MiRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts

Cell and Bioscience

Volumn 4, Issue 1, 2014, Pages

  Read, Danielle E ^a   Gupta, Ananya ^a   Ladilov, Yury ^b   Samali, Afshin ^a   Gupta, Sanjeev ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Apoptosis; ER stress; MicroRNAs; Mir 7a; Myocardial infarction; Unfolded protein response

Indexed keywords

RATTUS;

EID: 84910015462     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-4-56     Document Type: Article

References (40)

1. Dumont EA, Hofstra L, van Heerde WL, van den Eijnde S, Doevendans PA, DeMuinck E, Daemen MA, Smits JF, Frederik P, Wellens HJ, Daemen MJ, Reutelingsperger CP. Cardiomyocyte death induced by myocardial ischemia and reperfusion: measurement with recombinant human annexin-V in a mouse model. Circulation 2000, 102(13):1564-1568. 10.1161/01.CIR.102.13.1564, 11004148.
2. Glembotski CC. The role of the unfolded protein response in the heart. J Mol Cell Cardiol 2008, 44(3):453-459. 10.1016/j.yjmcc.2007.10.017, 2746718, 18054039.
3. Azfer A, Niu J, Rogers LM, Adamski FM, Kolattukudy PE. Activation of endoplasmic reticulum stress response during the development of ischemic heart disease. Am J Physiol Heart Circ Physiol 2006, 291(3):H1411-H1420. 10.1152/ajpheart.01378.2005, 1575464, 16617122.
4. Szegezdi E, Duffy A, O'Mahoney ME, Logue SE, Mylotte LA, O'Brien T, Samali A. ER stress contributes to ischemia-induced cardiomyocyte apoptosis. Biochem Biophys Res Commun 2006, 349(4):1406-1411. 10.1016/j.bbrc.2006.09.009, 16979584.
5. Ron D, Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 2007, 8(7):519-529. 10.1038/nrm2199, 17565364.
6. Harding HP, Zhang Y, Ron D. Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 1999, 397(6716):271-274. 10.1038/16729, 9930704.
7. Lu PD, Harding HP, Ron D. Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response. J Cell Biol 2004, 167(1):27-33. 10.1083/jcb.200408003, 2172506, 15479734.
8. Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding HP, Clark SG, Ron D. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 2002, 415(6867):92-96. 10.1038/415092a, 11780124.
9. Haze K, Yoshida H, Yanagi H, Yura T, Mori K. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 1999, 10(11):3787-3799. 10.1091/mbc.10.11.3787, 25679, 10564271.
10. Puthalakath H, O'Reilly LA, Gunn P, Lee L, Kelly PN, Huntington ND, Hughes PD, Michalak EM, McKimm-Breschkin J, Motoyama N, Gotoh T, Akira S, Bouillet P, Strasser A. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 2007, 129(7):1337-1349. 10.1016/j.cell.2007.04.027, 17604722.
11. Szegezdi E, Logue SE, Gorman AM, Samali A. Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 2006, 7(9):880-885. 10.1038/sj.embor.7400779, 1559676, 16953201.
12. Cawley K, Logue SE, Gorman AM, Zeng Q, Patterson J, Gupta S, Samali A. Disruption of microRNA biogenesis confers resistance to ER stress-induced cell death upstream of the mitochondrion. PLoS One 2013, 8(8):e73870. 10.1371/journal.pone.0073870, 3747093, 23977393.
13. Ambros V. The functions of animal microRNAs. Nature 2004, 431(7006):350-355. 10.1038/nature02871, 15372042.
14. Bushati N, Cohen SM. microRNA functions. Annu Rev Cell Dev Biol 2007, 23:175-205. 10.1146/annurev.cellbio.23.090506.123406, 17506695.
15. Hwang HW, Mendell JT. MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 2006, 94(6):776-780. 10.1038/sj.bjc.6603023, 2361377, 16495913.
16. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297. 10.1016/S0092-8674(04)00045-5, 14744438.
17. Pillai RS, Bhattacharyya SN, Filipowicz W. Repression of protein synthesis by miRNAs: how many mechanisms?. Trends Cell Biol 2007, 17(3):118-126. 10.1016/j.tcb.2006.12.007, 17197185.
18. Babar IA, Slack FJ, Weidhaas JB. miRNA modulation of the cellular stress response. Future Oncol 2008, 4(2):289-298. 10.2217/14796694.4.2.289, 18407740.
19. Leung AK, Calabrese JM, Sharp PA. Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci U S A 2006, 103(48):18125-18130. 10.1073/pnas.0608845103, 1838717, 17116888.
20. Liu N, Bezprozvannaya S, Williams AH, Qi X, Richardson JA, Bassel-Duby R, Olson EN. microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev 2008, 22(23):3242-3254. 10.1101/gad.1738708, 2600761, 19015276.
21. van Rooij E, Olson EN. MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nat Rev Drug Discov 2012, 11(11):860-872. 10.1038/nrd3864, 23080337.
22. Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF, Srivastava D. miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med 2011, 208(3):549-560. 10.1084/jem.20101547, 3058576, 21383058.
23. Lytton J, Westlin M, Hanley MR. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 1991, 266(26):17067-17071.
24. Heifetz A, Keenan RW, Elbein AD. Mechanism of action of tunicamycin on the UDP-GlcNAc:dolichyl-phosphate Glc-NAc-1-phosphate transferase. Biochemistry 1979, 18(11):2186-2192. 10.1021/bi00578a008, 444447.
25. Yauk CL, Rowan-Carroll A, Stead JD, Williams A. Cross-platform analysis of global microRNA expression technologies. BMC Genomics 2010, 11:330. 10.1186/1471-2164-11-330, 2890562, 20504329.
26. Gupta S, Read DE, Deepti A, Cawley K, Gupta A, Oommen D, Verfaillie T, Matus S, Smith MA, Mott JL, Agostinis P, Hetz C, Samali A. Perk-dependent repression of miR-106b-25 cluster is required for ER stress-induced apoptosis. Cell Death Dis 2012, 3:e333. 10.1038/cddis.2012.74, 3388242, 22739985.
27. Rao PK, Toyama Y, Chiang HR, Gupta S, Bauer M, Medvid R, Reinhardt F, Liao R, Krieger M, Jaenisch R, Lodish HF, Blelloch R. Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res 2009, 105(6):585-594. 10.1161/CIRCRESAHA.109.200451, 2828903, 19679836.
28. Cawley K, Deegan S, Samali A, Gupta S. Assays for detecting the unfolded protein response. Methods Enzymol 2011, 490:31-51.
29. Samali A, Fitzgerald U, Deegan S, Gupta S. Methods for monitoring endoplasmic reticulum stress and the unfolded protein response. Int J Cell Biol 2010, 2010:830307. 2821749, 20169136.
30. Liu N, Olson EN. MicroRNA regulatory networks in cardiovascular development. Dev Cell 2010, 18(4):510-525. 10.1016/j.devcel.2010.03.010, 2922691, 20412767.
31. Fasanaro P, Greco S, Ivan M, Capogrossi MC, Martelli F. microRNA: emerging therapeutic targets in acute ischemic diseases. Pharmacol Ther 2010, 125(1):92-104. 10.1016/j.pharmthera.2009.10.003, 19896977.
32. Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell 2008, 2(3):219-229. 10.1016/j.stem.2008.01.016, 2293325, 18371447.
33. Xu C, Lu Y, Pan Z, Chu W, Luo X, Lin H, Xiao J, Shan H, Wang Z, Yang B. The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes. J Cell Sci 2007, 120(Pt 17):3045-3052.
34. Kalinowski FC, Brown RA, Ganda C, Giles KM, Epis MR, Horsham J, Leedman PJ. microRNA-7: A tumor suppressor miRNA with therapeutic potential. Int J Biochem Cell Biol 2014, 54:312-317. doi:10.1016/j.biocel.2014.05.040. Epub 2014 Jun 5..
35. de Chevigny A, Core N, Follert P, Gaudin M, Barbry P, Beclin C, Cremer H. miR-7a regulation of Pax6 controls spatial origin of forebrain dopaminergic neurons. Nat Neurosci 2012, 15(8):1120-1126. 10.1038/nn.3142, 22729175.
36. Latreille M, Hausser J, Stutzer I, Zhang Q, Hastoy B, Gargani S, Kerr-Conte J, Pattou F, Zavolan M, Esguerra JL, Eliasson L, Rulicke T, Rorsman P, Stoffel M. MicroRNA-7a regulates pancreatic beta cell function. J Clin Invest 2014, 124(6):2722-2735. 10.1172/JCI73066, 4038573, 24789908.
37. Sissons JR, Peschon JJ, Schmitz F, Suen R, Gilchrist M, Aderem A. Cutting edge: microRNA regulation of macrophage fusion into multinucleated giant cells. J Immunol 2012, 189(1):23-27. 10.4049/jimmunol.1102477, 3381877, 22661094.
38. Li B, Li R, Zhang C, Bian HJ, Wang F, Xiao J, Liu SW, Yi W, Zhang MX, Wang SX, Zhang Y, Su GH, Ji XP. MicroRNA-7a/b protects against cardiac myocyte injury in ischemia/reperfusion by targeting poly(ADP-ribose) polymerase. PLoS One 2014, 9(3):e90096. 10.1371/journal.pone.0090096, 3940823, 24594984.
39. Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2008, 7(12):1013-1030. 10.1038/nrd2755, 19043451.
40. Ladilov YV, Balser C, Piper HM. Protection of rat cardiomyocytes against simulated ischemia and reoxygenation by treatment with protein kinase C activator. Circ Res 1998, 82(4):451-457. 10.1161/01.RES.82.4.451, 9506705.