Novel pyridine-2,4,6-tricarbohydrazide derivatives: Design, synthesis, characterization and in vitro biological evaluation as α- And β-glucosidase inhibitors

Bioorganic Chemistry

Volumn 57, Issue , 2014, Pages 148-154

  Riaz, Sadaf ^a   Khan, Islam Ullah ^a   Yar, Muhammad ^b   Ashraf, Muhammad ^c   Rehman, Tanzeel Ur ^a   Shaukat, Ayesha ^c   Jamal, Syed Babar ^d   Duarte, Vera C M ^e   Alves, Maria J ^e  

^a GC UNIVERSITY   (Pakistan)

^b Process and Energy Systems Engineering Center PRESTIGE   (Pakistan)

^c THE ISLAMIA UNIVERSITY OF BAHAWALPUR   (Pakistan)

^d INTERNATIONAL ISLAMIC UNIVERSITY   (Pakistan)

^e UNIVERSITY OF MINHO   (Portugal)

Author keywords

Acarbose; Diabetes; MMFF94X + Solvation; Pyridine 2,4,6 tricarbohydrazide; Glucosidase; Glucosidase

Indexed keywords

ALPHA GLUCOSIDASE INHIBITOR; BETA GLUCOSIDASE INHIBITOR; GLYCOSIDASE INHIBITOR; N' 2,N' 4 DIBENZYLIDENE 6 ((2 BENZYLIDENEHYDRAZINYLOXY)METHYL) PYRIDINE 2,4 DICARBOHYDRAZIDE; N' 2,N' 4, N' 6 TRIS(2 HYDROXYBENZYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; N' 2,N' 4,N' 6 TRIS(3 HYDROXYBENZYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; N' 2,N' 4,N' 6 TRIS(4 (DIMETHYLAMINO)BENZYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; N' 2,N' 4,N' 6 TRIS(4 HYDROXYBENZYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; N' 2,N' 4,N' 6 TRIS(4 METHOXYBENZYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; N'2, N'4, N' 6 TRIS(3 PHENYLALLYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; N'2, N'4, N'6 TRIS(3 AMINOBENZYLIDENE)PYRIDINE 2,4,6 TRICARBOHYDRAZIDE; PYRIDINE 2,4,6 TRICARBOHYDRAZIDE DERIVATIVE; UNCLASSIFIED DRUG; ALPHA GLUCOSIDASE; BETA GLUCOSIDASE; PYRIDINE; PYRIDINE DERIVATIVE;

ALMOND; ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; MOLECULAR DOCKING; MOLECULAR MODEL; SACCHAROMYCES CEREVISIAE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; ENZYMOLOGY; HUMAN; METABOLISM; PRUNUS;

ALPHA-GLUCOSIDASES; BETA-GLUCOSIDASE; GLYCOSIDE HYDROLASE INHIBITORS; HUMANS; PRUNUS; PYRIDINES; SACCHAROMYCES CEREVISIAE;

EID: 84910626746     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2014.10.007     Document Type: Article

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