Toll-like receptor 4 implicated in acute lung injury induced by paraquat poisoning in mice

International Journal of Clinical and Experimental Medicine

Volumn 7, Issue 10, 2014, Pages 3392-3397

  Liu, Wei ^a   Shan, Li Ping ^a   Dong, Xue Song ^a   Liu, Zhi ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Acute lung injury; Inflammation; Paraquat; Poisoning; Toll like receptor 4

Indexed keywords

INTERLEUKIN 1BETA; MESSENGER RNA; PARAQUAT; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL GAS; ARTICLE; CARBON DIOXIDE TENSION; CELL INFILTRATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; INFLAMMATION; INFLAMMATORY CELL; LUNG ALVEOLUS WALL; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; OXYGEN TENSION; PARAQUAT POISONING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; WESTERN BLOTTING;

EID: 84910070316     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Serra A, Domingos F, Prat MM. Paraquat intoxication. Acta Med Port 2003; 16: 25-32.
2. Bertolote JM, Fleischmann A. Deaths from pesticide poisoning: a global respons. Br J Psych 2006; 189: 201-203.
3. Dinis-Oliveira RJ, De Jesús Valle MJ, Bastos ML. Kinetics of paraquat in the isolated rat lung: influence of sodium depletion. Xenobiotica 2006; 36: 724-737.
4. Chen CM, Lua AC. Lung toxicity of paraquat in the rat. J Toxicol Environ Health A 2000; 60: 477-487.
5. Dinis-Oliveira RJ, Duarte JA, Sánchez-Navarro A, Remião F, Bastos ML, Carvalho F. Paraquat poisonings: mechanisms of lung toxicity, clinical features and treatment. Crit Rev Toxicol 2008; 38: 13-71.
6. Zhou B, Zhou H, Ling S, Guo D, Yan Y, Zhou F, Wu Y. Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2. Oncol Rep 2011; 25: 503-511.
7. Hoth JJ, Wells JD, Brownlee NA, Hiltbold EM, Meredith JW, McCall CE, Yoza BK. Toll-like receptor 4 dependent responses to lung injury in a murine model of pulmonary contusion. Shock 2009; 31: 376-381.
8. Villar J, Cabrera N, Casula M. Mechanical ventilation modulates Toll-like receptor signaling pathway in a sepsis-induced lung injury model. Intensive Care Med 2010; 36: 1049-1057.
9. Mydlík M, Derzsiová K, Frank K. Renal replacement therapy in acute poisonings-one center experience. Przegl Lek 2013; 70: 381-385.
10. Chang JB, Lin CC, Chiou JF, Mau SY, Liu TZ, Chen CH. Treatment of acute paraquat intoxication using recommended megadose of vitamin C: a reappraisal. Free Radic Res 2013; 47: 991-1001.
11. Yang H, Wen Y, Hou-you Y, Yu-tong W, Chuan-ming L, Jian X, Lu H. Combined treatment with bone marrow mesenchymal stem cells and methylprednisolone in paraquat-induced acute lung injury. BMC Emerg Med 2013; 13 Suppl 1: S5.
12. Whitehead GS, Grasman KA, Kimmel EC. Lung function and airway inflammation in rats following exposure to combustion products of carbon-graphite/epoxy composite material: comparison to a rodent model of acute lung injury. Toxicology 2013; 83: 175-197.
13. Akira S. Mammalian Toll-like receptors. Curr Opin Immunol 2003; 15: 5-11.
14. Medzhitov R, Janeway C Jr. Innate immunity. N Engl J Med 2000; 343: 338-344.
15. Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in TLR4 gene. Science 1998; 282: 2085-2088.
16. Qureshi ST, Lariviere L, Leveque G, Clermont S, Moore KJ, Gros P, Malo D. Endotoxin-tolerant mice have mutations in Toll-like receptor 4(Tlr4). J Exp Med 1999; 189: 615-625.
17. Laflamme N, Rivest S. Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components. FASEB J 2001; 15: 155-163.
18. Ohashi K, Burkart V, Flohe S, Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex. J Immunol 2000; 164: 558-561.
19. Bulut Y, Faure E, Thomas L, Karahashi H, Michelsen KS, Equils O, Morrison SG, Morrison RP, Arditi M. Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway. J Immunol 2002; 168: 1435-1440.
20. Jian XD, Li M, Zhang YJ. Role of growth factors in acute lung injury induced by paraquat in a rat model. Hum Exp Toxicol 2011; 30: 460-469.
21. Wu HS, Zhang JX, Wang L, Tian Y, Wang H. Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in mice. Hepatobiliary Pancreat Dis Int 2004; 3: 250-253.
22. Tsung A, Hoffman RA, Izuishi K, Critchlow ND, Nakao A. Hepatic ischemia/reperfusion injury involves functional TLR4 signaling in nonparenchymal cells. J Immunol 2005; 175: 7661-7668.
23. Oyama JI, Blais C, Liu X, Pu M, Kobzik L. Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient mice. Circulation 2004; 109: 784-789.