in TRH promoter. J Mol Endocrinol 2005; 34: 177-197.
    • (2005) J Mol Endocrinol , vol.34 , pp. 177-197
    • Cote-Vélez, A.1    Pérez-Marténez, L.2    Díaz-Gallardo, M.Y.3    Pérez-Monter, C.4    Carreón-Rodríguez, A.5    Charli, J.L.6    Joseph-Bravo, P.7
  • 28
    • 77952488508 scopus 로고    scopus 로고
    • A rapid interference between glucocorticoids and cAMP-activated signalling in hypothalamic neurones prevents binding of phosphorylated cAMP response element binding protein and glucocorticoid receptor at the CRE-like and composite GRE sites of thyrotrophin releasing hormone
    • Díaz-Gallardo MY, Cote-Vélez A, Charli JL, Joseph-Bravo P. A rapid interference between glucocorticoids and cAMP-activated signalling in hypothalamic neurones prevents binding of phosphorylated cAMP response element binding protein and glucocorticoid receptor at the CRE-like and composite GRE sites of thyrotrophin releasing hormone. J Neuroendocrinol 2010; 22: 282-293.
    • (2010) J Neuroendocrinol , vol.22 , pp. 282-293
    • Díaz-Gallardo, M.Y.1    Cote-Vélez, A.2    Charli, J.L.3    Joseph-Bravo, P.4
  • 34
    • 0036431534 scopus 로고    scopus 로고
    • Regulation of gene promoters of hypothalamic peptides
    • Burbach JP. Regulation of gene promoters of hypothalamic peptides. Front Neuroendocrinol 2002; 23: 342-369.
    • (2002) Front Neuroendocrinol , vol.23 , pp. 342-369
    • Burbach, J.P.1
  • 35
    • 59849117777 scopus 로고    scopus 로고
    • Timing is critical for effective glucocorticoid receptor mediated repression of the cAMP-induced CRH gene
    • van der Laan S, de Kloet ER, Meijer OC. Timing is critical for effective glucocorticoid receptor mediated repression of the cAMP-induced CRH gene. PLoS ONE 2009; 4: e4327.
    • (2009) PLoS ONE , vol.4 , pp. e4327
    • van der Laan, S.1    de Kloet, E.R.2    Meijer, O.C.3
  • 36
    • 46249120866 scopus 로고    scopus 로고
    • Integration of neuroendocrine signals that regulate the activity of hypophysiotropic peptides
    • In: Kerala: Research Signpost
    • Joseph-Bravo P, Cote-Veléz A, Pérez-Martínez L. Integration of neuroendocrine signals that regulate the activity of hypophysiotropic peptides. In: Molecular Endocrinology. Kerala: Research Signpost, 2006: 1-24. http://trnres.com/ebook.php.
    • (2006) Molecular Endocrinology , pp. 1-24
    • Joseph-Bravo, P.1    Cote-Veléz, A.2    Pérez-Martínez, L.3
  • 37
    • 45549097012 scopus 로고    scopus 로고
    • Measurement of immediate-early gene activation- c-fos and beyond
    • Kovács KJ. Measurement of immediate-early gene activation- c-fos and beyond. J Neuroendocrinol 2008; 20: 665-672.
    • (2008) J Neuroendocrinol , vol.20 , pp. 665-672
    • Kovács, K.J.1
  • 38
    • 67949091258 scopus 로고    scopus 로고
    • Glucocorticoid receptor dynamics and gene regulation
    • Biddie SC, Hager GL. Glucocorticoid receptor dynamics and gene regulation. Stress 2009; 12: 193-205.
    • (2009) Stress , vol.12 , pp. 193-205
    • Biddie, S.C.1    Hager, G.L.2
  • 39
    • 33947328249 scopus 로고    scopus 로고
    • Dynamics of protein kinase A signaling at the membrane, in the cytosol, and in the nucleus of neurons in mouse brain slices
    • Gervasi N, Hepp R, Tricoire L, Zhang J, Lambolez B, Paupardin-Trisch D, Vincent P. Dynamics of protein kinase A signaling at the membrane, in the cytosol, and in the nucleus of neurons in mouse brain slices. J Neurosci 2007; 27: 2744-2750.
    • (2007) J Neurosci , vol.27 , pp. 2744-2750
    • Gervasi, N.1    Hepp, R.2    Tricoire, L.3    Zhang, J.4    Lambolez, B.5    Paupardin-Trisch, D.6    Vincent, P.7
  • 40
    • 0025141278 scopus 로고
    • Evidence for thyrotropin-releasing hormone and glucocorticoid receptor-immunoreactive neurons in various preoptic and hypothalamic nuclei of the male rat
    • Cintra A, Fuxe K, Wikström AC, Visser T, Gustafsson JA. Evidence for thyrotropin-releasing hormone and glucocorticoid receptor-immunoreactive neurons in various preoptic and hypothalamic nuclei of the male rat. Brain Res 1990; 506: 139-144.
    • (1990) Brain Res , vol.506 , pp. 139-144
    • Cintra, A.1    Fuxe, K.2    Wikström, A.C.3    Visser, T.4    Gustafsson, J.A.5
  • 41
    • 67650147389 scopus 로고    scopus 로고
    • Efferent projections of thyrotropin-releasing hormone-synthesizing neurons residing in the anterior parvocellular subdivision of the hypothalamic paraventricular nucleus
    • Wittmann G, Füzesi T, Singru PS, Liposits Z, Lechan RM, Fekete C. Efferent projections of thyrotropin-releasing hormone-synthesizing neurons residing in the anterior parvocellular subdivision of the hypothalamic paraventricular nucleus. J Comp Neurol 2009; 515: 313-330.
    • (2009) J Comp Neurol , vol.515 , pp. 313-330
    • Wittmann, G.1    Füzesi, T.2    Singru, P.S.3    Liposits, Z.4    Lechan, R.M.5    Fekete, C.6
  • 42
    • 0026506091 scopus 로고
    • Ethanol blocks the cold-induced increase in thyrotropin-releasing hormone mRNA in paraventricular nuclei but not the cold-induced increase in thyrotropin
    • Zoeller RT, Rudeen PK. Ethanol blocks the cold-induced increase in thyrotropin-releasing hormone mRNA in paraventricular nuclei but not the cold-induced increase in thyrotropin. Brain Res Mol Brain Res 1992; 13: 321-330.
    • (1992) Brain Res Mol Brain Res , vol.13 , pp. 321-330
    • Zoeller, R.T.1    Rudeen, P.K.2
  • 43
    • 0038755185 scopus 로고    scopus 로고
    • Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism
    • Di S, Malcher-Lopes R, Halmos KC, Tasker JG. Nongenomic glucocorticoid inhibition via endocannabinoid release in the hypothalamus: a fast feedback mechanism. J Neurosci 2003; 23: 4850-4857.
    • (2003) J Neurosci , vol.23 , pp. 4850-4857
    • Di, S.1    Malcher-Lopes, R.2    Halmos, K.C.3    Tasker, J.G.4
  • 44
    • 58149466995 scopus 로고    scopus 로고
    • Type 1 cannabinoid receptor-containing axons innervate hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons
    • Deli L, Wittmann G, Kalló I, Lechan RM, Watanabe M, Liposits Z, Fekete C. Type 1 cannabinoid receptor-containing axons innervate hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons. Endocrinology 2009; 150: 98-103.
    • (2009) Endocrinology , vol.150 , pp. 98-103
    • Deli, L.1    Wittmann, G.2    Kalló, I.3    Lechan, R.M.4    Watanabe, M.5    Liposits, Z.6    Fekete, C.7
  • 45
    • 0141669348 scopus 로고    scopus 로고
    • Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides
    • John CD, Christian HC, Morris JF, Flower RJ, Solito E, Buckingham JC. Kinase-dependent regulation of the secretion of thyrotrophin and luteinizing hormone by glucocorticoids and annexin 1 peptides. J Neuroendocrinol 2003; 15: 946-957.
    • (2003) J Neuroendocrinol , vol.15 , pp. 946-957
    • John, C.D.1    Christian, H.C.2    Morris, J.F.3    Flower, R.J.4    Solito, E.5    Buckingham, J.C.6
  • 46
    • 0015715829 scopus 로고
    • Multiple effects of glucocorticoids on TSH secretion in unanesthetized rats
    • Brown MR, Hedge GA. Multiple effects of glucocorticoids on TSH secretion in unanesthetized rats. Endocrinology 1973; 92: 1305-1311.
    • (1973) Endocrinology , vol.92 , pp. 1305-1311
    • Brown, M.R.1    Hedge, G.A.2
  • 47
    • 0035095006 scopus 로고    scopus 로고
    • Thyrotropin receptors in brown adipose tissue: thyrotropin stimulates type II iodothyronine deiodinase and uncoupling protein-1 in brown adipocytes
    • Murakami M, Kamiya Y, Morimura T, Araki O, Imamura M, Ogiwara T, Mizuma H, Mori M. Thyrotropin receptors in brown adipose tissue: thyrotropin stimulates type II iodothyronine deiodinase and uncoupling protein-1 in brown adipocytes. Endocrinology 2001; 142: 1195-1201.
    • (2001) Endocrinology , vol.142 , pp. 1195-1201
    • Murakami, M.1    Kamiya, Y.2    Morimura, T.3    Araki, O.4    Imamura, M.5    Ogiwara, T.6    Mizuma, H.7    Mori, M.8
  • 48
    • 0027199691 scopus 로고
    • Corticosterone inhibits uncoupling protein gene expression in brown adipose tissue
    • Moriscot A, Rabelo R, Bianco AC. Corticosterone inhibits uncoupling protein gene expression in brown adipose tissue. Am J Physiol 1993; 265: E81-E87.
    • (1993) Am J Physiol , vol.265 , pp. E81-E87
    • Moriscot, A.1    Rabelo, R.2    Bianco, A.C.3
  • 49
    • 0037171457 scopus 로고    scopus 로고
    • Opposing effects of glucocorticoids on beta(3)-adrenergic receptor expression in HIB-1B brown adipocytes
    • Bakopanos E, Silva JE. Opposing effects of glucocorticoids on beta(3)-adrenergic receptor expression in HIB-1B brown adipocytes. Mol Cell Endocrinol 2002; 190: 29-37.
    • (2002) Mol Cell Endocrinol , vol.190 , pp. 29-37
    • Bakopanos, E.1    Silva, J.E.2
  • 50
    • 0023216357 scopus 로고
    • Cold-induced increase in brown fat thyroxine 5′-monodeiodinase is attenuated in Zucker obese rat
    • Wu SY, Stern JS, Fisher DA, Glick Z. Cold-induced increase in brown fat thyroxine 5′-monodeiodinase is attenuated in Zucker obese rat. Am J Physiol 1987; 252: E63-E67.
    • (1987) Am J Physiol , vol.252 , pp. E63-E67
    • Wu, S.Y.1    Stern, J.S.2    Fisher, D.A.3    Glick, Z.4


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