Synaptic release of CCL5 storage vesicles triggers CXCR4 surface expression promoting CTL Migration in response to CXCL12

Journal of Immunology

Volumn 193, Issue 10, 2014, Pages 4952-4961

  Franciszkiewicz, Katarzyna ^a,b,c,f   Boutet, Marie ^a,b,c   Gauthier, Ludiane ^a,b,c   Vergnon, Isabelle ^a,b,c   Peeters, Kelly ^a,b,c   Duc, Olivier ^a,b,c   Besse, Benjamin ^b   De Saint Basile, Geneviève ^d,e   Chouaib, Salem ^a,b,c   Mami Chouaib, Fathia ^a,b,c  

^a INSERM   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UNIVERSITÉ PARIS SACLAY   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f INSTITUT CURIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BREFELDIN A; CHEMOKINE RECEPTOR CXCR4; GRANZYME B; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NOCODAZOLE; RAB27A PROTEIN; RANTES; STROMAL CELL DERIVED FACTOR 1; CCL5 PROTEIN, HUMAN; CXCL12 PROTEIN, HUMAN; CXCR4 PROTEIN, HUMAN; NERVE PROTEIN; RAB PROTEIN; RAB27A PROTEIN, HUMAN; TUMOR ANTIGEN; UNC13B PROTEIN, HUMAN;

ADAPTIVE IMMUNITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL GRANULE; CELL INTERACTION; CELL MIGRATION; CHEMOTAXIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM VESICLE; CYTOTOXIC T LYMPHOCYTE; DEPOLYMERIZATION; EXOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNE SYNAPSE; LYMPHOCYTE MIGRATION; POLARIZATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SYNAPSE; SYNAPSE VESICLE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR CELL LINE; CHEMISTRY; CYTOTOXICITY; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGICAL SYNAPSE; IMMUNOLOGY; MICROTUBULE; PATHOLOGY; SECRETION (PROCESS); SIGNAL TRANSDUCTION;

ANTIGENS, NEOPLASM; CELL LINE, TUMOR; CHEMOKINE CCL5; CHEMOKINE CXCL12; CHEMOTAXIS; CYTOPLASMIC GRANULES; CYTOTOXICITY, IMMUNOLOGIC; EXOCYTOSIS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOLOGICAL SYNAPSES; MICROTUBULES; NERVE TISSUE PROTEINS; RAB GTP-BINDING PROTEINS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84910148539     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401184     Document Type: Article

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