Syk inhibits the activity of protein kinase a by phosphorylating tyrosine 330 of the catalytic subunit

Journal of Biological Chemistry

Volumn 288, Issue 15, 2013, Pages 10870-10881

  Yu, Shuai ^a   Huang, He ^a   Iliuk, Anton ^b   Wang, Wen Horng ^a   Jayasundera, Keerthi B ^b   Tao, W Andy ^a,b,c   Post, Carol B ^a,c   Geahlen, Robert L ^a,c  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

^c Purdue University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; CATALYTIC SUBUNITS; PROTEIN KINASE A; SIGNALING PATHWAYS; TYROSINE KINASE;

ENZYMES; PHOSPHORYLATION; PROTEINS; TUMORS;

AMINO ACIDS;

CARBOXY TERMINAL TELOPEPTIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; PROTEIN INHIBITOR; PROTEIN KINASE SYK; TYROSINE;

ARTICLE; BCL2 GENE; BREAST CANCER; CANCER CELL; CATALYSIS; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE; HUMAN; HUMAN CELL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; PROTEOMICS; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS;

AMINO ACID MOTIFS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CREB-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA DAMAGE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TYROSINE;

EID: 84876242542     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.426130     Document Type: Article

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