Combining physical training with transcranial direct current stimulation to improve gait in Parkinson's disease: A pilot randomized controlled study

Clinical Rehabilitation

Volumn 28, Issue 11, 2014, Pages 1115-1124

  Kaski, D ^a,b   Dominguez, R O ^b   Allum, J H ^c   Islam, A F ^d   Bronstein, A M ^a  

^a CHARING CROSS HOSPITAL   (United Kingdom)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c University ORL Clinic   (Switzerland)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Cerebral cortex; electrical stimulation therapy; exercise therapy; gait; Parkinson's disease

Indexed keywords

AGED; BODY EQUILIBRIUM; COMPLICATION; CONTROLLED STUDY; CONVALESCENCE; DOUBLE BLIND PROCEDURE; FEMALE; FOLLOW UP; GAIT; GAIT DISORDERS, NEUROLOGIC; HUMAN; KINESIOTHERAPY; MALE; MIDDLE AGED; MULTIMODALITY CANCER THERAPY; PARKINSON DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY; PILOT STUDY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; SEVERITY OF ILLNESS INDEX; TRANSCRANIAL DIRECT CURRENT STIMULATION; TREATMENT OUTCOME;

AGED; COMBINED MODALITY THERAPY; DOUBLE-BLIND METHOD; EXERCISE THERAPY; FEMALE; FOLLOW-UP STUDIES; GAIT; GAIT DISORDERS, NEUROLOGIC; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; PILOT PROJECTS; POSTURAL BALANCE; RECOVERY OF FUNCTION; SEVERITY OF ILLNESS INDEX; TRANSCRANIAL DIRECT CURRENT STIMULATION; TREATMENT OUTCOME;

EID: 84910099083     PISSN: 02692155     EISSN: 14770873     Source Type: Journal    
DOI: 10.1177/0269215514534277     Document Type: Article

References (24)

1. Hely MA, Morris JG, Reid WG, Trafficante R. Sydney Multicenter Study of Parkinson's disease: non-L-dopa-responsive problems dominate at 15 years. Mov Disord. 2005 ; 20 (2). 190-199
2. Playford ED, Jenkins IH, Passingham RE, Nutt J, Frackowiak RS, Brooks DJ. Impaired mesial frontal and putamen activation in Parkinson's disease: a positron emission tomography study. Ann Neurol. 1992 ; 32 (2). 151-161
3. Pascual-Leone A, Valls-Sole J, Brasil-Neto JP, Cammarota A, Grafman J, Hallett M. Akinesia in Parkinson's disease. II. Effects of subthreshold repetitive transcranial motor cortex stimulation. Neurol. 1994 ; 44 (5). 892-898
4. Fisher BE, Wu AD, Salem GJ, et al. The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease. Arch Phys Med Rehabil. 2008 ; 89 (7). 1221-1229
5. Williams JA, Imamura M, Fregni F. Updates on the use of non-invasive brain stimulation in physical and rehabilitation medicine. J Rehabil Med. 2009 ; 41 (5). 305-311
6. Kaski D, Dominguez RO, Allum JH, Bronstein AM. Improving gait and balance in patients with leukoaraiosis using transcranial direct current stimulation and physical training: An exploratory study. Neurorehabil Neural Repair. 2013 ;:
7. Alon G, Yungher DA, Shulman LM, Rogers MW. Safety and immediate effect of noninvasive transcranial pulsed current stimulation on gait and balance in Parkinson disease. Neurorehabil Neural Repair. 2012 ; 26 (9). 1089-1095
8. Hunt AL, Sethi KD. The pull test: a history. Mov Disord. 2006 ; 21 (7). 894-899
9. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992 ; 55 (3). 181-184
10. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 ; 12 (3). 189-198
11. Suchowersky O, Gronseth G, Perlmutter J, Reich S, Zesiewicz T, Weiner WJ. Practice parameter: neuroprotective strategies and alternative therapies for Parkinson disease (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurol. 2006 ; 66 (7). 976-982
12. Kaski D, Quadir S, Patel M, Yousif N, Bronstein AM. Enhanced locomotor adaptation after-effect in the 'broken escalator' phenomenon using anodal tDCS. J Neurophysiol. 2012 ; 107 (9). 2493-2505
13. Toro BN, Nester C, Farren P. A review of observational gait assessment in clinical practice. Physiotherapy Theory Practice. 2003 ; 19: 137-149
14. Lang A Therapy of Parkinson's disease. Koller WC Paulson G, ed. New York: Marcel Dekker ; 1995: 21-46.
15. Allum JH, Carpenter MG. A speedy solution for balance and gait analysis: angular velocity measured at the centre of body mass. Curr Opin Neurol. 2005 ; 18 (1). 15-21
16. Fahn S, Oakes D, Shoulson I, et al. Levodopa and the progression of Parkinson's disease. New Engl J Med. 2004 ; 351 (24). 2498-2508
17. Almeida QJ, Frank JS, Roy EA, Patla AE, Jog MS. Dopaminergic modulation of timing control and variability in the gait of Parkinson's disease. Mov Disord. 2007 ; 22 (12). 1735-1742
18. Stefani A, Peppe A, Pierantozzi M, et al. Multi-target strategy for Parkinsonian patients: the role of deep brain stimulation in the centromedian-parafascicularis complex. Brain Res Bull. 2009 ; 78 (2-3). 113-118
19. Khedr EM, Rothwell JC, Shawky OA, Ahmed MA, Hamdy A. Effect of daily repetitive transcranial magnetic stimulation on motor performance in Parkinson's disease. Mov Disord. 2006 ; 21 (12). 2201-2205
20. Lomarev MP, Kanchana S, Bara-Jimenez W, Iyer M, Wassermann EM, Hallett M. Placebo-controlled study of rTMS for the treatment of Parkinson's disease. Mov Disord. 2006 ; 21 (3). 325-331
21. Benninger DH, Berman BD, Houdayer E, et al. Intermittent theta-burst transcranial magnetic stimulation for treatment of Parkinson disease. Neurology. 2011 ; 76 (7). 601-609
22. Benninger DH, Lomarev M, Lopez G, et al. Transcranial direct current stimulation for the treatment of Parkinson's disease. J Neurol Neurosurg Psychiatry. 2010 ; 81 (10). 1105-1111
23. Geroin C, Picelli A, Munari D, Waldner A, Tomelleri C, Smania N. Combined transcranial direct current stimulation and robot-assisted gait training in patients with chronic stroke: a preliminary comparison. Clin Rehabil. 2011 ; 25 (6). 537-548
24. Jeffery DT, Norton JA, Roy FD, Gorassini MA. Effects of transcranial direct current stimulation on the excitability of the leg motor cortex. Experimentelle Hirnforschung Experimentation Cerebrale. 2007 ; 182 (2). 281-287