The p38 MAPK-regulated PKD1/CREB/Bcl-2 pathway contributes to selenite-induced colorectal cancer cell apoptosis in vitro and in vivo

Cancer Letters

Volumn 354, Issue 1, 2014, Pages 189-199

  Hui, Kaiyan ^a   Yang, Yang ^a   Shi, Kejian ^a   Luo, Hui ^a   Duan, Jing ^a   An, Jiajia ^a   Wu, Pa ^a   Ci, Yali ^a   Shi, Lei ^a   Xu, Caimin ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Apoptosis; CREB; P38 MAPK; PKD1; Selenite

Indexed keywords

CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; POLYCYSTIN 1; PROTEIN BCL 2; SELENITE; CREB1 PROTEIN, HUMAN; POLYCYSTIC KIDNEY DISEASE 1 PROTEIN; POLYCYSTIN; SELENIOUS ACID;

APOPTOSIS; ARTICLE; CANCER CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL CANCER; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PROTEIN PHOSPHORYLATION; TUMOR GROWTH; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CHEMISTRY; COLORECTAL TUMOR; CREB; GENE EXPRESSION REGULATION; METABOLISM; MOUSE; P38 MAPK; PHOSPHORYLATION; PKD1; TUMOR CELL LINE;

APOPTOSIS; CREB; P38 MAPK; PKD1; SELENITE;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; SELENIOUS ACID; TRPP CATION CHANNELS;

EID: 84910006087     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.08.009     Document Type: Article

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