Epigenome analysis reveals TBX5 as a novel transcription factor involved in the activation of rheumatoid arthritis synovial fibroblasts

Journal of Immunology

Volumn 193, Issue 10, 2014, Pages 4945-4951

  Karouzakis, Emmanuel ^a   Trenkmann, Michelle ^a   Gay, Renate E ^a   Michel, Beat A ^a   Gay, Steffen ^a   Neidhart, Michel ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; STROMAL CELL DERIVED FACTOR 1; TRANSCRIPTION FACTOR TBX5; CCL20 PROTEIN, HUMAN; CHROMATIN; CXCL12 PROTEIN, HUMAN; T BOX TRANSCRIPTION FACTOR; T-BOX TRANSCRIPTION FACTOR 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FIBROBLAST; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HISTONE ACETYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PROMOTER REGION; PROTEIN LOCALIZATION; PYROSEQUENCING; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVIUM; TBX5 GENE; UPREGULATION; WESTERN BLOTTING; ACETYLATION; BIOLOGY; CHROMATIN; GENETIC EPIGENESIS; GENETICS; IMMUNOLOGY; METABOLISM; METHYLATION; PATHOLOGY; SIGNAL TRANSDUCTION;

ACETYLATION; ARTHRITIS, RHEUMATOID; CHEMOKINE CCL20; CHEMOKINE CXCL12; CHROMATIN; COMPUTATIONAL BIOLOGY; EPIGENESIS, GENETIC; FIBROBLASTS; HUMANS; INTERLEUKIN-8; METHYLATION; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; T-BOX DOMAIN PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84910108317     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1400066     Document Type: Article

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