Screening carbohydrate libraries for protein interactions using the direct ESI-MS assay. Applications to libraries of unknown concentration

Journal of the American Society for Mass Spectrometry

Volumn 25, Issue 11, 2014, Pages 1908-1916

  Kitova, Elena N ^a   El Hawiet, Amr ^a,b   Klassen, John S ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Carbohydrate; Library screening; Protein interactions

Indexed keywords

CARBOHYDRATES; ELECTROSPRAY IONIZATION; LIBRARIES; LIGANDS; MASS SPECTROMETRY; MIXTURES; OLIGOSACCHARIDES; SACCHARIFICATION;

CONTROL EXPERIMENTS; ELECTROSPRAY IONIZATION MASS SPECTROMETRY; HUMAN MILK OLIGOSACCHARIDES; LIBRARY SCREENING; PROTEIN CONCENTRATIONS; PROTEIN INTERACTION; RELATIVE ABUNDANCE; SINGLE-CHAIN ANTIBODIES;

PROTEINS;

CARBOHYDRATE; CARBOHYDRATE BINDING PROTEIN; GALECTIN 3; HUMAN MILK OLIGOSACCHARIDE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG; PEPTIDE LIBRARY; PROTEIN;

ARTICLE; BINDING AFFINITY; BINDING SITE; BREAST MILK; CARBOHYDRATE ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG MIXTURE; ELECTROSPRAY MASS SPECTROMETRY; ISOMER; LIGAND BINDING; MOLECULAR LIBRARY; MOLECULAR WEIGHT; PH; PROTEIN INTERACTION; CHEMISTRY; HUMAN; METABOLISM; PEPTIDE LIBRARY; PROCEDURES;

GALECTIN 3; HUMANS; MILK, HUMAN; OLIGOSACCHARIDES; PEPTIDE LIBRARY; PROTEINS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84910134300     PISSN: 10440305     EISSN: 18791123     Source Type: Journal    
DOI: 10.1007/s13361-014-0964-2     Document Type: Article

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