Heterogeneity of pancreatic cancer metastases in a single patient revealed by quantitative proteomics

Molecular and Cellular Proteomics

Volumn 13, Issue 11, 2014, Pages 2803-2811

  Kim, Min Sik ^a   Zhong, Yi ^a   Yachida, Shinichi ^a   Rajeshkumar, N V ^a,b   Abel, Melissa L ^c   Marimuthu, Arivusudar ^d   Mudgal, Keshav ^e   Hruban, Ralph H ^a,b   Poling, Justin S ^a   Tyner, Jeffrey W ^c   Maitra, Anirban ^a,b,f   Iacobuzio Donahue, Christine A ^a,b,g   Pandey, Akhilesh ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d INSTITUTE OF BIOINFORMATICS   (India)

^e IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^g MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE INHIBITOR; PROTEOME; R428; TYROSINE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; AXL RECEPTOR TYROSINE KINASE; FUSED ALICYCLIC AROMATIC COMPOUND; ONCOPROTEIN; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; R428 COMPOUND; TRIAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER PATIENT; CELL ISOLATION; CONTROLLED STUDY; DRUG EFFECT; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; LUNG METASTASIS; MASS SPECTROMETRY; MOUSE; NONHUMAN; PANCREAS METASTASIS; PERITONEUM METASTASIS; PERSONALIZED MEDICINE; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE STUDY; TUMOR XENOGRAFT; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG SCREENING; GENETICS; LIVER NEOPLASMS; LUNG NEOPLASMS; MOLECULARLY TARGETED THERAPY; PANCREATIC NEOPLASMS; PATHOLOGY; PERITONEAL NEOPLASMS; SECONDARY; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; BENZOCYCLOHEPTENES; CELLS, CULTURED; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MASS SPECTROMETRY; MICE; MOLECULAR TARGETED THERAPY; PANCREATIC NEOPLASMS; PERITONEAL NEOPLASMS; PRECISION MEDICINE; PROTEIN KINASE INHIBITORS; PROTEOMICS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TRIAZOLES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84910660856     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M114.038547     Document Type: Article

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