Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers

Oncotarget

Volumn 5, Issue 19, 2014, Pages 9349-9361

  Guo, Wei ^a   Lu, Jianjun ^c   Dai, Meng ^a   Wu, Taihua ^a   Yu, Zhenlong ^a   Wang, Jingshu ^b   Chen, Wangbing ^b   Shi, Dingbo ^b   Yu, Wendan ^a   Xiao, Yao ^a   Yi, Canhui ^a   Tang, Zhipeng ^a   Xu, Tingting ^a   Xiao, Xiangsheng ^b   Yuan, Yuhui ^a   Liu, Quentin ^a,b   Du, Guangwei ^d   Deng, Wuguo ^a,b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

CBP; HTERT; Lung cancer; Promoter; Sp1

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; LUCIFERASE; PREGNANCY SPECIFIC BETA1 GLYCOPROTEIN; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE; PROTEIN BINDING; SP1 PROTEIN, HUMAN; TELOMERASE; TERT PROTEIN, HUMAN; TRANSCRIPTION FACTOR SP1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CELL SPECIFICITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMORTALIZED CELL LINE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG CANCER CELL LINE; LUNG CARCINOGENESIS; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; OVERALL SURVIVAL; PROMOTER REGION; PROTEIN ACETYLATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SURVIVAL TIME; TISSUE MICROARRAY; TUMOR XENOGRAFT; UPREGULATION; ACETYLATION; ADENOCARCINOMA; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CANCER TRANSPLANTATION; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LUNG TUMOR; METABOLISM; MORTALITY; NUDE MOUSE; PATHOLOGY; PROGNOSIS; RNA INTERFERENCE; TRANSCRIPTION INITIATION; TUMOR CELL LINE; XENOGRAFT;

ACETYLATION; ADENOCARCINOMA; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CREB-BINDING PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROGNOSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA INTERFERENCE; RNA, SMALL INTERFERING; SP1 TRANSCRIPTION FACTOR; TELOMERASE; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84910050332     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2430     Document Type: Article

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