Fibulin-3 negatively regulates ALDH1 via c-MET suppression and increases γ-radiation-induced sensitivity in some pancreatic cancer cell lines

Biochemical and Biophysical Research Communications

Volumn 454, Issue 3, 2014, Pages 369-375

  Kim, In Gyu ^a,b   Lee, Jae Ha ^a,b   Kim, Seo Yoen ^a   Kim, Jeong Yul ^a   Cho, Eun Wie ^c  

^a Korea Atomic Energy Research Institute   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

Author keywords

ALDH; c MET; Cancer stem cell; Fibulin 3

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 1; CYTOTOXIC AGENT; FIBULIN; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; EFEMP1 PROTEIN, HUMAN; ISOENZYME; MET PROTEIN, HUMAN; RETINAL DEHYDROGENASE; SCLEROPROTEIN;

ARTICLE; CANCER PROGNOSIS; CANCER STEM CELL; CELL GROWTH; CPG ISLAND; EPITHELIAL MESENCHYMAL TRANSITION; GAMMA RADIATION; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; METHYLATION; PANCREATIC CANCER CELL LINE; PROMOTER REGION; AMINO ACID SEQUENCE; CHEMISTRY; DNA METHYLATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PANCREAS; PANCREATIC NEOPLASMS; PATHOLOGY; RADIATION RESPONSE; TUMOR CELL LINE;

AMINO ACID SEQUENCE; BASE SEQUENCE; CELL LINE, TUMOR; CPG ISLANDS; DNA METHYLATION; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX PROTEINS; GAMMA RAYS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; ISOENZYMES; NEOPLASTIC STEM CELLS; PANCREAS; PANCREATIC NEOPLASMS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-MET; RETINAL DEHYDROGENASE;

EID: 84910017824     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.10.084     Document Type: Article

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