A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma

Cell Death and Disease

Volumn 4, Issue 6, 2013, Pages

  Maillet, A ^a   Yadav, S ^a   Loo, Y L ^a   Sachaphibulkij, K ^a   Pervaiz, S ^a,b,c,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c DUKE NUS MEDICAL SCHOOL   (Singapore)

^d SINGAPORE MIT ALLIANCE   (Singapore)

Author keywords

cancer therapy; mitochondria; novel compound; ROS

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE INHIBITOR; CISPLATIN; DOXORUBICIN; OSMIUM DERIVATIVE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; Z VAD FMK;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL LEVEL; CELL STRUCTURE; CELL VIABILITY; CHEMOSENSITIVITY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; ELECTRON TRANSPORT; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

MURINAE;

EID: 84879615064     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.185     Document Type: Article

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